TCR signaling (Homo sapiens)
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18, 31, 36
9
46
23, 34, 42
11, 16, 63
1, 29
44
2, 35
12, 13, 56, 74
20
14, 66
7, 67
17, 69
72
9
9
5, 8, 40
9
49
3, 37, 57, 68, 73
13, 56
72
22
29, 45
9, 39
78
42
7
9
10, 15, 24, 59, 70
22, 33, 64
4, 53
58
43, 51
16, 63
67
79
29
9
77, 79
19, 28
76
1, 29, 58
78
41, 50, 52, 71
13, 56
25-27, 32, 55
16, 63
42
6
1
30
28
nucleoplasm
cytosol
Ub-580-UBC(533-608)
HLA class II histocompatibility antigen, DP alpha chain precursor
HLA class II histocompatibility antigen, DRB1-1 beta chain
Antigen
HLA class II histocompatibility antigen, DRB1-12 beta chain
HLA class II histocompatibility antigen, DRB1-8 beta chain
p-MAP3K7
p-Y771,Y783,Y1254-PLCG1
ITK
UBE2V1
HLA class II histocompatibility antigen, DRB1-13 beta chain
Pi
HLA class II histocompatibility antigen, DRB1-7 beta chain
p-Y113,128,145-LCP2
HLA class II histocompatibility antigen, DRB1-16 beta chain
HLA class II histocompatibility antigen, DP
PSMB8
ATP
BCL10
PSMC1
WAS
RIPK2
HLA class II histocompatibility antigen, DQ beta 2 chain
PDPK1
HLA class II histocompatibility antigen, DRB1-16 beta chain
SLP-76 bound to
Gads:LAT
PAK3
Ub-124-UBC(77-152)
PAK3
PIK3R2
p-T184,T187-MAP3K7
HLA class II histocompatibility antigen, DR beta 4 chain
HLA class II histocompatibility antigen, DRB1-11 beta chain
HLA class II histocompatibility antigen, DQ
TRAC
TRAV19
p-6Y-CD247
CD4
HLA class II histocompatibility antigen, DRB1-11 beta chain
p-S552-CARD11
CD3D
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor
HLA class II histocompatibility antigen, DR beta 5 chain
TRAC
HLA class II histocompatibility antigen, DR-1 beta chain precursor
ADP
TRBV12-3
TCRA
CD45,CD148
TRBC1
GRAP2
p-5Y-LAT
GRAP2
ADP
K63polyUb-NEMO
CHUK
HLA class II histocompatibility antigen, DRB1-12 beta chain
ATP
Ub-48-RPS27A(1-76)
T-cell receptor alpha chain V region PY14 precursor
PSMD12
UBE2N
HLA class II histocompatibility antigen, DRB1-8 beta chain
HLA class II histocompatibility antigen, DRB1-8 beta chain
VASP
Ena/VASP proteins
p-Y188,Y199-CD3E
p-S552-CARD11
HLA class II histocompatibility antigen, DRB1-1 beta chain
TRBC1
MALT1
H2O
IKBKG
p-Y753,Y759,Y1217-PLCG2
SCF-beta-TRCP
CD4
HLA class II histocompatibility antigen, DQ
K63polyUb
NCK1
H2O
p-5Y-LAT
BTRC
ATP
HLA class II histocompatibility antigen, DRB1-14 beta chain
HLA class II histocompatibility antigen, DRB1-7 beta chain
CD3G
ITK:p-Y113,128,145-SLP-76:GADS:LAT
BCL10
ATP
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor
PTPRJ
HLA class II histocompatibility antigen, DP alpha chain precursor
p-Y394-LCK
HLA class II histocompatibility antigen, DR-1 beta chain precursor
HLA class II histocompatibility antigen, DQ beta 2 chain
ITK
HLA class II histocompatibility antigen, DRB1-12 beta chain
HLA class II histocompatibility antigen, DRB1-1 beta chain
ATP
PI(3,4,5)P3
p-5Y-LAT
HLA class II histocompatibility antigen, DRB1-10 beta chain
TCRB
HLA class II histocompatibility antigen, DRB1-13 beta chain
TCRA
p-5Y-LAT
ATP
PLCG1
PSMD7
CD3G
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor
NFKB1(1-433)
HLA class II histocompatibility antigen, DRB1-13 beta chain
