Lipoic acid metabolism (Mycobacterium tuberculosis)

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1Glycene cleavage system (H protein)Oxo-acid dehydrogenaase complexes (E2 subunit)Protein N6-(octanoyl)lysineOctanoyl-[acp]Protein N6-(lipoyl)lysinelipAFatty acid biosynthesisLipoyl-[acp]lipB


Description

Source: KEGG Pathways.

The lipoic acid metabolism is a subcategory of the "Metabolism of cofactors and vitamins".

The salvage pathway is not understood for Mycobacterium tuberculosis, and therefore only the biosynthesis is described here.

Quality Tags

Ontology Terms

 

Bibliography

  1. Zhao X, Miller JR, Jiang Y, Marletta MA, Cronan JE; ''Assembly of the covalent linkage between lipoic acid and its cognate enzymes.''; Chem Biol, 2003 PubMed

History

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CompareRevisionActionTimeUserComment
95552view13:32, 27 December 2017DeSlRemoved licence number
95477view23:54, 17 December 2017Andrachecked connectivity of lines
95433view16:40, 14 December 2017DeSlOntology Term : 'fatty acid biosynthetic pathway' added !
95432view16:40, 14 December 2017DeSlOntology Term : 'fatty acid metabolic pathway' added !
95431view16:39, 14 December 2017DeSlAdded literature reference (general for PW).
95430view16:37, 14 December 2017DeSlModified description
95429view16:35, 14 December 2017DeSlRemoved KEGG ortholog IDs, added Enzyme nomenclature IDs where needed; changed layout; converted arrows to MIM conversion, connected all enzymes where needed.
71605view19:31, 17 October 2013MaintBotAutomated update of data sources
70858view11:52, 12 September 2013AndraPeriodical save, work in progress
70856view11:31, 12 September 2013AndraConnecting lines
69520view20:13, 8 July 2013MaintBotUpdated to 2013 gpml schema
67435view11:01, 26 June 2013DdiglesOntology Term : 'lipoic acid metabolic pathway' added !
41455view01:08, 2 March 2011MaintBotRemoved redundant pathway information and comments
38987view18:51, 25 September 2010AlexanderPicoModified categories
38977view18:37, 25 September 2010AlexanderPicoModified description
38976view18:36, 25 September 2010AlexanderPico
38975view18:36, 25 September 2010AlexanderPicomodified labels and Lipoic Acid database connection
38825view10:18, 24 September 2010AllanKuchinskyadded pathway ref, labels
38824view10:14, 24 September 2010AllanKuchinskyPeriodical save, work in progress
38820view10:09, 24 September 2010AllanKuchinskySpecify description
38818view09:52, 24 September 2010AllanKuchinskyPeriodical save, work in progress
38817view09:42, 24 September 2010AllanKuchinskyPeriodical save, work in progress
38793view06:41, 24 September 2010AllanKuchinskySpecify description
38792view04:24, 24 September 2010AllanKuchinskycleaning up labels
38791view04:22, 24 September 2010AllanKuchinskyPeriodical save, work in progress
38554view17:51, 21 September 2010MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Fatty acid biosynthesisPathwayWP1647 (WikiPathways)
Lipoyl-[acp]MetaboliteC16239 (KEGG Compound)
Octanoyl-[acp]MetaboliteC05752 (KEGG Compound)
Protein N6-(lipoyl)lysineMetaboliteC16237 (KEGG Compound)
Protein N6-(octanoyl)lysineMetaboliteC16236 (KEGG Compound)
lipAGeneProductRv2218 (TubercuList) Original kegg element: gene;1;mtu:Rv2218
lipBGeneProduct2.3.1.181 (Enzyme Nomenclature) Original kegg element: gene;8;mtu:Rv2217

Annotated Interactions

No annotated interactions

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