Integration of energy metabolism (Homo sapiens)

From WikiPathways

Jump to: navigation, search
66, 77, 14112, 24, 71, 110, 117...6, 25, 7934, 11559, 86, 90, 152, 166...5, 90, 93, 1691, 14, 26, 28, 45...15, 90, 145, 148, 16934, 783, 9, 10, 24, 37...29, 34, 59, 12319, 34, 74, 82, 132...32, 53, 54, 60, 65...1081, 21, 23, 41, 51...5, 27, 63, 67, 90...21, 59, 89, 140381573829, 34, 35, 59, 64...4, 15, 61, 90, 138...22, 31, 58, 92, 96...16, 52, 11320, 21, 59, 89, 103...59, 69, 90, 144, 16959, 90, 101, 136, 144...445, 27, 63, 67, 90...75, 15248, 90, 111, 16933, 55, 68, 7036, 42, 43, 98, 124...21, 59, 86, 89, 119...135, 14913, 5011, 21, 46, 59, 89...8, 122, 147, 15820, 21, 40, 56, 59...4, 53, 90, 152, 166...57, 62, 14918, 39, 94, 136, 143...57, 62446610934, 59, 1067, 73, 76, 1679514221, 59, 89, 1409557, 6217secretory granulenucleoplasmmitochondrial matrixcytosolendoplasmic reticulum lumenATPGNGT2 GNG7 CACNA1D Mg2+:ADPADIPOQ trimer:ADIPORdimersADCY9 PRKAR2B MLXIPLGNA15 FFAR1 p-S568-MLXIPLRGZ Adenylyl cyclase(pancreatic betacell)GNG2 KCNC2 GNG8 GNG13 ITPR1 GNAQ cAMP CACNB2 Potassium Channel,open (pancreaticbeta cell)ARL2:GTP:ARL2BPPRKAR1B ADRA2C GNAI1 PRKAB2 4xHC-INS(90-110) GLUT1,2PRKACA GNGT1 GNG12 ADIPOQ trimerGNB4 PRKACB GNG4 ADR, NAdGNG4 ADIPOR1 ADCY6 PKA catalyticsubunitGLP-1R:Heterotrimeric G(s):GDPATP SYT5 STK11GNGT1 GNG11 OLEA KCNJ11tetramer:ABCC8:Mg2+:ADP tetramerArgN-GCG(98-127) CACNB3 DAG GNGT1 GNG11 ADCY6 ADPATPcAMP:PKA:AKAP79:IQGAP1 ComplexGNGT1 GNG11 ATPABCC8 GNGT2 CACNA1D ADPGNGT1 GNA15 GNG13 cAMP GNB5 GNB1 SNAP25GNB3 AHCYL1:NAD+:ITPR1:I(1,4,5)P3 tetramerGNAS1 PLCB2 CACNA2D2(19-1150) GNB5 ATPPotassiumvoltage-gatedchannels (betacell, open)CACNA1A RAPGEF3:cAMP complexGNB5 GNAI1 GNAS1 cAMP ATPADPGNG8 ARL2 ABCC8 N72S KCNJ11 PPP2R1A GTP INS(57-87)GNGT1 GNB5 G-protein with G(s)alpha:GDPGuanine nucleotide-binding protein gamma subunit Pentadecanoic acid GNG3 Voltage-gatedCalcium ChannelsType Cav1 (open)GNAS2 ACCPALM GNAS2 ADRA2A CACNB3 GNA15 PRKACB GLP-1:GLP-1R:Heterotrimeric G(s):GTPAHCYL1 ADCY8 GNA11 Guanine nucleotide-binding protein beta subunit GTP TALDO1 dimerITPR1 GNB4 Guanine nucleotide-binding protein beta subunit GNB2 GTPCore SNARE ComplexGNG10 PRKAA2 GNB1 GDP GNAQ GNG8 GDPPRKCA GNG8 PRKAR1A