Adipogenesis (Danio rerio)

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1PreadipocyteMiscellaneousAdipocyte Secretory ProductsTranscription Factors/ModulatorsInsulin Action GenesGrowth Factors/HormonesDifferentiated adipocyteInhibitors of Preadipocyte to Adipocyte TransitionFully Differentiated Adipocyte MarkersPossible Lipodystrophy Genescebpdsocs1epas1creb1IRS3Lcyp26c1roraawnt10brb1STAT5Begr2bC10orf70adipoqlncoa1nr2f1aSTAT5Azgc:77867HMGA1RETNzmpste24DLK1GADD45AMEF2BLEPIRS2ID3PRLRnr1h3smad3bsi:ch211-134j6.3ppardbADPNGATA3ppargc1algtf3aaTWIST1srebf1hnf1azgc:109940cntfrscdbcopebfrzbPBEF1SOCS3igf1IL6rbl1gata2ancor1OSMIRS4zgc:123260mifCDKN1Aahr1bRXRGptgislpparabmbnl1wwtr1bmp1anr3c1LOC557385rxraancor2wnt5bLIFRbmp4cyp26a1gata4LOC566983fasserpine1AGPAT2LOC100006043LOC558422MIXL1STAT2bmp2bppargmef2cbLIFLOC560032LOC797300cugbp1GADD45BLOC559281GH1sp1LPLNRIP1pck1KLF7ncoa2il6stzgc:111859FZD1stat3mef2aLPIN3TGFB1hif1abLIPEmef2dlpin1RARAFOXO1AUCP1SFRP4e2f4cebpbzgc:153939insNDNagtstat1aDDIT3LOC100001938ASIPFOXC2TNFcebpaSLC2A4lmnactnnb1zgc:76966LOC565310LOC567485adfpwnt1


Description

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP236(r28133) with a 63% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Rosen ED, Spiegelman BM; ''Molecular regulation of adipogenesis.''; Annu Rev Cell Dev Biol, 2000 PubMed Europe PMC