p-Y160,Y171-CD3G
HLA class II histocompatibility antigen, DQ beta 2 chain
p-Y90,T538,S676,S695-PRKCQ
HLA class II histocompatibility antigen, DRB1-10 beta chain
p-S177,S181-IKKB:IKKA:pUb-NEMO
HLA class II histocompatibility antigen, DRB1-15 beta chain
HLA class II histocompatibility antigen, DRB1-12 beta chain
HLA class II histocompatibility antigen, DRB1-10 beta chain
ADP
PAK2
ATP
p-Y771,Y783,Y1254-PLCG1
HLA class II histocompatibility antigen, DRB1-7 beta chain
PSME4
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor
HLA class II histocompatibility antigen, DQ
ENAH
p-Y188,Y199-CD3E
ZAP-70 and ITK
tyrosine kinases
TRAV19
p-S552-CARD11
TRBC1
HLA class II histocompatibility antigen, DRB1-15 beta chain
HLA class II histocompatibility antigen, DRB1-1 beta chain
Ub-352-UBC(305-380)
T-cell receptor alpha chain V region PY14 precursor
HLA class II histocompatibility antigen, DP alpha chain precursor
HLA class II histocompatibility antigen, DRB1-15 beta chain
PSMD13
PTPRC
CD4
Ub-48-UBB(1-76)
Antigen
HLA class II histocompatibility antigen, DRB1-14 beta chain
HLA class II histocompatibility antigen, DRB1-1 beta chain
LCP2
HLA class II histocompatibility antigen, DR-1 beta chain precursor
HLA class II histocompatibility antigen, DQ
NCK1
p-S177,S181-IKBKB
HLA class II histocompatibility antigen, DRB1-16 beta chain
PI(4,5)P2
HLA class II histocompatibility antigen, DQ
SKP1
Antigen
CHUK
TAB2/TAK1 complex
RELA
p-Y113,128,145-LCP2
TRBV12-3
K48-Ub
RELA
HLA class II histocompatibility antigen, DRB1-12 beta chain
HLA class II histocompatibility antigen, DR beta 5 chain
HLA class II histocompatibility antigen, DP alpha chain precursor
TRAC
HLA class II histocompatibility antigen, DP alpha chain precursor
PLCG1
p-Y315,Y493-ZAP70
ADP
TRBV12-3
ATP
HLA class II histocompatibility antigen, DR-1 beta chain precursor
HLA class II histocompatibility antigen, DQ
HLA class II histocompatibility antigen, DR beta 5 chain
HLA class II histocompatibility antigen, DR beta 5 chain
DAGs
p-Y160,Y171-CD3G
p-Y160,Y171-CD3G
UBE2D1
p-BCL10
p-Y160,Y171-CD3G
CD3G
p-Y315,Y493-ZAP70
NFKB1(1-433)
CD247-1
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor
HLA class II histocompatibility antigen, DP
PSMA3
HLA class II histocompatibility antigen, DRB1-4 beta chain
LAT
PDK1:PIP2,PIP3
TRBV12-3
Antigen-bearing MHC
Class II : TCR
complex:CD4:Lck
p-5Y-LAT
p-Y90-PKC-theta:DAG
GRAP2
FYB
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor
p-Y394-LCK
p-Y149,Y160-CD3D
HLA class II histocompatibility antigen, DR beta 4 chain
PI(3,4)P2
HLA class II histocompatibility antigen, DRB1-4 beta chain
p-Y394-LCK
HLA class II histocompatibility antigen, DQ
TCRA
HLA class II histocompatibility antigen, DRB1-7 beta chain
Ub-48-UBC(1-76)
PSMA8
p-6Y-CD247
FYB
TRBV12-3
p-Y394-LCK
HLA class II histocompatibility antigen, DR alpha chain precursor
p-Y317-PAG1
PSME3
HLA class II histocompatibility antigen, DRB1-11 beta chain
PI(3,4,5)P3
HLA class II histocompatibility antigen, DRB1-8 beta chain
PI3K
HLA class II histocompatibility antigen, DRB1-15 beta chain
TRAC
HLA class II histocompatibility antigen, DRB1-8 beta chain
TRAV19
