PluriNetWork (Mus musculus)

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The aim of the PluriNetWork is to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As stated, we intentionally focused on information flow, neglecting reactions, metabolites, intracellular movement of components, and their modifications such as protein phosphorylation Each edge can be seen as direct mechanism between its nodes. For more information, see

Som A, Harder C, Greber B, Siatkowski M, Paudel Y, et al. 2010 The PluriNetWork: An Electronic Representation of the Network Underlying Pluripotency in Mouse, and Its Applications. PLoS ONE 5(12): e15165. doi:10.1371/journal.pone.0015165 http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0015165

The June 2010 PluriNetWork described in the paper can be found at http://www.ibima.med.uni-rostock.de/IBIMA/PluriNetWork/ . The PluriNetWork at WikiPathWays started with the December 2010 version.

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History

View all...
CompareRevisionActionTimeUserComment
89515view10:58, 16 September 2016Mkutmonpubref/ontology tag fix
89475view13:39, 15 September 2016Mkutmonremove space from ontology term id
72003view11:53, 24 October 2013MkutmonChanged Unknown -> GeneProduct for all annotated data nodes
69951view20:43, 11 July 2013MaintBotupdating to 2013 schema
67598view11:31, 26 June 2013DdiglesOntology Term : 'signaling pathway pertinent to development ' added !
41345view00:26, 2 March 2011MaintBotRemoved redundant pathway information and comments
40000view20:36, 22 January 2011AlexanderPicoModified categories
39726view21:54, 14 January 2011AlexanderPicoOntology Term : 'pluripotent stem cell' added !
39722view12:24, 14 January 2011C.HarderModified description
39721view12:21, 14 January 2011C.Harderwe connected the lines to the nodes
39719view12:07, 14 January 2011C.HarderDeleted pathway: updated version
39647view13:08, 6 January 2011C.HarderModified categories
39547view14:00, 18 December 2010C.HarderModified description
39546view13:55, 18 December 2010C.HarderModified description
39545view13:48, 18 December 2010C.HarderNew pathway

External references

Datanodes

View all...
NameTypeDatabase referenceComment
1600029D21RikGeneProduct76509 (Entrez Gene) full name: RIKEN cDNA 1600029D21 gene
Acvr1GeneProduct11477 (Entrez Gene) full name: activin A receptor, type 1
Acvr1bGeneProduct11479 (Entrez Gene) full name: activin A receptor, type 1B / Alk4
Acvr1cGeneProduct269275 (Entrez Gene) full name: activin A receptor, type IC / Alk7
AesGeneProduct14797 (Entrez Gene) full name: amino-terminal enhancer of split
Akt1GeneProduct11651 (Entrez Gene) full name: thymoma viral proto-oncogene 1
ApcGeneProduct11789 (Entrez Gene) full name: adenomatosis polyposis coli
Arid3bGeneProduct56380 (Entrez Gene) full name: AT rich interactive domain 3B (BRIGHT-like)
Atf2GeneProduct11909 (Entrez Gene) full name: activating transcription factor 2
AtrxGeneProduct22589 (Entrez Gene) full name: alpha thalassemia/mental retardation syndrome X-linked homolog (human)
Axin1GeneProduct12005 (Entrez Gene) full name: Axin1
BcamGeneProduct57278 (Entrez Gene) full name: basal cell adhesion molecule
Bmp4GeneProduct12159 (Entrez Gene) full name: bone morphogenetic protein 4
