RNA Polymerase II Transcription (Homo sapiens)

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256616, 20, 41, 718650680, 8366, 78, 851520, 6623, 33, 846797, 5766, 35, 43, 73136794649, 5666, 7851, 62655, 79627610, 20, 66, 82816628, 34, 42, 52, 60...24, 65791366, 78, 856623, 33, 84679464666, 785050nucleoplasmRTF1 GTF2H3 PABPN1 TCEB1CCNT2 TCEB3C DNA containing RNAPolymerase IIpromoterTAF7 CCNH POLR2E CSTF2T MNAT1 CCNT1 POLR2B RNMTSNRPF TAF12 POLR2B GTF2A1(1-274) ATP GTF2F2 GTF2H1 POLR2G POLR2C GTF2H3 TAF1L CDC73 TAF15 NCBP1 TAF4B POLR2D GTF2H1 IWS1UTP GTP hSLU7 GTF2H2 POLR2F NUDT21 TCEB3CL WDR61 GTF2H5 POLR2F GTP TAF6 TAF4B GTF2A1(275-376) NELFB POLR2C MNAT1 GTF2E1 NUDT21 TAF7L MAGOHB NELFCD POLR2H POLR2E GTF2E1 TAF15 POLR2K CTP GTF2E2 NELFA TCEB3C POLR2I EAF2 p-SUPT5H UTP CDK7 ELL POLR2H NELFE UTP TAF1L TAF13 GTF2A1(1-274) CDK7 GTF2E2 UTP GTF2F2 TBP CSTF1 EAF1 NELFAGTP POLR2J TAF7 CLP1 TAF9 EAF1 TCEB3CL2 p-SUPT5H POLR2H GTF2H2 SUPT6H GTF2H1 GTF2F2 SNRPF MLLT3 GTF2F2 RNGTT PPiGTF2H2 LEO1 template DNA:4 nucleotide transcript hybrid CDC73 WDR61 TAF6 ELL POLR2C POLR2B DNA containing Pol II promoter with transcript with 2 or 3 nucleotides CCNH GTF2E1 GTF2A1(1-274) GTF2A1(1-274) POLR2J hSLU7 THOC3 POLR2D POLR2E GTF2E1 POLR2I U2AF2 CF I - 72 kDa subunit polIIpromoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complexPPiDDX39A TAF11 NELFE POLR2B POLR2L SYMPK GTF2A1(275-376) POLR2H CDK7 NELFCD TAF3 TAF10 SUPT16H ERCC2 POLR2D POLR2C POLR2A AFF4 TCEB3 POLR2C TAF9 THOC6 CF I - 68 kDa subunit NELFCD SRSF1 POLR2K POLR2H upstream intronless mRNA fragment POLR2G CDC40 POLR2G SRSF3 CF I - 68 kDa subunit CPSF4 POLR2A GTP POLR2F IWS1 POLR2D TFIIHGTF2A1(275-376) NCBP1 GTF2F2 POLR2K NELFB template:capped transcript hybrid CDK7 NTPCF I - 68 kDa subunit RNA polymerase IItranscribes snRNAgenesLEO1 POLR2D CTP Elongation complexprior to separationPOLR2F TAF12 POLR2G NTPTAF3 GTF2F1 GTP SRSF11 TAF15 CTP ALYREF GTF2F1 EIF4A3 RBM8A POLR2H POLR2G POLR2D ATPGTF2H2 TAF7 NCBP2 GTF2H3 POLR2C GenericTranscriptionPathwayERCC2 POLR2E TAF10 template DNA:9 nucleotide transcript hybrid U2AF1 MNAT1 TCEB3B TAF1L UTP GTF2A1(1-274) POLR2B