HLA class II histocompatibility antigen, DRB1-16 beta chain
HLA class II histocompatibility antigen, DRB1-10 beta chain
HLA class II histocompatibility antigen, DP alpha chain precursor
CUL1
GRAP2
p-Y113,128,145-LCP2
p-Y188,Y199-CD3E
ATP
DAGs
p-Y113,128,145-LCP2
GADS:p-5Y-LAT
EVL
NCK1
TRBC1
TAB2
TCRB
HLA class II histocompatibility antigen, DR beta 5 chain
PI(3,4,5)P3
PSMB5
TRBC1
DAGs
HLA class II histocompatibility antigen, DR-1 beta chain precursor
HLA class II histocompatibility antigen, DRB1-14 beta chain
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor
HLA class II histocompatibility antigen, DRB1-12 beta chain
TRBV12-3
CSK
TCRA
Ub-656-UBC(609-684)
PI(3,4,5)P3
HLA class II histocompatibility antigen, DR beta 5 chain
p-5Y-LAT
HLA class II histocompatibility antigen, DRB1-13 beta chain
ATP
PSMC5
HLA class II histocompatibility antigen, DRB1-4 beta chain
PIK3CA
HLA class II histocompatibility antigen, DR alpha chain precursor
HLA class II histocompatibility antigen, DQ
HLA class II histocompatibility antigen, DP
PLCG1
HLA class II histocompatibility antigen, DQ beta 2 chain
phosphorylated
PLC-gamma1 bound to
SLP-76
PIK3CA
TAK1/TAB2 complex
bound to TRAF6/CBM
complex
PI(3,4)P2
p-Y90-PRKCQ
p-6Y-CD247
p-Y113,128,145-LCP2
I(1,4,5)P3
p-S552-CARD11
PDPK1
TRAC
CD4
HLA class II histocompatibility antigen, DRB1-10 beta chain
CARMA1 trimer
MALT1 trimer bound
to Bcl10 and CARMA1
trimer
ATP
HLA class II histocompatibility antigen, DR beta 5 chain
CD4
PSMD11
HLA class II histocompatibility antigen, DP
PI(3,4,5)P3
phosphorylated
PLC-gamma1 bound to
LAT
PSMA5
PLCG1
ADP
HLA class II histocompatibility antigen, DRB1-7 beta chain
PI(3,4)P2
HLA class II histocompatibility antigen, DQ beta 2 chain
IkB(alpha):NF-kB
complex
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor
HLA class II histocompatibility antigen, DRB1-13 beta chain
HLA class II histocompatibility antigen, DR-1 beta chain precursor
CD3D
UBE2N:UBE2V1
ADP
HLA class II histocompatibility antigen, DRB1-1 beta chain
PDPK1
p-Y113,128,145-LCP2
PI(3,4,5)P3
p-BCL10
HLA class II histocompatibility antigen, DQ beta 2 chain
HLA class II histocompatibility antigen, DQ
TRAV19
Ub-276-UBC(229-304)
HLA class II histocompatibility antigen, DQ
PSMA7
Bcl10 trimer bound
to CARMA1 trimer
PI(3,4)P2
p-SLP-76:NCK:PAK
CD247-1
PI(3,4,5)P3
CD4
Antigen-bearing MHC
Class II :TCR
complex:CD4: Lck
phosphorylated at
Tyr394
TRBC1
TCRB
HLA class II histocompatibility antigen, DP
p-S552-CARD11
GRAP2
p-S552-CARD11
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor
Antigen-bearing
MHC
Class
II
:
TCR
complex:CD4:p-Lck(Y505)
LCP2
PSMF1
PDPK1
IKBKG
PTPN22
Ub-200-UBB(153-228)
HLA class II histocompatibility antigen, DRB1-14 beta chain
RELA
HLA class II histocompatibility antigen, DQ beta 2 chain
CDC34
TRAF6
CHUK
Ub-TRAF6 trimer
bound to CBM
complex
HLA class II histocompatibility antigen, DRB1-14 beta chain
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor
ADP
PIK3R1
p-Y113,128,145-LCP2
PLCG1:p-5Y-LAT
HLA class II histocompatibility antigen, DRB1-7 beta chain
Antigen
p-Y317-PAG1
HLA class II histocompatibility antigen, DQ
H2O
PDPK1
PI(4,5)P2