G-alpha(i,o):GTP:G-beta:G-gammacAMP ATPNAd PRKAG2 ADIPOR2 ACLYADP phosphoPFKFB1 dimerGCGRCACNB2 GNG10 KCNG2 GNG7 ITPR3 Ca-channel (open)GNB2 ACACB G-alpha(s):GTP:G-beta:G-gammaArgN-GCG(98-127) PPP2CA GNG4 Guanine nucleotide-binding protein beta subunit GNG5 SLC2A1 Adenylate cyclase(Mg2+ cofactor)ITPR1 GNB4 GNG5 ADCY5 Ca-channel (closed)GLP-1 (7-37) GNG5 GNG3 RAP1A:GDPPPP2R1B GNG2 CACNA1C ADRA2A,C:ADR,NAdGNG11 KCNS3 GNB5 GTP GNG12 GNG8 PPP2CB PRKAR1A GNG7 MARCKSITPR2 GDPGNB3 PALM K+ARL2:GTPPPP2R5D GNB1 ADPPLCB3 ADPI(1,4,5)P3 G-alpha(i,o):GDP:Gbeta:G gammaGNG10 ITPR3 G-alpha(q)11,14,15,Q:GTPITPR2 GNA15 Potassium Channel,closed (pancreaticbeta cell)KCNG2 GNB5 SLC25A4 GNG12 ADCY6 GNAI2 GNB3 CACNB3 Activated AMPKheterotrimerADCY5 GNB3 ADCY5 KCNJ11 SLC25A5,6 dimersGNB1 cAMPZn2+PP2A-ABdeltaCcomplexTKT dimerPiITPR3 CACNA1D GNG13 G-beta:G-gamma(candidates)TALDO1G-alpha(q)11,14,15,Q:G-beta:G-gammaADP GLP1R ITPR3 PRKACA GNB3 GDP GNG11 GNG4 GlcRAP1A:GTPSLC2A2 Fru(6)PGNG10 ADCY6 GNAS1 MLX2xHC-INS(25-54) GNB2 GTP G-alpha(i,o):GTPadenosine5'-monophosphateInactivePP2A-ABdeltaCcomplexChREBP:MLXPRKACG STXBP1SYT5GNG3 PRKACG ADCY6 G alpha(s):GTP:AdenylatecyclaseATPGuanine nucleotide-binding protein gamma subunit GNG10 GNB3 GNB3 VAMP2RAPGEF4:cAMP ComplexPPiGNB1 G-alpha(q)11,14,15,Q:GDP:G-beta:G-gammaPRKAR2B GLP-1 (7-37) GNGT2 GNA11 GNG12 GNA14 PRKACG PRKAR1B GNG4 GNB5 GNGT2 SNARE ComplexGNB1 IQGAP1 ARL2 ADR GNG8 ADIPOQ GNB4 GNG5 PPP2CA DAGPFKFB1 I(1,4,5)P3AMPK heterotrimer(inactive)PRKACA K+GNG2 GNG10 Btn-ACACA GNG2 ATPPKLR-1PRKAR1A GNGT2 Mg2+ AKAP5 GLP-1 (7-37) VAMP2 H2OGNB2 PRKACA RAPGEF4CACNA2D2(19-1150) PRKAR2B GDP PPP2R5D Mg2+ OLEA PKA tetramer:4xcAMPGNG3 ATPGNG13 ADPSTX1A ADIPOR1 GNB4 Mg2+ ADCY6 NAd RGZ ABCC8 mutants (PNDM,TNDM2)NAD+ Ca2+AKAP5 GNAI2 GNG4 ABCC8 P132L RAPGEF4 ADRA2A,CADPKCNJ11:ATPtetramer:ABCC8tetramerPRKAR2A GNG3 GLP-1:GLP-1R:Heterotrimeric G(s):GDPIQGAP1 GNG13 GCG(53-81) PLCB1 GNA14 I(1,4,5)P3 SLC25A4GNGT1 PPP2R1A PPP2R5D PRKAB2 ADCY3 ADCY8 GNG8 ABCC8 E382K Guanine nucleotide-binding protein gamma subunit PRKACB ABCC8 R1379C GNB3 ADPSTX1A:STXBP1PI(4,5)P2GNGT2 PPP2CB ADIPOQ GNA11 GNG5 GNG7 p-S196,T666-MLXIPLProtein Kinase C,alpha type: DAGPRKAR1A ITPR2 Fatty acidsp-4S-MARCKSGDPGNG7 ADIPOR dimersGNAS1 GNB2 GNG7 GNB1 GNG3 RAPGEF3 