Small Ligand GPCRs (Rattus norvegicus)

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Platelet ActivatingLysophosphatidic AcidGq/G11 PathwayCnr1Gi PathwayTbxa2rS1pr3PtgirMel-1CPtgfrMtnr1bPtger4Cnr2PTGDRProstanoidsGq/G11 PathwayPtger2S1pr1S1pr2Lpar1Ptger1S1pr4CannabinoidMtnr1aPtafrPtger3Melatonin


G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: Wikipedia These small ligand receptors are part of the Rhodopsin-like family of GPCRs. Source: Wikipedia


This pathway was inferred from Homo sapiens pathway WP247(r21199) with a 89% conversion rate.

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96074view18:43, 15 February 2018KhanspersModified description
96073view18:43, 15 February 2018KhanspersModified description
71786view20:32, 17 October 2013MaintBotAutomated update of data sources
71301view16:58, 17 October 2013MaintBotAutomated update of data sources
71008view18:57, 22 September 2013EgonwConverted pathway Label nodes into PathWay DataNodes, and three Labels into Metabolite DataNodes.
69389view18:57, 8 July 2013MaintBotUpdated to 2013 gpml schema
67649view11:44, 26 June 2013DdiglesOntology Term : 'G protein mediated signaling pathway' added !
62847view05:04, 3 May 2013MaintBotUpdated UniProt data source
41704view02:37, 2 March 2011MaintBotRemoved redundant pathway information and comments
34085view19:14, 9 December 2009MaintBotAutomatic update of empty xrefs
32352view13:38, 15 August 2009MaintBotFixed text labels
31978view13:10, 14 August 2009MaintBotFixed group labels
31401view20:49, 13 August 2009MaintBotFixed text labels
30920view00:33, 30 July 2009MaintBotConverted from Homo sapiens
21019view11:30, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Small ligand GPCRs]] moved to [[Pathway:WP161]]: Moved to stable identifier
8394view13:46, 7 January 2008MaintBot[[Pathway:Rat:Small ligand GPCRs]] moved to [[Pathway:Rattus norvegicus:Small ligand GPCRs]]: Renaming species
7814view16:19, 18 December 2007MaintBotfixed category names
7448view12:42, 4 November 2007MaintBotAdded categories to GPML
19542view22:20, 22 May 2007M.Ramirezgpml file for [[Rat:Small_ligand_GPCRs]]
6594view22:20, 22 May 2007Nsalomonisgpml file for [[Rat:Small_ligand_GPCRs]]

External references


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NameTypeDatabase referenceComment
CannabinoidMetaboliteCHEBI:67194 (ChEBI)
Cnr1GeneProduct25248 (Entrez Gene)
Cnr2GeneProduct57302 (Entrez Gene)
Gi PathwayPathway
Gq/G11 PathwayPathway
Lpar1GeneProduct116744 (Entrez Gene)
MelatoninMetaboliteCHEBI:16796 (ChEBI)
Mtnr1aGeneProduct114211 (Entrez Gene)
Mtnr1bGeneProduct192646 (Entrez Gene)
PTGDRGeneProduct498475 (Entrez Gene)
ProstanoidsMetaboliteCHEBI:26347 (ChEBI)
PtafrGeneProduct58949 (Entrez Gene)
Ptger1GeneProduct25637 (Entrez Gene)
Ptger2GeneProduct81752 (Entrez Gene)
Ptger3GeneProduct24929 (Entrez Gene)
Ptger4GeneProduct84023 (Entrez Gene)
PtgfrGeneProduct25652 (Entrez Gene)
PtgirGeneProduct292661 (Entrez Gene)
S1pr1GeneProduct29733 (Entrez Gene)
S1pr2GeneProduct29415 (Entrez Gene)
S1pr3GeneProduct306792 (Entrez Gene)
S1pr4GeneProduct314649 (Entrez Gene)
Tbxa2rGeneProduct24816 (Entrez Gene)

Annotated Interactions

No annotated interactions
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