HLA class II histocompatibility antigen, DRB1-4 beta chain
ZAP-70 bound to
phosphorylated ITAM
motifs
HLA class II histocompatibility antigen, DRB1-10 beta chain
TCRB
PSMA4
MALT1
HLA class II histocompatibility antigen, DRB1-16 beta chain
PSMB1
HLA class II histocompatibility antigen, DR alpha chain precursor
PSMD6
Antigen-bearing MHC
Class II :TCR
complex:CD4: Lck
phosphorylated at
Tyr394
MALT1
p-5Y-LAT
p-5Y-LAT
HLA class II histocompatibility antigen, DQ
PSMB3
PI(4,5)P2
TRBV12-3
HLA class II histocompatibility antigen, DQ beta 2 chain
HLA class II histocompatibility antigen, DRB1-11 beta chain
NFKB1(1-433):RELA
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor
T-cell receptor alpha chain V region PY14 precursor
HLA class II histocompatibility antigen, DR alpha chain precursor
PI(3,4)P2
PTPN22
ADP
PTPN22:CSK
NFKB1(1-433)
HLA class II histocompatibility antigen, DRB1-12 beta chain
HLA class II histocompatibility antigen, DRB1-11 beta chain
TCRB
RELA
RELA
HLA class II histocompatibility antigen, DRB1-7 beta chain
p-Y113,128,145-SLP-76:GADS:LAT
ZAP70
HLA class II histocompatibility antigen, DRB1-16 beta chain
HLA class II histocompatibility antigen, DRB1-16 beta chain
HLA class II histocompatibility antigen, DRB1-15 beta chain
Ub-504-UBC(457-532)
TRAV19
EVL
PSMD3
HLA class II histocompatibility antigen, DRB1-8 beta chain
p-Y63,Y79,Y110-TRAT1
TCRB
HLA class II histocompatibility antigen, DRB1-1 beta chain
PSMD9
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor
TRBC1
NFKB1(1-433)
PI(3,4)P2
Active PKC theta
bound to DAG
FBXW11
TCRA
p-5Y-LAT
PIK3CB
HLA class II histocompatibility antigen, DRB1-11 beta chain
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor
PIP3 activates AKT
signaling
HLA class II histocompatibility antigen, DRB1-15 beta chain
PKC-theta (open):
DAG
HLA class II histocompatibility antigen, DQ
HLA class II histocompatibility antigen, DRB1-8 beta chain
HLA class II histocompatibility antigen, DP alpha chain precursor
HLA class II histocompatibility antigen, DRB1-13 beta chain
CD4
p-Y149,Y160-CD3D
PSMA6
K63polyUb
ADP
MALT1 trimer
p-BCL10
PAK1,2,3
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor
PSMD2
p-Y149,Y160-CD3D
p-S552-CARD11
p-Y771,Y783,Y1254-PLCG1
PSMD10
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor
p-SLP-76:ADAP:Ena/VASP
PI(3,4)P2
MALT1
PDPK1
HLA class II histocompatibility antigen, DRB1-11 beta chain
HLA class II histocompatibility antigen, DQ
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor
PRKCQ
PI(3,4)P2
HLA class II histocompatibility antigen, DR alpha chain precursor
PSMC3
p-BCL10
HLA class II histocompatibility antigen, DQ
ADP
HLA class II histocompatibility antigen, DQ
HLA class II histocompatibility antigen, DRB1-8 beta chain
HLA class II histocompatibility antigen, DP
ENAH
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor
Ub-428-UBC(381-456)
HLA class II histocompatibility antigen, DR beta 5 chain
PSMB10
p-Y160,Y171-CD3G
HLA class II histocompatibility antigen, DRB1-15 beta chain
CARMA1 bound to PDK1
HLA class II histocompatibility antigen, DRB1-8 beta chain
HLA class II histocompatibility antigen, DRB1-13 beta chain