Bmpr2GeneProduct12168 (Entrez Gene) full name: bone morphogenic protein receptor, type II (serine/threonine kinase)
Brca1GeneProduct12189 (Entrez Gene) full name: breast cancer 1
Cabin1GeneProduct104248 (Entrez Gene) full name: calcineurin binding protein 1
CadGeneProduct69719 (Entrez Gene) full name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Carm1GeneProduct74766 (Entrez Gene) full name: coactivator-associated arginine methyltransferase 1
Casp3GeneProduct12367 (Entrez Gene) full name: caspase 3
Ccnd1GeneProduct12443 (Entrez Gene) full name: cyclin D1
Cd44GeneProduct12505 (Entrez Gene) full name: CD44 antigen
Cdc73GeneProduct214498 (Entrez Gene) full name: cell division cycle 73, Paf1/RNA polymerase II complex component, homolog
Cdh1GeneProduct12550 (Entrez Gene) full name: cadherin 1
Cdk2GeneProduct12566 (Entrez Gene) full name: cyclin-dependent kinase 2
Cdk2ap1GeneProduct13445 (Entrez Gene) full name: CDK2 (cyclin-dependent kinase 2)-associated protein 1
Cdkn1aGeneProduct12575 (Entrez Gene) full name: cyclin-dependent kinase inhibitor 1A (P21)
Cdkn2aGeneProduct12578 (Entrez Gene) full name: cyclin-dependent kinase inhibitor 2A
Cdx2GeneProduct12591 (Entrez Gene) full name: caudal type homeo box 2
Cer1GeneProduct12622 (Entrez Gene) full name: cerberus 1 homolog (Xenopus laevis)
Chd4GeneProduct107932 (Entrez Gene) full name: chromodomain helicase DNA binding protein 4
Creb1GeneProduct12912 (Entrez Gene) full name: cAMP responsive element binding protein 1
CrebbpGeneProduct12914 (Entrez Gene) full name: CREB binding protein
Ctbp1GeneProduct13016 (Entrez Gene) full name: C-terminal binding protein 1
Ctbp2GeneProduct13017 (Entrez Gene) full name: C-terminal binding protein 2
CtcfGeneProduct13018 (Entrez Gene) full name: CCCTC-binding factor
Ctnnb1GeneProduct12387 (Entrez Gene) full name: catenin (cadherin associated protein), beta 1
Ctr9GeneProduct22083 (Entrez Gene) full name: Ctr9 (Alco called "SH2 domain-binding protein 1")
CubnGeneProduct65969 (Entrez Gene) full name: cubilin (intrinsic factor-cobalamin receptor)
DazlGeneProduct13164 (Entrez Gene) full name: deleted in azoospermia-like
Ddb1GeneProduct13194 (Entrez Gene) full name: damage specific DNA binding protein 1
DffaGeneProduct13347 (Entrez Gene) full name: DNA fragmentation factor, alpha subunit
DgkaGeneProduct13139 (Entrez Gene) full name: diacylglycerol kinase, alpha
Dhx9GeneProduct13211 (Entrez Gene) full name: DEAH (Asp-Glu-Ala-His) box polypeptide 9
Dkk1GeneProduct13380 (Entrez Gene) full name: dickkopf homolog 1 (Xenopus laevis)
Dnmt1GeneProduct13433 (Entrez Gene) full name: DNA methyltransferase (cytosine-5) 1
Dnmt3aGeneProduct13435 (Entrez Gene) full name: DNA methyltransferase 3A
Dnmt3bGeneProduct13436 (Entrez Gene) full name: DNA methyltransferase 3B
Dnmt3lGeneProduct54427 (Entrez Gene) full name: DNA (cytosine-5-)-methyltransferase 3-like
Dppa4GeneProduct73693 (Entrez Gene) full name: developmental pluripotency associated 4
Dpysl2GeneProduct12934 (Entrez Gene) full name: dihydropyrimidinase-like 2
Dvl1GeneProduct13542 (Entrez Gene) full name: dishevelled, dsh homolog 1 (Drosophila)
E130012A19RikGeneProduct103551 (Entrez Gene) full name: RIKEN cDNA E130012A19 gene
EedGeneProduct13626 (Entrez Gene) full name: embryonic ectoderm development
