GPCRs, Other (Homo sapiens)

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1, 2LGR6RLN3R1OR51A1PEMR3OR7E35POR10A2OR8G2GRM8CCR5GRM1OR3A4CCKBRVN1R1OR2A9POR2B6GPR88ADORA3OR10A5GPR73L1IL8RBHTR2AOR2H1GPR133Q9UEB1GPR18HSA12OR1J5EDG1SMOOR5D3FYOR1N1OR2A4CHRM3GPR55OR7E24GPR83HTR1FUTS2RGPR17OR2M4CNR1LPHN2OR5-85PTGFROR1R1POR1E1OR7E19PP47889CXCR3OR3A3OR1F1EBI2CCR2OR1G1HSA3EMR2GPR77P2RY11TAAR5OR8G1IL8RAHSA1GPR132CELSR2ADRB2OR10A1ALG6GPR84OR2A20PHSA10DRD3HRH4LTB4R2GRCAEDNRALPHN3OR1E3PDRD4P2RY13OR2F1GPR116Q9BYT4CELSR1ADRA1DO60411OR7E18PCELSR3OR3A1FSHRGPRGRPRGPR145GPR143GPR56CHRM2TAAR3GPR61SSTR2Q9H2C7GPR135LGR7GPR62OR5E1PHTR7OR2A5HSA8ADORA2AGHRHRNTSR1F2RMASS1TAAR2GNRHROR5D3P


Description

This pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references. Proteins on this pathway have targeted assays available via the CPTAC Assay Portal

Quality Tags

Ontology Terms

 

Bibliography

  1. Karchin R, Karplus K, Haussler D; ''Classifying G-protein coupled receptors with support vector machines.''; Bioinformatics, 2002 PubMed Europe PMC
  2. Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, Edvardsen O, Campagne F, Vriend G; ''GPCRDB: an information system for G protein-coupled receptors.''; Nucleic Acids Res, 1998 PubMed Europe PMC

