Influenza A virus infection (Homo sapiens)

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1vRNPsPathway: Virus Assembly and ReleaseInfluenza A virus(-)Pathway: Viral Transcription and Replication(-)NucleusvRNP translocationInfluenza A virus(-)expression of late viral proteinmRNA exportH+(-)PB1NS2MIR34CN-Acetylneuraminic acidhaemagglutinin matrix protein 2GlutathioneNS1BCL2PB2neuraminidasepolymerase 1haemagglutinin nucleocapsid proteinvRNPsPB1-F2 proteinmatrix protein 1PAPANPPB2CytoplasmEndosomeInfluenza A virus


The Influenza A virus infection pathway provides an overview of the key steps in the infection including virus assembly and release and viral transcription and replication.

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Ontology Terms



  1. Ji Q, Hao X, Meng Y, Zhang M, Desano J, Fan D, Xu L; ''Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres.''; BMC Cancer, 2008 PubMed


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96032view15:41, 15 February 2018Mkutmonfix layout
96028view15:39, 15 February 2018MkutmonModified description
94906view23:40, 12 October 2017Khanspersconnected lines
94766view16:06, 5 October 2017JmeliusConnect line
80038view00:27, 2 May 2015KhanspersAdded MIR34C
78520view10:29, 7 January 2015MaintBotadded missing graphIds
73327view20:46, 20 January 2014MaintBotremoved erroneous biopax refs from gpml
73326view20:44, 20 January 2014MaintBotremoved erroneous biopax refs from gpml
67953view13:28, 28 June 2013DdiglesOntology Term : 'influenza A virus infection pathway' added !
63218view21:01, 8 May 2013MaintBotUpdating gpml version
62378view01:19, 28 April 2013AlexanderPicoCleaned up compartments and lines
45372view21:03, 7 October 2011AlexanderPicoOntology Term : 'DOID:10528' removed !
45371view21:03, 7 October 2011AlexanderPicoOntology Term : 'influenza' added !
44852view09:51, 6 October 2011MartijnVanIerselOntology Term : 'HEMOPHILUS INFLUENZA INFECTION' added !
41038view23:15, 1 March 2011MaintBotRemoved redundant pathway information and comments
33699view11:30, 4 December 2009AndraModified categories
33698view11:24, 4 December 2009AndraAdd content and reference from a paper discussing an effect to the Influenza A replication pathway
33697view11:05, 4 December 2009AndraModified description
33376view14:36, 30 November 2009MaintBotRemoved group label
33342view16:55, 24 November 2009AndraNew pathway

External references


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NameTypeDatabase referenceComment
BCL2GeneProduct596 (Entrez Gene)
GlutathioneMetaboliteHMDB00125 (HMDB)
MIR34CRnaENSG00000207562 (Ensembl)
N-Acetylneuraminic acidMetaboliteHMDB00230 (HMDB)
NS1GeneProduct956533 (Entrez Gene)
NS2GeneProduct956532 (Entrez Gene)
PAGeneProduct956535 (Entrez Gene)
PB1-F2 proteinGeneProduct3802042 (Entrez Gene)
PB2GeneProduct956536 (Entrez Gene)
haemagglutinin GeneProduct956529 (Entrez Gene)
matrix protein 1GeneProduct956527 (Entrez Gene)
matrix protein 2GeneProduct956528 (Entrez Gene)
neuraminidaseGeneProduct956530 (Entrez Gene)
nucleocapsid proteinGeneProduct956531 (Entrez Gene)
polymerase 1GeneProduct956534 (Entrez Gene)

Annotated Interactions

No annotated interactions

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