Ehmt1GeneProduct77683 (Entrez Gene) full name: euchromatic histone methyltransferase 1
Ehmt2GeneProduct110147 (Entrez Gene) full name: euchromatic histone lysine N-methyltransferase 2
Ep300GeneProduct328572 (Entrez Gene) full name: E1A binding protein p300
Ep400GeneProduct75560 (Entrez Gene) full name: E1A binding protein p400
ErasGeneProduct353283 (Entrez Gene) full name: ES cell-expressed Ras
Ercc5GeneProduct22592 (Entrez Gene) full name: excision repair cross-complementing rodent repair deficiency, complementation group 5
EsrrbGeneProduct26380 (Entrez Gene) full name: estrogen related receptor, beta
Etv5GeneProduct104156 (Entrez Gene) full name: ets variant gene 5
Ewsr1GeneProduct14030 (Entrez Gene) full name: Ewing sarcoma breakpoint region 1
Ezh1GeneProduct14055 (Entrez Gene) full name: enhancer of zeste homolog 1 (Drosophila)
Ezh2GeneProduct14056 (Entrez Gene) full name: enhancer of zeste homolog 2 (Drosophila)
Fam129aGeneProduct63913 (Entrez Gene) full name: family with sequence similarity 129, member A
Fbxo15GeneProduct50764 (Entrez Gene) full name: F-box protein 15
Fgf4GeneProduct14175 (Entrez Gene) full name: fibroblast growth factor 4
Fgf5GeneProduct14176 (Entrez Gene) full name: fibroblast growth factor 5
Fgfr1GeneProduct14182 (Entrez Gene) full name: fibroblast growth factor receptor 1
FosGeneProduct14281 (Entrez Gene) full name: FBJ osteosarcoma oncogene
Foxd3GeneProduct15221 (Entrez Gene) full name: forkhead box D3
Frap1GeneProduct56717 (Entrez Gene) full name: FK506 binding protein 12-rapamycin associated protein 1
Fzd1GeneProduct14362 (Entrez Gene) full name: frizzled homolog 1 (Drosophila)
Gab1GeneProduct14388 (Entrez Gene) full name: growth factor receptor bound protein 2-associated protein 1
Gadd45aGeneProduct13197 (Entrez Gene) full name: growth arrest and DNA-damage-inducible 45 alpha
Gadd45gip1GeneProduct102060 (Entrez Gene) full name: growth arrest and DNA-damage-inducible, gamma interacting protein 1
Gata6GeneProduct14465 (Entrez Gene) full name: GATA binding protein 6
Gatad2aGeneProduct234366 (Entrez Gene) full name: GATA zinc finger domain containing 2A
Gatad2bGeneProduct229542 (Entrez Gene) full name: GATA zinc finger domain containing 2B
Gbx2GeneProduct14472 (Entrez Gene) full name: gastrulation brain homeobox 2
Gdf9GeneProduct14566 (Entrez Gene) full name: growth differentiation factor 9
Grb2GeneProduct14784 (Entrez Gene) full name: growthfactorreceptor-boundprotein2
Grsf1GeneProduct231413 (Entrez Gene) full name: G-rich RNA sequence binding factor 1
Gsk3bGeneProduct56637 (Entrez Gene) full name: glycogen synthase kinase 3 beta
H3f3aGeneProduct15078 (Entrez Gene) full name: H3 histone, family 3A
Hand2GeneProduct15111 (Entrez Gene) full name: heart and neural crest derivatives expressed transcript 2
Hcfc1GeneProduct15161 (Entrez Gene) full name: host cell factor C1
HckGeneProduct15162 (Entrez Gene) full name: hemopoietic cell kinase
Hdac1GeneProduct433759 (Entrez Gene) full name: histone deacetylase 1
Hdac2GeneProduct15182 (Entrez Gene) full name: Histone deacetylase 2
Hdac4GeneProduct208727 (Entrez Gene) full name: histone deacetylase 4
HellsGeneProduct15201 (Entrez Gene) full name: helicase, lymphoid specific
Hif1aGeneProduct15251 (Entrez Gene) full name: hypoxia inducible factor 1, alpha subunit
