Folate Metabolism (Homo sapiens)

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22, 27026, 29419, 116, 161, 197, 204...10, 25, 116, 249, 28324921233167, 29852, 278330181, 27312488145, 186, 266Necessary stimulationMetabolitesReactionOther proteinsLEGENDNegative EffectOverarching processInhibitionProstaglandins metabolismMicronutrientsProtein*StimulationFrom intracellular part to the plasmaCleavageProtein with polymorphismCatalysisBindingProcess or metabolism involved in Se PathwayBiomarker forCofactorsLipoprotein melabolismEnzymesLipid peroxidationGlycogenesisis composed ofTranscription factorCofactor conversionSelenoproteinsConversionProtein tyrosine nitrationSelenium statusIntracellularMethylation reactionsApoptosisDNA oxidationNovo purine biosynthetic pathwayPlasmap53RELAFOLR2Thromboxane B2NFkB2PGF2aFOLR3PGF2aPGE18-Isoprostaglandin F2aMCP1NFkB1PGE28-Isoprostaglandin F2aSLC19A1MCP1Thromboxane A2PGE2FOLR1PGE1FOLR4F2-IsoprostaneF2-IsoprostaneSLC46A1Thromboxane B232832832811210, 88, 95, 186, 257...919141, 90, 2923284, 6429211, 904511290, 1419129290, 1414511, 909164AHCYMSR*SHMTMTHFD2MTHFD1*DHFRMTR*MAT3, 144, 268, 3271, 275, 286123, 1445727388254, 273133, 273CBS3, 143NADP+NADP+NADP+NADP+NADP+NADP+NADP+MPOMPOCatalaseNOS25, 114, 160, 20025, 114, 160, 2004249, 297CysteineCysteinePAI-1PAI-1PLGThrombinFactor VIItPAPLGThrombintPAFactor VII4646183, 309183, 30946227, 309464646227, 309GPX 4H2O2(11R)-hydroxymethylene-THF5-Formyl-THF5,10-Methylene-THFDihydrofolateFGAR10-Formyl-THFGAR5,10-Methenyl-THF(11S)-hydroxymethylene-THF273273181, 273273, 286273273273286181, 273Folate5-methyl-THF5-methyl-THFFolate6, 22, 28, 45, 88...286286, 327SOD3SOD3RFK255H2OGPX 3GPX 3CTH3Heme143, 249, 297THF286NADPHNADPHNADPHNADPHNADPHNADPHNADPHGPX 6ManganeseManganeseFolic acidFolic acid86, 268, 28686, 268, 286GPX 2GPX 1RNS21, 249SHMTMTHFR*MTHFSGART273273268, 286181, 273HomocysteineHomocysteine22719, 45, 99, 116, 227...SOD1Pyridoxal 5'-phosphatePyridoxal 5'-phosphate168, 3134, 168, 313SerineGlycineL-ArginineGlycine133, 273133, 273272133, 273VLDL-TAGSAA1HDL-CHDL/SAAHDL-CSAA3VLDL/APOBCholesterolAPOBHDL/APOA1HDLoxLDLSRB1ABCA1LDLRACTAPOA1SAA4TAGVLDL-TAGAPOA1FMNVLDLCholesterolAPOA1-NO2TyrAPOBACTLDLSAA2TAGLDLHDLoxLDLVLDL1652782782784418, 447, 28, 52, 200, 3072782789720, 2787, 52, 200, 3077, 28, 52, 200, 307442028, 27820, 242, 27897, 1154444242, 27828, 278242, 27817327827844242, 27897, 11518, 44447, 52, 200, 307242, 27844O22988-OHdGFADCob(I)alaminCob(II)alaminFAD8-OHdGCob(I)alamin123, 144, 241165124144124123, 144, 241123, 144ADPADPMagnesiumChlorineChlorineMagnesiumS-nitrosohomocysteineCystathionine99SOD2Serine133, 273ATPZincZincNO2HOClO3NONOHNO2114, 16099, 114, 160, 186IL2IFNgHbA1cINSIL6IL10ALBsICAM-1IL2FibrinogenTNFaCSF1HBBFibrinD-dimerD-dimerIL1BALBFibrinogenIFNgCRPHBA1HbA1cIL1BTNFaIL4IL4IL10INSINSRFibrinCSF1IL632821869, 116, 197, 3255995, 20421846, 1835995, 20446, 18327122, 6946, 216955918, 224, 2332601614, 6, 7, 154, 167...32846, 2169526018, 224, 233197, 325116, 154, 224, 310116, 271154, 16131022, 6919, 154, 203224, 32659Riboflavin38O2 S-Adenosylhomocysteine S-AdenosylmethionineMethionine S-AdenosylhomocysteineMethionine S-Adenosylmethionine144, 184, 28680, 28680, 286279, 286, 32727988, 144, 184, 286ADPTetrahydrobiopterinONOO/ONOOHNitrotyrosineNitrotyrosine2722121ATPATPGlucoseFructosamineFructosamineGlucose26059, 23359, 233260IronIron4242FLAD1126, 255