Non-homologous end joining (Equus caballus)

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XP_001500404.2NHEJ1XP_001500404.2Q8WN21_HORSEXP_001504492.1Q8WN21_HORSEXP_001500404.2Nbs1 ?XP_001504687.1XP_001500404.2MRE11AXP_001489450.2XP_001500404.2XP_001504687.1Q8WN21_HORSEQ8WN21_HORSEQ8WN21_HORSEXP_001489450.2Q8WN21_HORSELigase VXP_001489450.2XP_001500404.2XP_001489450.2XP_001500404.2XP_001489450.2XLFXP_001489450.2XP_001500404.2XP_001500404.2XP_001489450.2XP_001500404.2XP_001489450.2Q8WN21_HORSEQ8WN21_HORSELigase VXP_001489450.2XP_001489450.2


Description

(From http://en.wikipedia.org/wiki/Non-homologous_end_joining) Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA. NHEJ is referred to as "non-homologous" because the break ends are directly ligated without the need for a homologous template, in contrast to homologous recombination, which requires a homologous sequence to guide repair. NHEJ is evolutionarily conserved throughout all kingdoms of life and is the predominant double-strand break repair pathway in mammalian cells.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP438(r29612) with a 86% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
87938view13:03, 25 July 2016ElisaOntology Term : 'DNA repair pathway' added !
87937view13:03, 25 July 2016ElisaOntology Term : 'regulatory pathway' added !
79378view19:52, 21 March 2015Khanspersupdating schema
79377view19:51, 21 March 2015KhanspersReverted to version '00:33, 21 February 2013' by Khanspers
68740view22:51, 6 July 2013MaintBotUpdated to 2013 gpml schema
58873view00:33, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
40913view22:41, 1 March 2011MaintBotRemoved redundant pathway information and comments
35401view09:54, 12 February 2010MartijnVanIerselModified description
31817view12:23, 14 August 2009MaintBotFixed group labels
30777view23:27, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
Ligase VGeneProduct
MRE11AGeneProductENSECAG00000000295 (Ensembl)
NHEJ1GeneProduct
Nbs1 ?GeneProduct
Q8WN21_HORSEGeneProductENSECAG00000020168 (Ensembl)
XLFGeneProduct
XP_001489450.2GeneProductENSECAG00000015940 (Ensembl)
XP_001500404.2GeneProductENSECAG00000017563 (Ensembl)
XP_001504492.1GeneProductENSECAG00000010922 (Ensembl)
XP_001504687.1GeneProductENSECAG00000020269 (Ensembl)

Annotated Interactions

No annotated interactions
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