HiraGeneProduct15260 (Entrez Gene) full name: histone cell cycle regulation defective homolog A (S. cerevisiae)
HnrnpuGeneProduct51810 (Entrez Gene) full name: heterogeneous nuclear ribonucleoprotein U
Hras1GeneProduct15461 (Entrez Gene) full name: Harvey rat sarcoma virus oncogene 1
Icam1GeneProduct15894 (Entrez Gene) full name: intercellular adhesion molecule 1
Id1GeneProduct15901 (Entrez Gene) full name: inhibitor of DNA binding 1
Igfbp3GeneProduct16009 (Entrez Gene) full name: insulin-like growth factor binding protein 3
Il6stGeneProduct16195 (Entrez Gene) full name: interleukin 6 signal transducer
InhbbGeneProduct16324 (Entrez Gene) full name: inhibin beta-B
Ins1GeneProduct16333 (Entrez Gene) full name: insulin I
InsrGeneProduct16337 (Entrez Gene) full name: insulin receptor
Ipo7GeneProduct233726 (Entrez Gene) full name: importin 7
Ipo9GeneProduct226432 (Entrez Gene) full name: importin 9
Irs1GeneProduct16367 (Entrez Gene) full name: insulin receptor substrate 1
Itgb1GeneProduct16412 (Entrez Gene) full name: integrin beta 1 (fibronectin receptor beta)
Jak1GeneProduct16451 (Entrez Gene) full name: Janus kinase 1
Jarid2GeneProduct16468 (Entrez Gene) full name: jumonji, AT rich interactive domain 2
Kat5GeneProduct81601 (Entrez Gene) full name: K(lysine) acetyltransferase 5
Kdm1aGeneProduct99982 (Entrez Gene) full name: lysine (K)-specific demethylase 1A
Kdm3aGeneProduct104263 (Entrez Gene) full name: lysine (K)-specific demethylase 3A
Kdm4cGeneProduct76804 (Entrez Gene) full name: lysine (K)-specific demethylase 4C
Kdm5cGeneProduct20591 (Entrez Gene) full name: lysine (K)-specific demethylase 5C
Kdm6aGeneProduct22289 (Entrez Gene) full name: 4lysine (K)-specific demethylase 6A
Kdm6bGeneProduct216850 (Entrez Gene) full name: KDM1 lysine (K)-specific demethylase 6B
Klf2GeneProduct16598 (Entrez Gene) full name: Kruppel-like factor 2 (lung)
Klf4GeneProduct16600 (Entrez Gene) full name: Kruppel-like factor 4 (gut)
Klf5GeneProduct12224 (Entrez Gene) full name: Kruppel-like factor 5
Kpna2GeneProduct16647 (Entrez Gene) full name: karyopherin (importin) alpha 2
Kpnb1GeneProduct16211 (Entrez Gene) full name: karyopherin (importin) beta 1
Lef1GeneProduct16842 (Entrez Gene) full name: lymphoid enhancer binding factor 1
Lefty1GeneProduct13590 (Entrez Gene) full name: left right determination factor 1
Leo1GeneProduct235497 (Entrez Gene) full name: Leo1
LifGeneProduct16878 (Entrez Gene) full name: leukemia inhibitory factor
LifrGeneProduct16880 (Entrez Gene) full name: leukemia inhibitory factor receptor
Lrp5GeneProduct16973 (Entrez Gene) full name: low density lipoprotein receptor-related protein 5
LyarGeneProduct17089 (Entrez Gene) full name: Ly1 antibody reactive clone
Map2k1GeneProduct26395 (Entrez Gene) full name: mitogen-activated protein kinase kinase 1
Mapk1GeneProduct26413 (Entrez Gene) full name: mitogen-activated protein kinase 1
Mapk3GeneProduct26417 (Entrez Gene) full name: mitogen-activated protein kinase 3
Mbd2GeneProduct17191 (Entrez Gene) full name: methyl-CpG binding domain protein 2
Mbd3GeneProduct17192 (Entrez Gene) full name: methyl-CpG binding domain protein 3
Mdm2GeneProduct17246 (Entrez Gene) full name: transformed mouse 3T3 cell double minute 2
Med12GeneProduct59024 (Entrez Gene) full name: mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
