Folate Metabolism (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Methylation reactionsGroup objectNovo purine biosynthetic pathwayGroup objectOverarching processCofactorsReactionLEGENDTranscription factorSelenium statusOther proteinsCofactor conversionMetabolitesNecessary stimulationCatalysisProtein*Lipoprotein melabolismBiomarker forProtein with polymorphismNegative EffectGlycogenesisMicronutrientsSelenoproteinsis composed ofStimulationLipid peroxidationBindingProstaglandins metabolismProtein tyrosine nitrationEnzymesFrom intracellular part to the plasmaConversionProcess or metabolism involved in Se PathwayCleavageInhibitionIntracellularDNA oxidationApoptosisPlasmaMCP1Thromboxane A2Thromboxane B2SLC19A1Thromboxane B2PGF2aFOLR28-Isoprostaglandin F2aPGE1FOLR3F2-IsoprostaneMCP1PGF2aSLC46A1FOLR4FOLR1PGE2PGE1PGE2p53F2-Isoprostane8-Isoprostaglandin F2aNFkB2NFkB1RELAGroup objectMTHFD2MSR*AHCYSHMTDHFRMATMTHFD1*MTR*CBSNADP+NADP+NADP+NADP+NADP+NADP+NADP+MPOMPOCatalaseNOSCysteineCysteineFactor VIItPAPLGPAI-1ThrombintPAFactor VIIThrombinPLGPAI-1GPX 4GPX 3GPX 6GPX 2GPX 1H2O210-Formyl-THF5,10-Methenyl-THF5-Formyl-THFFGAR(11R)-hydroxymethylene-THF(11S)-hydroxymethylene-THFDihydrofolateGAR5,10-Methylene-THF5-methyl-THFFolate5-methyl-THFFolateSOD3SOD3SOD1SOD2Group objectRFKH2OGPX 3CTHHemeTHFNADPHNADPHNADPHNADPHNADPHNADPHNADPHManganeseManganeseFolic acidFolic acidRNSMTHFR*GARTMTHFSSHMTHomocysteineHomocysteinePyridoxal 5'-phosphatePyridoxal 5'-phosphateL-ArginineSerineGlycineGlycineSAA4HDL/SAAHDLSAA1VLDL/APOBAPOA1VLDLSAA3FMNHDL-CLDLAPOA1-NO2TyrSAA2SRB1LDLRoxLDLACTCholesterolTAGVLDL-TAGABCA1HDL/APOA1APOBVLDL-TAGTAGVLDLAPOBoxLDLLDLACTHDLCholesterolHDL-CAPOA1O2FAD8-OHdGCob(I)alaminFADCob(II)alaminCob(I)alamin8-OHdGADPADPChlorineMagnesiumMagnesiumChlorineCystathionineS-nitrosohomocysteineSerineATPZincZincNO2O3HNO2NONOHOClFibrinogenCSF1IL10IL6IL2CRPIFNgINSIL10IL1BHbA1cALBALBINSRHBBCSF1HbA1csICAM-1IL6IL4HBA1IL2TNFaINSIL1BIFNgFibrinD-dimerTNFaIL4D-dimerFibrinFibrinogenRiboflavinO2MethionineS-AdenosylmethionineS-AdenosylhomocysteineMethionineS-AdenosylhomocysteineS-AdenosylmethionineADPNitrotyrosineTetrahydrobiopterinONOO/ONOOHNitrotyrosineATPATPFructosamineGlucoseGlucoseFructosamineIronIronFLAD1Name: Folate MetabolismLicense: CC BY 2.0Organism: Homo sapiens