GNB4 mature GLP-1p-S33-PFKFB1 Ca2+SLC25A5 G-beta:G-gamma dimerGTP GLP1R GNG3 ADCY1 PRKACG PLCB1 ARL2BP GNB4 GTP ThDP ARL2:GTP:ARL2BP:SLC25A4Protein Kinase A,catalytic subunitsABCC8 A1185E GNB1 GNG5 ADCY5,6,8:G-alpha(s):GTPGTP KCNS3 GNG11 Mg2+ GNA11 GA3PADCY2 SNAP25 MLX GNA14 PRKAB2 ADR INS(57-87)GNG4 GNGT1 PRKAG2 KCNB1 GTP GNAS1 GNG8 GNG12 GNG12 PKA:AKAP79:IQGAP1ComplexMg2+ KCNB1 GNA14 ATPARL2 I(1,4,5)P3 GCG(53-81)CACNA1C GNB2 GNG12 ADCY4 DDCX Voltage-gatedCalcium Channels(pancreatic betacell)ArgN-GCG(98-127) XY5PRAPGEF3G-beta:G-gamma2xHC-INS(25-54) GDPRAP1A GNG5 ADCY8 GNG2 PLCB3 p-T172-PRKAA2 ABCC8 L213R AMPGNAS1 ARL2BP ADCY7 GNG7 4xHC-INS(90-110) Adenylate Cyclase Vor VIFFAR1 ligands6xInsulin:2xZn2+:Ca2+ (docked granule)ITPR:I(1,4,5)P3tetramerKCNC2 CACNB2 ADCY1 GNG13 PRKAG2 AcChoGTP PP2A-ABdeltaCcomplexPRKACB GNG8 GNB2 GNG13 VAMP2 GNAQ GTPGTP ADCY8 AGPAT1GDPMLXIPL GNG11 ITPR2 GNG5 PFKFB1 dimerITPR1 ADCY2 Zn2+ PRKACB PRKAA2 G alpha (s):GTPGNAS2 PRKAR2B adenosine 5'-monophosphate GLP1R PRKAR2A PKA catalyticsubunitFFAR1ABCC8 GNB2 GNG13 GNAS2 ADPADCY5 GNG12 GNAS1 GNAS2 GDP ADCY5 p-T666-MLXIPLPPP2R1B GNG7 Ca2+Voltage-gatedCalcium ChannelsType Cav1 (closed)GTP PRKACA GNB4 GNAI1 GNG10 Potassiumvoltage-gatedchannels (betacell, closed)GNG3 PPP2CA GDPGDP CACNA1C adenosine 5'-monophosphate GNG8 GNB3 GTP GNG4 PRKAR2A GTPGNAI2 cAMP:PKA regulatorysubunitADCY7 PRKACG ADRA2A GNG3 GNG5 TKT GNG2 GNG10 PLCbeta1,2,3:G-alpha(q):GTPSH7PARL2BP GNB1 GNAS2 PLCB2 GNGT2 GNG2 ITPR1 p-T666-MLXIPLADCY4 GCGR:GCG(53-81)GNG12 CHRM3PPP2CB STX1A GNG11 cAMP PRKCAGNG5 GNG3 TALDO1 ITPR3 GNB1 GCGR PRKAR1B PPP2R1A IP3 receptorhomotetramerR5PH2OSTX1A E4PPLC beta1,2,3GNB4 GTP GDP GNGT2 GNG13 GlcGNG2 GNB2 MuscarinicAcetylcholineReceptorM3:AcetylcholineComplexAdenylate cyclasetype V or VI:G-protein betagamma ComplexGNB3 GNAS2 Ca2+ CACNA1E PPP2R1B FASNGNG13 GTP GNB4 GNG7 ADCY3 GNG10 PiGTPITPR2 Ca2+ GNAS1 PRKAR1B GNG10 ARL2BPARL2 PRKAR2A GNG2 GTPRAP1A STXBP1 GTPGNG11 CHRM3 GNG12 AcCho ADCY5 FFAR1:FFAR1 ligandsInsulinGNB2 ABCC8 L582V GNG4 CACNA2D2(19-1150) ADRA2C GNG4 GTP AMPKheterotrimer:AMPGNB5 GNAQ GNG2 SLC25A6 Pentadecanoic acid ARL2:GTP:ARL2BPGNG11 GNG7 ADIPOR2 ADCY9 GNAS2 DDCX 11585524485, 114108630161458586, 1522, 100521543024, 110, 159100161108685, 114