Mef2cGeneProduct17260 (Entrez Gene) full name: myocyte enhancer factor 2C
Mef2dGeneProduct17261 (Entrez Gene) full name: myocyte enhancer factor 2D
MitfGeneProduct17342 (Entrez Gene) full name: microphthalmia-associated transcription factor
Mll2GeneProduct381022 (Entrez Gene) full name: myeloid/lymphoid or mixed-lineage leukemia 2, ALR
MplGeneProduct17480 (Entrez Gene) full name: myeloproliferative leukemia virus oncogene
Mta1GeneProduct116870 (Entrez Gene) full name: metastasis associated 1
Mta2GeneProduct23942 (Entrez Gene) full name: metastasis-associated gene family, member 2
Mtf2GeneProduct17765 (Entrez Gene) full name: metal response element binding transcription factor 2 / PCL2
Mybl2GeneProduct17865 (Entrez Gene) full name: myeloblastosis oncogene-like 2
MycGeneProduct17869 (Entrez Gene) full name: myelocytomatosis oncogene
MycnGeneProduct18109 (Entrez Gene) full name: v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Myod1GeneProduct17927 (Entrez Gene) full name: myogenic differentiation 1
Nacc1GeneProduct66830 (Entrez Gene) full name: nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NanogGeneProduct71950 (Entrez Gene) full name: Nanog homeobox
NclGeneProduct17975 (Entrez Gene) full name: nucleolin
Ncoa1GeneProduct17977 (Entrez Gene) full name: nuclear receptor coactivator 1
Nedd4lGeneProduct83814 (Entrez Gene) full name: neural precursor cell expressed, developmentally down-regulated gene 4-like
Nfkb1GeneProduct18033 (Entrez Gene) full name: nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
Nkd1GeneProduct93960 (Entrez Gene) full name: naked cuticle 1 homolog (Drosophila)
Nme2GeneProduct18103 (Entrez Gene) full name: non-metastatic cells 2, protein (NM23B) expressed in
NoboxGeneProduct18291 (Entrez Gene) full name: NOBOX oogenesis homeobox
NodalGeneProduct18119 (Entrez Gene) full name: Nodal homolog
Notch1GeneProduct18128 (Entrez Gene) full name: Notch gene homolog 1 (Drosophila)
NppbGeneProduct18158 (Entrez Gene) full name: natriuretic peptide precursor type B
Npr1GeneProduct18160 (Entrez Gene) full name: natriuretic peptide receptor 1
Nr0b1GeneProduct11614 (Entrez Gene) full name: nuclear receptor subfamily 0, group B, member 1
Nr2c1GeneProduct22025 (Entrez Gene) full name: nuclear receptor subfamily 2, group C, member 1
Nr2f1GeneProduct13865 (Entrez Gene) full name: nuclear receptor subfamily 2, group F, member 1
Nr2f2GeneProduct11819 (Entrez Gene) full name: nuclear receptor subfamily 2, group F, member 2
Nr2f6GeneProduct13864 (Entrez Gene) full name: nuclear receptor subfamily 2, group F, member 6
Nr5a2GeneProduct26424 (Entrez Gene) full name: nuclear receptor subfamily 5, group A, member 2
Nr6a1GeneProduct328572 (Entrez Gene) full name: nuclear receptor subfamily 6, group A, member 1
OclnGeneProduct18260 (Entrez Gene) full name: occludin
OgtGeneProduct108155 (Entrez Gene) full name: O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Otx2GeneProduct18424 (Entrez Gene) full name: orthodenticle homolog 2 (Drosophila)
P4ha1GeneProduct18451 (Entrez Gene) full name: procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
Paf1GeneProduct54624 (Entrez Gene) full name: Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