POLR2G CDK7 POLR2B CPSF3 CCNH POLR2F ELL POLR2A TCEA1 POLR2G ERCC2 TCEB3CL POLR2C POLR2A UTP TAF9 GTF2A2 U2AF2 template DNA:4-9nucleotidetranscript hybridTAF1L POLR2B POLR2I SNRPE NCBP2 TAF9B TFIIDTAF10 TAF3 THOC5 POLR2F POLR2G p-SUPT5H TAF4 RNGTT POLR2C ERCC2 GTF2H1 TAF5 RNAPolII(hypophosphorylated) complex bound to DSIF proteinp-S5-POLR2A mRNA with spliced exons GTF2H3 GTF2F1 NELFA POLR2I NELFB CTP POLR2D U7 snRNA GTF2F2 TAF15 CTP ATP GTF2H3 POLR2J TAF13 TAF7 GTF2H3 CDK9 p-S5-POLR2A GTF2H4 POLR2D CTDP1SUPT16H ATPTCEB3CL2 ATP POLR2F POLR2F U2AF1L4 POLR2E GTF2B template DNA withfirst transcriptdinucleotide,opened to +8positionIWS1 UTP GTF2F2 CCNH TAF11 TAF7L SRSF7 GTF2E1 GTF2A1(275-376) GTF2H4 GTF2F1 pol II openpre-initiationcomplexGTF2H4 MLLT1 GTF2H1 FIP1L1 ERCC2 TAF10 UTP POLR2F GTF2F1 POLR2E Elongating transcript in processive Pol II mediated elongation p-S2,S5-POLR2A GTF2F2 CTR9 Elongating transcript in processive Pol II mediated elongation PAPOLA GTF2A2 GTF2H5 Mature intronlesstranscript derivedHistonepre-mRNA:CBCcomplexGTF2H5 TFIIHGTF2H4 CCNT1 DDX39B POLR2F GTF2F1 TAF7L GTF2H3 TAF11 TCEB3CL2 GTF2H4 template:capped transcript hybrid POLR2B ERCC3 POLR2F THOC1 TAF9 SNRPB GTF2F2 CDK7 POLR2H PCF11 ERCC2 POLR2A CTP NELFE CTP POLR2L template DNA:11 nucleotide transcript hybrid GTF2F1 NCBP2 SUPT4H1 ERCC2 SNRPG SYMPK CDK7 template DNA:30 nt transcript hybrid POLR2J PAF1 TAF1L SUPT6H POLR2L POLR2L POLR2I GTF2H3 POLR2J SUPT16H TAF5 THOC7 p-S2,S5-POLR2A p-SUPT5H LEO1 POLR2E POLR2G CstFAborted elongationcomplex afterarrestTAF9 Pol II transcriptioncomplex containingextruded transcriptto +30TAF12 SLBP POLR2I CDK9TCEB3 TAF1L TAF7L ERCC2 p-S5-POLR2A GTF2H1 TCEB3CL2 SUPT4H1 POLR2C TCEB3CL CDK7 GTF2H3 POLR2J NELFE POLR2D Pol II transcriptioncomplex with (ser5)phosphorylated CTDcontaining extrudedtranscript to +30TAF3 TAF2 POLR2I POLR2A Capped IntronlessHistonepre-mRNA:CBC:ZFP100ComplexSNRPB POLR2E SRSF5 POLR2H PAF1 TAF15 CTDP1 CLP1 POLR2G GTF2H5 TCEB3 POLR2G DDX39A GTF2H1 SNRPF GTF2F2 CPSF7 TAF4 GTP MNAT1 CTDP1POLR2A POLR2D LEO1 UTP TAF1 GTF2H4 GTF2H4 PABPN1 U2AF1 ERCC2 TAF9B TAF5 CTDP1 GTF2H1 GTF2F2 CPSF2 