Complement Activation, Classical Pathway (Canis familiaris)

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CytoplasmPrevents Complement AttackProteolytic CleavageMembraneattack complexPlasmaMembraneC1 complexComplexFormationantigen/antibodycomplexaggregated IgG,IgM-antigen complex,polyanions, RNA, DNAlipopolysaccharidesIonsC2C8ACD55C9MASP1C1QBC7C1RC4AC1SC5C1QCC4BC6C8BH2OC1QAC3


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP545(r21826) with a 76% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
106032view11:55, 16 August 2019MaintBotHMDB identifier normalization
89188view03:55, 23 August 2016AriuttaOntology Term : 'regulatory pathway' added !
89187view03:55, 23 August 2016AriuttaOntology Term : 'classical complement pathway' added !
68543view22:29, 5 July 2013MaintBotUpdated to 2013 gpml schema
40699view21:51, 1 March 2011MaintBotRemoved redundant pathway information and comments
33981view18:32, 9 December 2009MaintBotAutomatic update of empty xrefs
32543view13:03, 17 August 2009MaintBotFixed text labels
32226view12:48, 15 August 2009MaintBotFixed text labels
31724view11:56, 14 August 2009MaintBotFixed group labels
31241view19:48, 13 August 2009MaintBotFixed text labels
30664view22:37, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
C1QAGeneProduct478194 (Entrez Gene) update: C1QA HUMAN
C1QBGeneProduct487381 (Entrez Gene)
C1QCGeneProduct487382 (Entrez Gene) update C1QC HUMAN
C1RGeneProduct477707 (Entrez Gene)
C1SGeneProduct486714 (Entrez Gene)
C2GeneProduct
C3GeneProduct476728 (Entrez Gene)
C4AGeneProduct
C4BGeneProduct
C5GeneProduct474816 (Entrez Gene)
C6GeneProduct479348 (Entrez Gene)
C7GeneProduct489221 (Entrez Gene)
C8AGeneProduct479556 (Entrez Gene)
C8BGeneProduct479555 (Entrez Gene)
C9GeneProduct479354 (Entrez Gene)
CD55GeneProduct609307 (Entrez Gene)
H2OMetaboliteHMDB0002111 (HMDB)
MASP1GeneProduct488121 (Entrez Gene)

Annotated Interactions

No annotated interactions
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