IL-7 Signaling Pathway (Canis familiaris)

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DesumoylationMolecular associationEndosomeMolecule in the pathwayActivationMethylationPMUbiquitinationDeacetylationExtracellularMTCYENProteins in a complex interactionDephosphorylationInhibitionNucleusControlAutophosphorylationSumoylationGolgi apparatusNUEnzyme complexDRecruitmentLigandTranslocationMitochondrionAcetylationPalmitoylationPlasma membraneDReaction through unknown mechanisms/moleculesGlycosylationProteolytic cleavageDeubiquitinationECReceptorDDemethylation(Protein-protein interaction)Accession Number: NetPath 19GOPhosphorylationCytoplasmIRS1CBLBCBLMUC1PIK3R1IRF1IL2RGGene SymbolSTAT3BCL2L11SOS1MAPK3JAK1CDK4PIK3R1STAMIRS2STAT1BADSTAM2MCL1FYNIL7RLYNMAPK1FOXO1HRASCDK2GSK3BRB1JAK3SHC1BAXMAP2K1GRB2AKT1CLTCPTK2BSTAT5BMAP2K2CCND2RAF1BLKFOXO3ASTAT5ACCNA2


Description

No description

Comments

GenMAPP notes 
NetPath 19 – IL-7 Signaling Pathway


The annotation of immune signaling pathways (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use these pathways, you must cite these websites.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP205(r21111) with a 91% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

CompareRevisionActionTimeUserComment
86941view13:09, 15 July 2016MkutmonOntology Term : 'interleukin-7 signaling pathway' added !
68595view23:21, 5 July 2013MaintBotUpdated to 2013 gpml schema
40755view21:54, 1 March 2011MaintBotRemoved redundant pathway information and comments
30700view22:49, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct490878 (Entrez Gene)
BADGeneProduct483763 (Entrez Gene)
BAXGeneProduct403523 (Entrez Gene)
BCL2L11GeneProduct612867 (Entrez Gene)
BLKGeneProduct486080 (Entrez Gene)
CBLGeneProduct
CBLBGeneProduct487965 (Entrez Gene)
CCNA2GeneProduct483845 (Entrez Gene)
CCND2GeneProduct611782 (Entrez Gene)
CDK2GeneProduct606931 (Entrez Gene)
CDK4GeneProduct481131 (Entrez Gene)
CLTCGeneProduct480578 (Entrez Gene)
FOXO1GeneProduct477295 (Entrez Gene)
FOXO3AGeneProduct
FYNGeneProduct475032 (Entrez Gene)
GRB2GeneProduct483312 (Entrez Gene)
GSK3BGeneProduct478575 (Entrez Gene)
Gene SymbolGeneProduct
HRASGeneProduct
IL2RGGeneProduct403851 (Entrez Gene)
IL7RGeneProduct612582 (Entrez Gene)
IRF1GeneProduct481500 (Entrez Gene)
IRS1GeneProduct486148 (Entrez Gene)
IRS2GeneProduct485548 (Entrez Gene)
JAK1GeneProduct442952 (Entrez Gene)
JAK3GeneProduct610004 (Entrez Gene)
LYNGeneProduct477886 (Entrez Gene)
MAP2K1GeneProduct478347 (Entrez Gene)
MAP2K2GeneProduct611939 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
MCL1GeneProduct403537 (Entrez Gene)
MUC1GeneProduct448784 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PTK2BGeneProduct486102 (Entrez Gene)
RAF1GeneProduct484648 (Entrez Gene)
RB1GeneProduct476915 (Entrez Gene)
SHC1GeneProduct490439 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene)
STAM2GeneProduct476150 (Entrez Gene)
STAMGeneProduct477990 (Entrez Gene)
STAT1GeneProduct488449 (Entrez Gene)
STAT3GeneProduct490967 (Entrez Gene)
STAT5AGeneProduct490968 (Entrez Gene)
STAT5BGeneProduct490969 (Entrez Gene)

Annotated Interactions

No annotated interactions
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