Parp1GeneProduct11545 (Entrez Gene) full name: poly (ADP-ribose) polymerase family, member 1
Pax6GeneProduct77766 (Entrez Gene) full name: paired box gene 6
Pbrm1GeneProduct66923 (Entrez Gene) full name: polybromo 1 / BAF180
PerpGeneProduct64058 (Entrez Gene) full name: PERP, TP53 apoptosis effector
Phc1GeneProduct13619 (Entrez Gene) full name: polyhomeotic-like 1 (Drosophila)
Phf17GeneProduct269424 (Entrez Gene) full name: PHD finger protein 17
Pias2GeneProduct17344 (Entrez Gene) full name: protein inhibitor of activated STAT 2
Pias4GeneProduct59004 (Entrez Gene) full name: protein inhibitor of activated STAT 4; PIASy
Pik3cdGeneProduct18707 (Entrez Gene) full name: phosphatidylinositol 3-kinase, catalytic delta polypeptide
Pim1GeneProduct18712 (Entrez Gene) full name: proviral integration site 1
Pim3GeneProduct223775 (Entrez Gene) full name: proviral integration site 3
Pin1GeneProduct23988 (Entrez Gene) full name: protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
PmlGeneProduct18854 (Entrez Gene) full name: promyelocytic leukemia
Pou2f1GeneProduct18986 (Entrez Gene) full name: POU domain, class 2, transcription factor 1
Pou5f1GeneProduct18999 (Entrez Gene) full name: POU domain, class 5, transcription factor 1
Ppp2r1aGeneProduct51792 (Entrez Gene) full name: protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
PrkacaGeneProduct18747 (Entrez Gene) full name: protein kinase, cAMP dependent, catalytic, alpha
PrkccGeneProduct18752 (Entrez Gene) full name: protein kinase C, gamma
Psen1GeneProduct19164 (Entrez Gene) full name: Presenilin 1
PtenGeneProduct19211 (Entrez Gene) full name: phosphatase and tensin homolog
Ptpn11GeneProduct19247 (Entrez Gene) full name: protein tyrosine phosphatase, non-receptor type 11
PtprsGeneProduct19280 (Entrez Gene) full name: protein tyrosine phosphatase, receptor type, S
Raf1GeneProduct110157 (Entrez Gene) full name: v-raf-leukemia viral oncogene 1
Rbbp4GeneProduct19646 (Entrez Gene) full name: retinoblastoma binding protein 4
Rbbp7GeneProduct245688 (Entrez Gene) full name: retinoblastoma binding protein 7
Rbl2GeneProduct19651 (Entrez Gene) full name: retinoblastoma-like 2
RbpjGeneProduct19664 (Entrez Gene) full name: recombination signal binding protein for immunoglobulin kappa J region
Rcn2GeneProduct26611 (Entrez Gene) full name: reticulocalbin 2
Rcor2GeneProduct104383 (Entrez Gene) full name: REST corepressor 2
RelGeneProduct19696 (Entrez Gene) full name: reticuloendotheliosis oncogene
RelaGeneProduct19697 (Entrez Gene) full name: v-rel reticuloendotheliosis viral oncogene homolog A (avian)
RelbGeneProduct19698 (Entrez Gene) full name: avian reticuloendotheliosis viral (v-rel) oncogene related B
RestGeneProduct19712 (Entrez Gene) full name: RE1-silencing transcription factor
Rif1GeneProduct51869 (Entrez Gene) full name: Rap1 interacting factor 1 homolog (yeast)
Rnf2GeneProduct19821 (Entrez Gene) full name: ring finger protein 2
Rock1GeneProduct19877 (Entrez Gene) full name: Rho-associated coiled-coil containing protein kinase 1
Rock2GeneProduct19878 (Entrez Gene) full name: Rho-associated coiled-coil containing protein kinase 2
RrasGeneProduct20130 (Entrez Gene) full name: Harvey rat sarcoma oncogene, subgroup R
Rtn4rGeneProduct65079 (Entrez Gene) full name: reticulon 4 receptor