HLA class II histocompatibility antigen, DQ beta 2 chain
CARD11
HLA class II histocompatibility antigen, DRB1-11 beta chain
GRAP2
HLA class II histocompatibility antigen, DRB1-4 beta chain
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor
PSMD4
PSMC6
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor
HLA class II histocompatibility antigen, DRB1-1 beta chain
p-6Y-CD247
HLA class II histocompatibility antigen, DQ
HLA class II histocompatibility antigen, DR beta 4 chain
p-S552-CARD11
HLA class II histocompatibility antigen, DQ
PLC-gamma1 bound to
LAT or SLP-76
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor
HLA class II histocompatibility antigen, DRB1-13 beta chain
HLA class II histocompatibility antigen, DP
UBE2N
Activated ZAP-70
p-Y493-ZAP70
HLA class II histocompatibility antigen, DRB1-4 beta chain
PRKQC closed
conformation
PIK3R1
CD3E
WAS
TRAC
CD3E
PI(3,4)P2
HLA class II histocompatibility antigen, DR beta 4 chain
CSK
ITK
p-Y149,Y160-CD3D
HLA class II histocompatibility antigen, DR-1 beta chain precursor
HLA class II histocompatibility antigen, DR alpha chain precursor
T-cell receptor alpha chain V region PY14 precursor
TRAC
p-Y113,128,145-LCP2
HLA class II histocompatibility antigen, DR beta 4 chain
MALT1
H2O
TRBV12-3
PDPK1
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor
PSME1
PSMB7
ADP
Ub-48-UBA52(1-76)
HLA class II histocompatibility antigen, DP alpha chain precursor
p-SLP-76:ADAP
PDPK1
CARD11
PI(3,4,5)P3
CSK
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor
HLA class II histocompatibility antigen, DP alpha chain precursor
HLA class II histocompatibility antigen, DRB1-11 beta chain
HLA class II histocompatibility antigen, DRB1-7 beta chain
p-Y505-LCK
p-Y771,Y783,Y1254-PLCG1
CD3E
ADP
Antigen
T-cell receptor alpha chain V region PY14 precursor
p-S177,S181-IKKB:IKKA:NEMO
PI(3,4)P2
PDPK1
UBE2N:UBE2V1
p-SLP-76:NCK1:WASP
p-4Y-PLCG1
p-Y113,128,145-LCP2
p-S552-CARD11
PAK1
p-Y113,128,145-LCP2
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor
HLA class II histocompatibility antigen, DRB1-16 beta chain
HLA class II histocompatibility antigen, DQ
p-Y394-LCK
TRBC1
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor
p-Y113,128,145-LCP2
p-SLP-76:NCK1
PI(3,4)P2
TCRB
HLA class II histocompatibility antigen, DRB1-14 beta chain
Activated CARMA1
K48PolyUb-K21,22-p-S32,S36-IkBA
TCRA
p-PLCG
NFKB1(1-433)
ATP
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor
PSMD5
p-Y188,Y199-CD3E
CD3G
PAK2
K63polyUb-TRAF6
p-4Y-PLCG1
ADP
ADP
PSMC4
TRAV19
HLA class II histocompatibility antigen, DR alpha chain precursor
IKBKB
ATP
PI(3,4,5)P3
PSME2
TRAF6
Pi
PI(3,4,5)P3
H2O
TCRB
TCRA
HLA class II histocompatibility antigen, DQ
HLA class II histocompatibility antigen, DRB1-10 beta chain
CD3E
TRBV12-3
PSMD1
DAGs
ATP
TRAV19
p-5Y-LAT
p-BCL10
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex
CD101
PAK1
HLA class II histocompatibility antigen, DQ
p-BCL10
HLA class II histocompatibility antigen, DRB1-15 beta chain
PSMB2
UBE2D2,UBE2D1,(CDC34)
PI(3,4,5)P3
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor
HLA class II histocompatibility antigen, DRB1-14 beta chain
