Keap1-Nrf2 (Canis familiaris)

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1T-PCCAAT/XRET-PNucleusS-PARES-PPhase II enzymesMAFGCLMCurcumin6-HITCNQO1MAPK8EPHB2NFE2L2PIK3CASulforaphaneAIMP2GSTA2KEAP1C/EBP-betaPRKCAHMOX1Caffeic acid phenethyl esterKEAP1GCLCC/EBP-betaNFE2L2NFE2L2


Description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP3(r29720) with a 77% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Surh YJ; ''Cancer chemoprevention with dietary phytochemicals.''; Nat Rev Cancer, 2003 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
106034view11:56, 16 August 2019MaintBotHMDB identifier normalization
88679view15:44, 12 August 2016JmeliusOntology Term : 'nuclear factor, erythroid derived 2, like 2 signaling pathway' added !
88678view15:44, 12 August 2016JmeliusOntology Term : 'oxidative stress response pathway' added !
74169view14:50, 2 April 2014EgonwUpdated the PubChem-compound data source.
71464view19:17, 17 October 2013MaintBotAutomated update of data sources
68534view22:19, 5 July 2013MaintBotUpdated to 2013 gpml schema
40690view21:50, 1 March 2011MaintBotRemoved redundant pathway information and comments
31731view11:57, 14 August 2009MaintBotFixed group labels
30675view22:41, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
6-HITCMetaboliteFull name: 6-(Methylsulfinyl)hexylisothiocyanate, or Japanese horseradish wasabi
AIMP2GeneProduct479752 (Entrez Gene)
C/EBP-betaGeneProduct
Caffeic acid phenethyl esterMetabolite
CurcuminMetaboliteHMDB0002269 (HMDB)
EPHB2GeneProduct487380 (Entrez Gene)
GCLCGeneProduct609822 (Entrez Gene)
GCLMGeneProduct612283 (Entrez Gene)
GSTA2GeneProduct
HMOX1GeneProduct442987 (Entrez Gene)
KEAP1GeneProduct476713 (Entrez Gene)
MAFGeneProduct
MAPK8GeneProduct477746 (Entrez Gene)
NFE2L2GeneProduct478813 (Entrez Gene)
NQO1GeneProduct610935 (Entrez Gene)
PIK3CAGeneProduct488084 (Entrez Gene)
PRKCAGeneProduct490904 (Entrez Gene)
SulforaphaneMetabolite5350 (PubChem-compound)

Annotated Interactions

No annotated interactions
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