RybpGeneProduct56353 (Entrez Gene) full name: RING1 and YY1 binding protein
Sall1GeneProduct58198 (Entrez Gene) full name: sal-like 1 (Drosophila)
Sall3GeneProduct20689 (Entrez Gene) full name: sal-like 3 (Drosophila)
Sall4GeneProduct99377 (Entrez Gene) full name: sal-like 4 (Drosophila)
Satb1GeneProduct20230 (Entrez Gene) full name: special AT-rich sequence binding protein 1
Satb2GeneProduct212712 (Entrez Gene) full name: special AT-rich sequence binding protein 2
Setdb1GeneProduct76893 (Entrez Gene) full name: SET domain, bifurcated 1
Sf1GeneProduct22668 (Entrez Gene) full name: splicing factor 1
Sgk1GeneProduct20393 (Entrez Gene) full name: serum/glucocorticoid regulated kinase 1
ShhGeneProduct20423 (Entrez Gene) full name: sonic hedgehog
Sin3aGeneProduct20466 (Entrez Gene) full name: transcriptional regulator, SIN3A (yeast)
Smad1GeneProduct17125 (Entrez Gene) full name: MAD homolog 1 (Drosophila)
Smad2GeneProduct17126 (Entrez Gene) full name: MAD homolog 2 (Drosophila)
Smad3GeneProduct17127 (Entrez Gene) full name: MAD homolog 3 (Drosophila)
Smad4GeneProduct17128 (Entrez Gene) full name: MAD homolog 4 (Drosophila)
Smad7GeneProduct17131 (Entrez Gene) full name: MADhomolog7
Smarca2GeneProduct67155 (Entrez Gene) full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Smarca4GeneProduct20586 (Entrez Gene) full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Smarca5GeneProduct93762 (Entrez Gene) full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Smarcad1GeneProduct13990 (Entrez Gene) full name: SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
Smarcc1GeneProduct20588 (Entrez Gene) full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SmoGeneProduct319757 (Entrez Gene) full name: smoothened homolog (Drosophila)
Smurf1GeneProduct75788 (Entrez Gene) full name: SMAD specific E3 ubiquitin protein ligase 1
Socs1GeneProduct216233 (Entrez Gene) full name: suppressorofcytokinesignaling2
Sos1GeneProduct20662 (Entrez Gene) full name: Son of sevenless homolog 1 (Drosophila)
Sox2GeneProduct20674 (Entrez Gene) full name: SRY-box containing gene 2
Sp1GeneProduct20683 (Entrez Gene) full name: trans-acting transcription factor 1
Sp3GeneProduct20687 (Entrez Gene) full name: trans-acting transcription factor 3
Spp1GeneProduct20750 (Entrez Gene) full name: secreted phosphoprotein 1
Ssrp1GeneProduct20833 (Entrez Gene) full name: structure specific recognition protein 1
Stat3GeneProduct20848 (Entrez Gene) full name: signal transducer and activator of transcription 3
Stk40GeneProduct74178 (Entrez Gene) full name: serine/threonine kinase 40
Sumo1GeneProduct22218 (Entrez Gene) full name: SMT3 suppressor of mif two 3 homolog 1 (yeast)
Suz12GeneProduct52615 (Entrez Gene) full name: suppressor of zeste 12 homolog (Drosophila)
TGeneProduct20997 (Entrez Gene) full name: brachyury
Tbx3GeneProduct21386 (Entrez Gene) full name: T-box3
Tcf3GeneProduct21415 (Entrez Gene) full name: transcription factor 3
Tcf7GeneProduct21414 (Entrez Gene) full name: Transcription factor7 ,T-cell specific
Tcfap2aGeneProduct21418 (Entrez Gene) full name: transcription factor AP-2, alpha
Tcfap2cGeneProduct21420 (Entrez Gene) full name: transcription factor AP-2, gamma
Tcfcp2l1GeneProduct81879 (Entrez Gene) full name: transcription factor CP2-like 1
Tcfe3GeneProduct209446 (Entrez Gene) full name: transcription factor E3