TCEB3CL LSM10 NTPPOLR2G MLLT1 ERCC2 RNGTTDNA containing RNA Polymerase II promoter GTF2A2 POLR2F GTF2H2 TAF1L TAF1 POLR2B POLR2D TAF9B POLR2L POLR2I RBM8A POLR2A POLR2I SNRPD3 POLR2K POLR2J POLR2F ERCC2 POLR2I POLR2L TAF15 POLR2H NTPEAF2 NELFA POLR2H POLR2D GTF2F1 GTF2F1 CCNH MLLT1 GTF2B UPF3B Pol II PromoterEscape ComplexCCNK POLR2D CDK7 POLR2G PAPOLA POLR2L p-S5-POLR2A GTF2A1(275-376) TAF6 TFIIFERCC2 GTF2F2 THOC6 ATP CPSF3 NUDT21 FACT complexPOLR2G EAF2 POLR2H ATP SUPT4H1 TCEB2 AFF4 CTDP1 Elongation complexwith separated anduncleavedtranscriptPOLR2C TCEB3 PAF1 GTF2F2 TAF4 CCNT1 POLR2L TCEB1 POLR2L TCEB3CL GTF2H2 TAF9B CCNT2 MNAT1 TAF9 TAF4 GTF2F2 CCNH SUPT16H CDK7 GTF2H5 ERCC2 NELFA POLR2H CLP1 EAF1 TAF4B TAF5 NELFE Elongin B:C complexTAF7 POLR2H ELL pol IIpromoter:TFIIDcomplexCDK7 GTF2H1 p-S2,S5-POLR2A GTF2A1(275-376) CTP CTDP1 RTF1 MLLT1 TAF15 CCNH CDK7 GTF2H1 TAF7L GTF2H4 POLR2G TAF11 TCEB2 ZNF473 POLR2E NELFBZNF473 MNAT1 POLDIP3 POLR2L GTF2E1 MLLT1 GTF2H1 POLR2B TBP TAF5 TAF11 GTF2H5 TCEB2 SRSF9 POLR2F POLR2I CTP TAF10 NTPNELFA POLR2L ERCC2 RTF1 pol II transcriptioncomplex containing4 nucleotide longtranscriptCPSF7 WDR33 CDC73 MNAT1 POLR2J POLR2J ZC3H11A CCNH GTF2H1 TCEB3 ERCC3 MLLT3 MLLT3 POLR2H TAF9 TAF6 SNRPE CSTF1 CTR9 TAF6 ERCC3 POLR2F ERCC2 MNAT1 SplicedmRNA:CBC:EJC:TREXPOLR2J GTF2A2 TAF9B TAF2 POLR2G POLR2H CDK9 POLR2K p-S2,S5-POLR2A MAGOH POLR2L TAF13 POLR2I NCBP2 POLR2C NCBP1 POLR2J GTF2H1 PPiNELFE POLR2I SRSF2 ZC3H11A TAF11 SUPT4H1 MNAT1 NCBP2 TAF12 TAF9B CASC3 POLR2E WDR33 CPSF7 CCNT1 THOC2 CPSF7 CPSF1 POLR2E GTF2H5 NCBP2 SUPT16H POLR2D POLR2J p-SUPT5H EAF2 TAF1 POLR2E SRSF9 TAF9B GTP CF IINCBP2 POLR2F TAF5 CCNH p-S5-POLR2A NCBP1 CCNT2 EAF1 P-TEFb complexGTF2H5 GTF2F1 LSM10 LSM10 TBP ELL NELFCDPOLR2C POLR2H MNAT1 POLR2L POLR2I template DNA:30 nt transcript hybrid TAF3 TCEB3CL GTF2F2 GTF2F2 GTF2H5 POLR2H RNMT TAF6 GTF2A2 POLR2L TAF7L THOC5 POLR2K POLR2F POLR2A POLR2F TAF11 GTF2H2 POLR2G TAF4B TAF4 AFF4POLR2J TAF10 TAF12 CCNT2 GTF2H1 GTF2A1(1-274) POLR2C POLR2L CCNT1 TBP TCEB1 POLR2B template DNA with first transcript dinucleotide, opened to +8 position TAF10 POLR2I POLR2L capped pre-mRNA