NFKBIA
TRAC
Phosphorylated Bcl10
bound to CARMA1 and
RIP2
ATP
p-S32,36-IkB-alpha:NF-kB complex
Ub-200-UBC(153-228)
HLA class II histocompatibility antigen, DRB1-13 beta chain
UBE2D2
HLA class II histocompatibility antigen, DR alpha chain precursor
TRAV19
p-5Y-LAT
Bcl10 bound to
CARMA1
T-cell receptor alpha chain V region PY14 precursor
HLA class II histocompatibility antigen, DR alpha chain precursor
26S proteasome
Ub-124-UBB(77-152)
p-BCL10
DAGs
HLA class II histocompatibility antigen, DRB1-4 beta chain
phospho tyrosine
ZAP-70
p-Y149,Y160-CD3D
HLA class II histocompatibility antigen, DRB1-10 beta chain
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor
PI(3,4,5)P3
p-6Y-CD247
CD4
CD247-1
p-Y394-LCK
ADP
Antigen
GRAP2
HLA class II histocompatibility antigen, DQ
HLA class II histocompatibility antigen, DQ
HLA class II histocompatibility antigen, DRB1-12 beta chain
HLA class II histocompatibility antigen, DRB1-14 beta chain
p-Y188,Y199-CD3E
TRAV19
HLA class II histocompatibility antigen, DP
CD4
TRAC
PDPK1
p-S177,S181-IKBKB
TCRA
HLA class II histocompatibility antigen, DQ
PSMC2
HLA class II histocompatibility antigen, DR beta 4 chain
PLCG1:p-3Y-SLP-76:Gads:LAT
PIK3CB
p-S32,S36-NFKBIA
HLA class II histocompatibility antigen, DRB1-7 beta chain
PSMD8
K63polyUb-TRAF6
HLA class II histocompatibility antigen, DRB1-4 beta chain
ZAP70
VASP
GRAP2
PDPK1
HLA class II histocompatibility antigen, DR-1 beta chain precursor
Csk:p-PAG
INPP5D
p-Y113,128,145-LCP2
HLA class II histocompatibility antigen, DQ
GRAP2
Antigen-bearing MHC
Class II: TCR with
phosphorylated
ITAMs:CD4
p-Y63,Y79,Y110-TRAT1
PI(3,4)P2
CD3D
p-Y394-LCK
p-5Y-LAT
CD3D
TCRA
PSMA2
Activated PLC gamma1
bound to PIP2
HLA class II histocompatibility antigen, DRB1-12 beta chain
HLA class II histocompatibility antigen, DRB1-1 beta chain
HLA class II histocompatibility antigen, DR beta 5 chain
UBE2V1
HLA class II histocompatibility antigen, DQ
NCK1
HLA class II histocompatibility antigen, DRB1-4 beta chain
HLA class II histocompatibility antigen, DRB1-10 beta chain
p-Y113,128,145-LCP2
PSMB6
GRAP2
T-cell receptor alpha chain V region PY14 precursor
TAB2
PDPK1
HLA class II histocompatibility antigen, DRB1-15 beta chain
T-cell receptor alpha chain V region PY14 precursor
HLA class II histocompatibility antigen, DR-1 beta chain precursor
Pi
FYB
HLA class II histocompatibility antigen, DP
PI(3,4,5)P3
CHUK:IKBKB:IKBKG
PI(4,5)P2
ATP
NFKB1(1-433):RELA
PSMB11
PSMA1
Antigen
TCRB
PSMB4
T-cell receptor alpha chain V region PY14 precursor
p-S552-CARD11
HLA class II histocompatibility antigen, DRB1-16 beta chain
HLA class II histocompatibility antigen, DQ
PSMD14
Antigen
PIK3R2
HLA class II histocompatibility antigen, DR beta 4 chain
SHFM1
LCK
PSMB9
Antigen
HLA class II histocompatibility antigen, DR beta 4 chain
HLA class II histocompatibility antigen, DR beta 4 chain
PTEN
CD247-1
PIP3, PI(3,4)P2
ADP
Phosphorylated
PLC-gamma1 bound to
LAT or SLP-76
PI3K bound to TRAT
TRBC1
TRAF6 trimer bound
to CBM complex
HLA class II histocompatibility antigen, DRB1-14 beta chain
PI(3,4)P2
77
7
38, 47, 65
21
21
48, 75
49
60
21
21
61
21
60
21
49
54
21
61, 62
48