History

View all...
CompareRevisionActionTimeUserComment
101904view16:53, 16 November 2018EgonwRemoved "undefined" as data source.
87030view14:50, 15 July 2016MkutmonOntology Term : 'signaling pathway pertinent to development' added !
85024view22:15, 5 April 2016KhanspersQuick edit to datanode annotation or property
68612view03:54, 6 July 2013MaintBotUpdated to 2013 gpml schema
40773view22:14, 1 March 2011MaintBotRemoved redundant pathway information and comments
35343view08:56, 12 February 2010MartijnVanIerseladded literature reference
35342view08:55, 12 February 2010MartijnVanIerselModified description
34165view21:16, 9 December 2009MaintBotAutomatic update of empty xrefs
31041view01:18, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADPNGeneProduct
AGPAT2GeneProduct777624 (Entrez Gene)
ASIPGeneProduct
C10orf70GeneProduct
CDKN1AGeneProduct100151416 (Entrez Gene)
DDIT3GeneProduct
DLK1GeneProduct
FOXC2GeneProduct
FOXO1AGeneProduct768121 (Entrez Gene)
FZD1GeneProduct30365 (Entrez Gene)
GADD45AGeneProduct431763 (Entrez Gene)
GADD45BGeneProduct406304 (Entrez Gene)
GATA3GeneProduct30458 (Entrez Gene)
GH1GeneProduct407639 (Entrez Gene)
HMGA1GeneProduct
ID3GeneProduct246093 (Entrez Gene)
IL6GeneProduct
IRS2GeneProduct
IRS3LGeneProduct
IRS4GeneProduct
KLF7GeneProduct553670 (Entrez Gene)
LEPGeneProduct100150233 (Entrez Gene)
LIFGeneProduct
LIFRGeneProduct
LIPEGeneProduct
LOC100001938GeneProduct100001938 (Entrez Gene)
LOC100006043GeneProduct100006043 (Entrez Gene)
LOC557385GeneProduct557385 (Entrez Gene)
LOC558422GeneProduct558422 (Entrez Gene)
LOC559281GeneProduct559281 (Entrez Gene)
LOC560032GeneProduct560032 (Entrez Gene)
LOC565310GeneProduct565310 (Entrez Gene)
LOC566983GeneProduct566983 (Entrez Gene)
LOC567485GeneProduct567485 (Entrez Gene)
LOC797300GeneProduct797300 (Entrez Gene)
LPIN3GeneProduct
LPLGeneProduct30354 (Entrez Gene)
MEF2BGeneProduct558180 (Entrez Gene)
MIXL1GeneProduct
NDNGeneProduct
NRIP1GeneProduct
OSMGeneProduct
PBEF1GeneProduct
PRLRGeneProduct
RARAGeneProduct
RETNGeneProduct
RXRGGeneProduct
SFRP4GeneProduct
SLC2A4GeneProduct
SOCS3GeneProduct
STAT2GeneProduct565200 (Entrez Gene)
STAT5AGeneProduct
STAT5BGeneProduct
TGFB1GeneProduct359834 (Entrez Gene)
TNFGeneProduct
TWIST1GeneProduct
UCP1GeneProduct
adfpGeneProduct794841 (Entrez Gene)
adipoqlGeneProduct751715 (Entrez Gene)
agtGeneProduct322485 (Entrez Gene)
ahr1bGeneProduct554265 (Entrez Gene)
bmp1aGeneProductENSDARG00000028071 (Ensembl)
bmp2bGeneProduct30632 (Entrez Gene)
bmp4GeneProduct30612 (Entrez Gene)
cebpaGeneProduct140815 (Entrez Gene)
cebpbGeneProduct140814 (Entrez Gene)
cebpdGeneProduct140817 (Entrez Gene)
cntfrGeneProduct368438 (Entrez Gene)
copebGeneProduct280650 (Entrez Gene)
creb1GeneProduct573207 (Entrez Gene)
ctnnb1GeneProduct30265 (Entrez Gene)
cugbp1GeneProduct58137 (Entrez Gene)
cyp26a1GeneProduct30381 (Entrez Gene)
cyp26c1GeneProduct554036 (Entrez Gene)
e2f4GeneProduct406741 (Entrez Gene)
egr2bGeneProduct30190 (Entrez Gene)
epas1GeneProduct555192 (Entrez Gene)
fasGeneProduct768248 (Entrez Gene)
frzbGeneProduct30119 (Entrez Gene)
gata2aGeneProduct30480 (Entrez Gene)
gata4GeneProduct30483 (Entrez Gene)
gtf3aaGeneProduct445389 (Entrez Gene)
hif1abGeneProduct393202 (Entrez Gene)
hnf1aGeneProduct266961 (Entrez Gene)
igf1GeneProduct114433 (Entrez Gene)
il6stGeneProduct100006778 (Entrez Gene)
insGeneProduct30262 (Entrez Gene)
lmnaGeneProduct195815 (Entrez Gene)
lpin1GeneProduct799099 (Entrez Gene)
mbnl1GeneProduct767696 (Entrez Gene)
mef2aGeneProduct30564 (Entrez Gene)
mef2cbGeneProduct798771 (Entrez Gene)
mef2dGeneProduct30580 (Entrez Gene)
mifGeneProduct751093 (Entrez Gene)
ncoa1GeneProduct563288 (Entrez Gene)
ncoa2GeneProduct81884 (Entrez Gene)
ncor1GeneProduct393246 (Entrez Gene)
ncor2GeneProduct561503 (Entrez Gene)
nr1h3GeneProduct548341 (Entrez Gene)
nr2f1aGeneProduct30418 (Entrez Gene)
nr3c1GeneProduct553740 (Entrez Gene)
pck1GeneProduct378727 (Entrez Gene)
pparabGeneProduct557714 (Entrez Gene)
ppardbGeneProduct30754 (Entrez Gene)
ppargGeneProduct557037 (Entrez Gene)
ppargc1alGeneProduct553418 (Entrez Gene)
ptgislGeneProduct559148 (Entrez Gene)
rb1GeneProduct777733 (Entrez Gene)
rbl1GeneProduct795522 (Entrez Gene)
roraaGeneProduct564951 (Entrez Gene)
rxraaGeneProduct555578 (Entrez Gene)
scdbGeneProduct553734 (Entrez Gene)
serpine1GeneProduct100136840 (Entrez Gene)
si:ch211-134j6.3GeneProduct563003 (Entrez Gene)
smad3bGeneProduct326283 (Entrez Gene)
socs1GeneProduct445073 (Entrez Gene)
sp1GeneProduct324109 (Entrez Gene)
srebf1GeneProduct793274 (Entrez Gene)
stat1aGeneProduct30768 (Entrez Gene)
stat3GeneProduct30767 (Entrez Gene)
wnt10bGeneProduct30308 (Entrez Gene)
wnt1GeneProduct30128 (Entrez Gene)
wnt5bGeneProduct30105 (Entrez Gene)
wwtr1GeneProduct568008 (Entrez Gene)
zgc:109940GeneProduct553553 (Entrez Gene)
zgc:111859GeneProduct335901 (Entrez Gene)
zgc:123260GeneProduct567403 (Entrez Gene)
zgc:153939GeneProduct777717 (Entrez Gene)
zgc:76966GeneProduct405805 (Entrez Gene)
zgc:77867GeneProduct406473 (Entrez Gene)
zmpste24GeneProduct334380 (Entrez Gene)

Annotated Interactions

No annotated interactions
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