TcfebGeneProduct21425 (Entrez Gene) full name: transcription factor EB
Tcl1GeneProduct21432 (Entrez Gene) full name: T-cell lymphoma breakpoint 1
Terf2GeneProduct21750 (Entrez Gene) full name: telomeric repeat binding factor 2
TertGeneProduct21752 (Entrez Gene) full name: telomerase reverse transcriptase
Tet1GeneProduct52463 (Entrez Gene) full name: tet oncogene 1
Tgfb1GeneProduct21803 (Entrez Gene) full name: transforming growth factor, beta 1
Tgfbr1GeneProduct21812 (Entrez Gene) full name: transforming growth factor, beta receptor I / ALK5
Thap11GeneProduct59016 (Entrez Gene) full name: THAP domain containing 11
Tle2GeneProduct21886 (Entrez Gene) full name: transducin-like enhancer of split 2, homolog of Drosophila E(spl)
Tle4GeneProduct21888 (Entrez Gene) full name: Transducin-likeenhancerofsplit4
TpoGeneProduct22018 (Entrez Gene) full name: thyroid peroxidase
Trim24GeneProduct21848 (Entrez Gene) full name: tripartite motif-containing 24
Trim28GeneProduct21849 (Entrez Gene) full name: Tripartitemotif-containing28
Trim33GeneProduct94093 (Entrez Gene) full name: tripartite motif-containing 33
Trp53GeneProduct22059 (Entrez Gene) full name: transformation related protein 53
TsixGeneProduct22097 (Entrez Gene) full name: X (inactive)-specific transcript, antisense
Twist1GeneProduct22160 (Entrez Gene) full name: twist gene homolog 1 (Drosophila)
Ube2iGeneProduct22196 (Entrez Gene) full name: ubiquitin-conjugating enzyme E2I
Uhrf1GeneProduct18140 (Entrez Gene) full name: ubiquitin-like, containing PHD and RING finger domains, 1
Usp7GeneProduct252870 (Entrez Gene) full name: ubiquitin specific peptidase 7
Utf1GeneProduct22286 (Entrez Gene) full name: undifferentiated embryonic cell transcription factor 1
Wdr61GeneProduct66317 (Entrez Gene) full name: WD repeat domain 61
Wnt3aGeneProduct22416 (Entrez Gene) full name: wingless-related MMTV integration site 3A
Wnt5aGeneProduct22418 (Entrez Gene) full name: wingless-related MMTV integration site 5A
Wwp2GeneProduct66894 (Entrez Gene) full name: WW domain containing E3 ubiquitin protein ligase 2
XistGeneProduct213742 (Entrez Gene) full name: inactive X specific transcripts
XiteGeneProduct619209 (Entrez Gene) full name: X-inactivation intergenic transcription element
Xpo4GeneProduct57258 (Entrez Gene) full name: exportin 4
Yy1GeneProduct22632 (Entrez Gene) full name: YY1 transcription factor
Zfp143GeneProduct20841 (Entrez Gene) full name: zinc finger protein 143
Zfp219GeneProduct69890 (Entrez Gene) full name: zinc finger protein 219
Zfp281GeneProduct226442 (Entrez Gene) full name: zinc finger protein 281
Zfp42GeneProduct22702 (Entrez Gene) full name: zinc finger protein 42
Zfp57GeneProduct22715 (Entrez Gene) full name: zinc finger protein 57
ZfxGeneProduct22764 (Entrez Gene) full name: zinc finger protein X-linked
Zic2GeneProduct22772 (Entrez Gene) full name: zinc finger protein of the cerebellum 2
Zic3GeneProduct22773 (Entrez Gene) full name: zinc finger protein of the cerebellum 3
Zmym2GeneProduct76007 (Entrez Gene) full name: zinc finger, MYM-type 2
Zscan10GeneProduct332221 (Entrez Gene) full name: zinc finger and SCAN domain containing 10

Annotated Interactions

No annotated interactions

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