TAF4B SUPT4H1 TCEB3C POLR2I GTF2E1 TCEA1POLR2J TAF12 POLR2J WDR33 CCNT1 NCBP2 CDK9 POLR2E EAF1 POLR2L MNAT1 POLR2H TCEB3CL2 ERCC3 TCEB3CL2 GTF2F1 TCEB3C TAF11 TBP GTF2A2 GTF2H4 POLR2B AFF4 TAF2 GTF2F2 RTF1 POLR2B ERCC2 CTP TAF4B POLR2E CCNT2 DNA containing RNA Polymerase II promoter POLR2G template DNA:30 nt transcript hybrid GTF2H4 POLR2A TAF4B POLR2C p-SUPT5H PAF1 POLR2C POLR2C Elongin ComplexGTF2A1(1-274) CPSF1 EIF4A3 SUPT4H1 POLR2G Elongating transcript in processive Pol II mediated elongation POLR2A TAF9B GTF2H4 TAF11 EAF2 POLR2L Elongin ANCBP2 GTP CDK7 mRNA 3'-end cleavagefactorCCNK CCNT1 p-SUPT5H GTF2F2 POLR2B NCBP1 CDK7 Intronless Histone pre-mRNA CDK7 TCEA1 NELFB p-S2,S5-POLR2A POLR2H CPSF3 GTF2H5 TAF13 GTF2F1 CASC3 PPiPCF11 GTF2H3 GTF2H5 POLR2D NELFA CDC73 WDR61 CDC73 POLR2L ATP TAF3 TCEB2 TAF3 NCBP1 SSRP1 GTF2A1(1-274) GTF2H1 PPiMNAT1 TAF11 GTF2E2 CTR9 CE:Pol II CTD:Spt5complexTAF12 MNAT1 p-SUPT5H ERCC3 ATP POLR2K NCBP1 POLR2K NELFB CTDP1 CPSF4 POLR2L NTPp-S2,S5-POLR2A ERCC3 CSTF2 POLR2E POLR2F POLR2B TAF6 POLR2C ERCC3 TCEB3C WDR61 SYMPK GTF2H2 MNAT1 GTF2H2 TAF13 POLR2E POLR2J PABPN1 POLR2L TAF4B TAF11 ATP POLR2K POLR2F GTF2F2 TFIIHTCEB3 POLR2C ERCC3 CTR9 POLR2C p-SUPT5H POLR2K NELFA TAF7 SUPT4H1 GTF2F1 POLR2K GTF2A2 TAF3 Elongating transcript prior to cleavage cappedpre-mRNA:CBC:RNAPol II(phosphorylated)complexPOLR2J TAF10 GTF2H5 GTF2F2 GTF2A1(275-376) ATP TAF6 CCNK TAF9 NELFE POLR2G POLR2J GTF2H3 GTF2F1 ERCC2 ERCC2 MNAT1 POLR2D SUPT6H POLR2C POLR2E TAF3 TAF13 GTF2H4 POLR2K CDC73 TAF9B SNRPG ALYREF POLR2J POLR2I RTF1 POLR2H GTF2A1(275-376) GTF2H2 Capped intronless pre-mRNA POLR2L TAF5 ATP POLR2E POLR2E TAF1 ELLU7 snRNP:ZNF473POLR2J GTF2E1 MLLT3 TCEB3CL SRRM1 GTF2H2 PAF1CGTF2E1 POLR2F TAF7 POLR2E TAF4 GTF2H2 TAF1L SRRM1 Pol II initiationcomplexp-S2,S5-POLR2A POLR2I TBP GTP CHTOP CTR9 GTF2H3 CLP1 GTF2F1 TAF1L TAF4B POLR2G UTP POLR2B CTP template DNA:30 nt transcript hybrid CSTF3 ERCC3 TAF2 TAF4 TCEB3 TAF7 ATP SRSF4 GTF2E1 RNPS1 Aborted earlyelongation complexTAF1 POLR2I POLR2E SUPT6H GTF2F1 CPSF2 p-SUPT5H PCF11 ERCC3 EAF1 CTDP1 SSRP1 RTF1 TAF12 SRSF5 POLR2B CTP POLR2H MNAT1 POLDIP3 POLR2B SRSF6