IL-4 signaling Pathway (Canis familiaris)

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DSumoylationControlCY -> PMPlasma membraneAcetylationCY -> NUDCY -> PMProteolytic cleavageMethylationGlycosylationMitochondrionActivationCY -> PMNucleusECCY -> PM(Protein-protein interaction)DeubiquitinationAccession Number: NetPath 16DAutophosphorylationENDemethylationDRecruitmentPalmitoylationDExtracellularDephosphorylationNUUbiquitinationDMolecular associationGOERGolgi apparatusDCytoplasmPMReceptorEnzyme complexPhosphorylationEndoplasmic reticulumReaction through unknown mechanisms/moleculesCY -> NUDEndosomeMTCYTranslocationProteins in a complex interactionLigandInhibitionMolecule in the pathwayDeacetylationDesumoylationDJAK1STAT6NCF1STAT6Gene SymbolMAPK3MAPK1PTPN6STAMIL4MAPK14IL13RA1AKT1EP300FYNIL4RSOCS5BCL2L1CBLPTPN11SOCS3JAK2LCKRPS6KB1PLCG1JAK2STAT6PAWRSPI1PIK3R1PRKCZJAK3STAT6ETS1MAPK14STAT1JAK1PRKD3FESIRS1ATF2CXCR4DOK2PIK3CAHIST2H3CSOS1BADADRBK2HMGA1PRKCZINPP5DSTAT6SRCPRKCDIRS2NFKB1STAT5ASOCS1PIK3R2CREBBPIL2RGELK1TYK2PRKCIIL4RPRKD3PIK3CDRELAPTK2RASA1PRKCIPRKCDNFKB1MAPK11GRB2IL4SHC1


Description

No description

Comments

GenMAPP notes 
NetPath 16 - IL-4 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP395(r28126) with a 84% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
86929view13:04, 15 July 2016MkutmonOntology Term : 'interleukin-4 signaling pathway' added !
68538view22:23, 5 July 2013MaintBotUpdated to 2013 gpml schema
40694view21:50, 1 March 2011MaintBotRemoved redundant pathway information and comments
33978view18:31, 9 December 2009MaintBotAutomatic update of empty xrefs
31285view20:04, 13 August 2009MaintBotFixed text labels
30740view23:02, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADRBK2GeneProduct486327 (Entrez Gene)
AKT1GeneProduct490878 (Entrez Gene)
ATF2GeneProduct478806 (Entrez Gene)
BADGeneProduct483763 (Entrez Gene)
BCL2L1GeneProduct403618 (Entrez Gene)
CBLGeneProduct
CREBBPGeneProduct479866 (Entrez Gene)
CXCR4GeneProduct483900 (Entrez Gene)
DOK2GeneProduct486133 (Entrez Gene)
ELK1GeneProduct491860 (Entrez Gene)
EP300GeneProduct
ETS1GeneProduct489287 (Entrez Gene)
FESGeneProduct609483 (Entrez Gene)
FYNGeneProduct475032 (Entrez Gene)
GRB2GeneProduct483312 (Entrez Gene)
Gene SymbolGeneProduct
HIST2H3CGeneProduct
HMGA1GeneProduct442946 (Entrez Gene)
IL13RA1GeneProduct403623 (Entrez Gene)
IL2RGGeneProduct403851 (Entrez Gene)
IL4GeneProduct403785 (Entrez Gene)
IL4RGeneProduct489957 (Entrez Gene)
INPP5DGeneProduct
IRS1GeneProduct486148 (Entrez Gene)
IRS2GeneProduct485548 (Entrez Gene)
JAK1GeneProduct442952 (Entrez Gene)
JAK2GeneProduct484185 (Entrez Gene)
JAK3GeneProduct610004 (Entrez Gene)
LCKGeneProduct478151 (Entrez Gene)
MAPK11GeneProduct607019 (Entrez Gene)
MAPK14GeneProduct403856 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
NCF1GeneProduct607700 (Entrez Gene)
NFKB1GeneProduct442859 (Entrez Gene)
PAWRGeneProduct
PIK3CAGeneProduct488084 (Entrez Gene)
PIK3CDGeneProduct489644 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PIK3R2GeneProduct609956 (Entrez Gene)
PLCG1GeneProduct485874 (Entrez Gene)
PRKCDGeneProduct494005 (Entrez Gene)
PRKCIGeneProduct478686 (Entrez Gene)
PRKCZGeneProduct479577 (Entrez Gene)
PRKD3GeneProduct483036 (Entrez Gene)
PTK2GeneProduct475108 (Entrez Gene)
PTPN11GeneProduct477488 (Entrez Gene)
PTPN6GeneProduct486717 (Entrez Gene)
RASA1GeneProduct479158 (Entrez Gene)
RELAGeneProduct483729 (Entrez Gene)
RPS6KB1GeneProduct480580 (Entrez Gene)
SHC1GeneProduct490439 (Entrez Gene)
SOCS1GeneProduct490006 (Entrez Gene)
SOCS3GeneProduct442949 (Entrez Gene)
SOCS5GeneProduct474581 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene)
SPI1GeneProduct611255 (Entrez Gene)
SRCGeneProduct485864 (Entrez Gene)
STAMGeneProduct477990 (Entrez Gene)
STAT1GeneProduct488449 (Entrez Gene)
STAT5AGeneProduct490968 (Entrez Gene)
STAT6GeneProduct100142679 (Entrez Gene)
TYK2GeneProduct476714 (Entrez Gene)

Annotated Interactions

No annotated interactions
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