History

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CompareRevisionActionTimeUserComment
107421view12:49, 6 October 2019EgonwReplaced a deprecated UniProt identifiers with the current one.
106427view23:20, 28 August 2019KhanspersModified description
106381view11:53, 24 August 2019EgonwRemoved three more deleted UniProt identifiers.
106380view09:31, 24 August 2019EgonwRemoved a no longer existing protein sequence and no clear replacement.
105603view04:51, 10 August 2019KhanspersModified description
82985view00:19, 17 November 2015Mkutmonspecial character issue in literature references fixed
82862view15:26, 10 November 2015Mkutmoncorrect outdated identifiers
80021view20:30, 30 April 2015Zari
79718view08:49, 6 April 2015EgonwAdded the two references cited in the Description.
79711view08:33, 6 April 2015EgonwModified description
79657view17:46, 1 April 2015Khansperschanged non-numeric Entrez id
71231view23:38, 15 October 2013MaintBotAutomated update of data sources
63206view20:56, 8 May 2013MaintBotUpdating gpml version
62692view21:35, 1 May 2013MaintBotupdated uniprot data source
45343view20:24, 7 October 2011AlexanderPicoOntology Term : 'G protein mediated signaling pathway' added !
45105view22:26, 6 October 2011AlexanderPicofixed uniprot refs
41044view23:16, 1 March 2011MaintBotRemoved redundant pathway information and comments
38915view20:52, 24 September 2010Khanspers
34573view22:04, 21 December 2009KhanspersModified description
34545view20:00, 21 December 2009KhanspersModified description
34544view19:59, 21 December 2009KhanspersChanged xrefs
34543view19:33, 21 December 2009KhanspersModified description
20929view11:30, 14 November 2008MaintBot[[Pathway:Homo sapiens:GPCRDB Other]] moved to [[Pathway:WP117]]: Moved to stable identifier
8120view13:46, 7 January 2008MaintBot[[Pathway:Human:GPCRDB Other]] moved to [[Pathway:Homo sapiens:GPCRDB Other]]: Renaming species
7681view16:09, 18 December 2007MaintBotfixed category names
7425view12:42, 4 November 2007MaintBotAdded categories to GPML
19491view22:17, 22 May 2007BruceConklingpml file for [[Human:GPCRDB_Other]]
6324view22:17, 22 May 2007Nsalomonisgpml file for [[Human:GPCRDB_Other]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADORA2AGeneProduct135 (Entrez Gene)
ADORA3GeneProduct140 (Entrez Gene)
ADRA1DGeneProduct146 (Entrez Gene)
ADRB2GeneProduct154 (Entrez Gene)
ALG6GeneProduct29929 (Entrez Gene)
CCKBRGeneProduct887 (Entrez Gene)
CCR2GeneProduct1231 (Entrez Gene)
CCR5GeneProduct1234 (Entrez Gene)
CELSR1GeneProduct9620 (Entrez Gene)
CELSR2GeneProduct1952 (Entrez Gene)
CELSR3GeneProduct1951 (Entrez Gene)
CHRM2GeneProduct1129 (Entrez Gene)
CHRM3GeneProduct1131 (Entrez Gene)
CNR1GeneProduct1268 (Entrez Gene)
CXCR3GeneProduct2833 (Entrez Gene)
DRD3GeneProduct1814 (Entrez Gene)
DRD4GeneProduct1815 (Entrez Gene)
EBI2GeneProduct1880 (Entrez Gene)
EDG1GeneProduct1901 (Entrez Gene)
EDNRAGeneProduct1909 (Entrez Gene)
EMR2GeneProduct30817 (Entrez Gene)
EMR3GeneProduct84658 (Entrez Gene)
F2RGeneProduct2149 (Entrez Gene)
FSHRGeneProduct2492 (Entrez Gene)
FYGeneProduct2532 (Entrez Gene)
GHRHRGeneProduct2692 (Entrez Gene)
GNRHRGeneProduct2798 (Entrez Gene)
GPRGeneProduct11245 (Entrez Gene)
GPR116GeneProduct221395 (Entrez Gene)
GPR132GeneProduct29933 (Entrez Gene)
GPR133GeneProduct283383 (Entrez Gene)
GPR135GeneProduct64582 (Entrez Gene)
GPR143GeneProduct4935 (Entrez Gene)
GPR145GeneProduct84539 (Entrez Gene)
GPR17GeneProduct2840 (Entrez Gene)
GPR18GeneProduct2841 (Entrez Gene)
GPR55GeneProduct9290 (Entrez Gene)
GPR56GeneProduct9289 (Entrez Gene)
GPR61GeneProduct83873 (Entrez Gene)
GPR62GeneProduct118442 (Entrez Gene)
GPR73L1GeneProduct128674 (Entrez Gene)
GPR77GeneProduct27202 (Entrez Gene)
GPR83GeneProduct10888 (Entrez Gene)
GPR84GeneProduct53831 (Entrez Gene)
GPR88GeneProduct54112 (Entrez Gene)
GRCAGeneProduct27239 (Entrez Gene)
GRM1GeneProduct2911 (Entrez Gene)
GRM8GeneProduct2918 (Entrez Gene)
GRPRGeneProduct2925 (Entrez Gene)
HRH4GeneProduct59340 (Entrez Gene)
HSA10GeneProductQ9NZP4 (Uniprot-TrEMBL)
HSA12GeneProductQ9NZP3 (Uniprot-TrEMBL)
HSA1GeneProductQ9NZP5 (Uniprot-TrEMBL)
HSA3GeneProductQ9NZP2 (Uniprot-TrEMBL)
HSA8GeneProductQ9NZP0 (Uniprot-TrEMBL)
HTR1FGeneProduct3355 (Entrez Gene)
HTR2AGeneProduct3356 (Entrez Gene)
HTR7GeneProduct3363 (Entrez Gene)
IL8RAGeneProduct3577 (Entrez Gene)
IL8RBGeneProduct3579 (Entrez Gene)
LGR6GeneProduct59352 (Entrez Gene)
LGR7GeneProduct59350 (Entrez Gene)
LPHN2GeneProduct23266 (Entrez Gene)
LPHN3GeneProduct23284 (Entrez Gene)
LTB4R2GeneProduct56413 (Entrez Gene)
MASS1GeneProduct84059 (Entrez Gene)
NTSR1GeneProduct4923 (Entrez Gene)
O60411GeneProductO60411 (Uniprot-TrEMBL)
OR10A1GeneProduct144124 (Entrez Gene)
OR10A2GeneProduct341276 (Entrez Gene)
OR10A5GeneProduct144124 (Entrez Gene)
OR1E1GeneProduct8387 (Entrez Gene)
OR1E3PGeneProduct8389 (Entrez Gene)
OR1F1GeneProduct4992 (Entrez Gene)
OR1G1GeneProduct8390 (Entrez Gene)
OR1J5GeneProduct81370 (Entrez Gene)
OR1N1GeneProduct138883 (Entrez Gene)
OR1R1PGeneProduct9596 (Entrez Gene)
OR2A20PGeneProduct401428 (Entrez Gene)
OR2A4GeneProduct79541 (Entrez Gene)
OR2A5GeneProduct393046 (Entrez Gene)
OR2A9PGeneProductENSG00000228960 (Ensembl)
OR2B6GeneProduct26212 (Entrez Gene)
OR2F1GeneProduct26211 (Entrez Gene)
OR2H1GeneProduct26716 (Entrez Gene)
OR2M4GeneProduct26245 (Entrez Gene)
OR3A1GeneProduct4994 (Entrez Gene)
OR3A3GeneProduct8392 (Entrez Gene)
OR3A4GeneProductENSG00000180068 (Ensembl)
OR5-85GeneProductP30953 (Uniprot-TrEMBL)
OR51A1PGeneProduct26537 (Entrez Gene)
OR5D3GeneProductO95220 (Uniprot-TrEMBL)
OR5D3PGeneProduct8594 (Entrez Gene)
OR5E1PGeneProductENSG00000170688 (Ensembl)
OR7E18PGeneProduct390885 (Entrez Gene)
OR7E19PGeneProduct26651 (Entrez Gene)
OR7E24GeneProduct26648 (Entrez Gene)
OR7E35PGeneProduct391632 (Entrez Gene)
OR8G1GeneProduct26494 (Entrez Gene)
OR8G2GeneProduct26492 (Entrez Gene)
P2RY11GeneProduct5032 (Entrez Gene)
P2RY13GeneProduct53829 (Entrez Gene)
P47889GeneProductP47889 (Uniprot-TrEMBL)
PTGFRGeneProduct5737 (Entrez Gene)
Q9BYT4GeneProductQ9BYT4 (Uniprot-TrEMBL)
Q9H2C7GeneProductQ9H2C7 (Uniprot-TrEMBL)
Q9UEB1GeneProductENSG00000185385 (Ensembl)
RLN3R1GeneProduct51289 (Entrez Gene)
SMOGeneProduct6608 (Entrez Gene)
SSTR2GeneProduct6752 (Entrez Gene)
TAAR2GeneProduct9287 (Entrez Gene)
TAAR3GeneProduct9288 (Entrez Gene)
TAAR5GeneProduct9038 (Entrez Gene)
UTS2RGeneProduct2837 (Entrez Gene)
VN1R1GeneProduct57191 (Entrez Gene)

Annotated Interactions

No annotated interactions

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