Prostaglandin Synthesis and Regulation (Canis familiaris)

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Cell MembranePhospholipidsCytoplasmPG SynthasesInactive MetabolitesprolactinreleaseCortisoneGq signalingpathwayEDNRAPTGER4PTGS2PLA2G4AProstaglandin H2Arachidonic AcidANXA4LOC478365TXA2SCGB1A1HSD11B1CortisolANXA8CortisolPGF2aPTGER1TBXAS1ANXA6HSD11B2PTGER2PGE2CalciumPGF2aEDNRBPTGIREDN1S100A6PTGS1PRLANXA1ProgesteroneANXA2ANXA5CalciumPTGER3PTGDSPGI2S100A10ANXA3HPGDPTGDRPTGFRPTGIS


Description

No description

Comments

GenMAPP notes 
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks 
See note for more details
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP98(r20887) with a 80% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
106037view11:56, 16 August 2019MaintBotHMDB identifier normalization
87601view08:53, 25 July 2016LindarieswijkOntology Term : 'prostaglandin biosynthetic pathway' added !
87600view08:53, 25 July 2016LindarieswijkOntology Term : 'prostaglandin signaling pathway' added !
71459view19:17, 17 October 2013MaintBotAutomated update of data sources
68524view22:08, 5 July 2013MaintBotUpdated to 2013 gpml schema
40678view21:49, 1 March 2011MaintBotRemoved redundant pathway information and comments
33968view18:27, 9 December 2009MaintBotAutomatic update of empty xrefs
32549view13:05, 17 August 2009MaintBotFixed text labels
32231view12:49, 15 August 2009MaintBotFixed text labels
31737view11:59, 14 August 2009MaintBotFixed group labels
31247view19:50, 13 August 2009MaintBotFixed text labels
30680view22:43, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ANXA1GeneProduct476322 (Entrez Gene)
ANXA2GeneProduct403435 (Entrez Gene)
ANXA3GeneProduct478447 (Entrez Gene)
ANXA4GeneProduct606756 (Entrez Gene)
ANXA5GeneProduct476094 (Entrez Gene)
ANXA6GeneProduct479325 (Entrez Gene)
ANXA8GeneProduct
Arachidonic AcidMetabolite
CalciumMetaboliteHMDB0000464 (HMDB)
CortisolMetabolite
EDN1GeneProduct403424 (Entrez Gene) PMID: 1474344
EDNRAGeneProduct450187 (Entrez Gene)
EDNRBGeneProduct403862 (Entrez Gene)
HPGDGeneProduct486073 (Entrez Gene)
HSD11B1GeneProduct449023 (Entrez Gene)
HSD11B2GeneProduct489758 (Entrez Gene)
LOC478365GeneProduct478365 (Entrez Gene)
PGE2MetaboliteHMDB0003175 (HMDB)
PGF2aMetaboliteHMDB0001139 (HMDB)
PGI2MetaboliteHMDB0001335 (HMDB)
PLA2G4AGeneProduct480048 (Entrez Gene)
PRLGeneProduct488241 (Entrez Gene)
PTGDRGeneProduct610845 (Entrez Gene)
PTGDSGeneProduct403740 (Entrez Gene)
PTGER1GeneProduct610774 (Entrez Gene)
PTGER2GeneProduct403797 (Entrez Gene)
PTGER3GeneProduct403430 (Entrez Gene)
PTGER4GeneProduct403589 (Entrez Gene)
PTGFRGeneProduct479981 (Entrez Gene)
PTGIRGeneProduct484429 (Entrez Gene)
PTGISGeneProduct485919 (Entrez Gene)
PTGS1GeneProduct403544 (Entrez Gene)
PTGS2GeneProduct442942 (Entrez Gene)
ProgesteroneMetabolite
Prostaglandin H2Metabolite
S100A10GeneProduct475851 (Entrez Gene) PMID: 12962548 relationship with Annexin 2
S100A6GeneProduct480143 (Entrez Gene)
SCGB1A1GeneProduct476060 (Entrez Gene) PMID: 7615804, PMID: 3292559
TBXAS1GeneProduct482771 (Entrez Gene)
TXA2MetaboliteHMDB0001452 (HMDB)

Annotated Interactions

No annotated interactions
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