IL-5 Signaling Pathway (Canis familiaris)

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NucleusEndosomeCY->NUDDPM->NUCytoplasmCY->MTCYDPhosphorylationDephosphorylationNUPMControlDAccession Number: NetPath 17ActivationLigandGene SymbolDDTranslocationDDemethylationDPlasma membraneMTDeacetylationGlycosylationPM->NUDProteins in a complex interactionReaction through unknown mechanisms/moleculesEndoplasmic reticulumCY->NUDDDAcetylationExtracellularCY->NUDAutophosphorylationDGolgi apparatusENPM->NUEnzyme complexSumoylationDInhibitionMolecule in the pathwayECGOERMolecular associationUbiquitinationMitochondriaDCY->PMPalmitoylationDDesumoylationDeubiquitination(Protein-protein interaction)MethylationRecruitmentReceptorDProteolytic cleavageMAPK3YWHAZBTKFOXO3AITGB2GSK3APIM1NFKB1IL5STAT5ARAC1PLA2G4ADNM2PRKCDHRASALOX5APRPS6KA1ELK1SOCS1IL5RAALOX5ICAM3RAPGEF1STAT5AUNC119PRKCBICAM1PIK3CGCDKN1BSHC2NFKBIAPIK3R1PTK2BCRKLSYKALOX5CSF2RBCTNNB1STAT3SHC1SOX4NFKB1VAV1ITGAMGSK3BCRKLPTPN6JUNMAPK9STAT5BRAP1GAPIL5HCKBAXPRKCDMAP2K2CBLAKT1STAT5BIL2RBMAPK14RAF1BAXMAPK1HRASCSF2RBIL5RAATF2SH2B2GRB2JAK2HCLS1CSF2RBCTNNB1CCND3SDCBPPIK3R2PTPN11STAT1LYNJAK1


Description

No description

Comments

GenMAPP notes 
NetPath 17 - IL-5 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP127(r20949) with a 90% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
86933view13:06, 15 July 2016MkutmonOntology Term : 'interleukin-5 signaling pathway' added !
68558view22:43, 5 July 2013MaintBotUpdated to 2013 gpml schema
40716view21:52, 1 March 2011MaintBotRemoved redundant pathway information and comments
33995view18:36, 9 December 2009MaintBotAutomatic update of empty xrefs
32536view13:01, 17 August 2009MaintBotFixed text labels
31234view19:46, 13 August 2009MaintBotFixed text labels
30656view22:35, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AKT1GeneProduct490878 (Entrez Gene)
ALOX5GeneProduct477753 (Entrez Gene)
ALOX5APGeneProduct477323 (Entrez Gene)
ATF2GeneProduct478806 (Entrez Gene)
BAXGeneProduct403523 (Entrez Gene)
BTKGeneProduct492019 (Entrez Gene)
CBLGeneProduct
CCND3GeneProduct608847 (Entrez Gene)
CDKN1BGeneProduct403429 (Entrez Gene)
CRKLGeneProduct608125 (Entrez Gene)
CSF2RBGeneProduct481276 (Entrez Gene)
CTNNB1GeneProduct477032 (Entrez Gene)
DNM2GeneProduct484949 (Entrez Gene)
ELK1GeneProduct491860 (Entrez Gene)
FOXO3AGeneProduct
GRB2GeneProduct483312 (Entrez Gene)
GSK3AGeneProduct484476 (Entrez Gene)
GSK3BGeneProduct478575 (Entrez Gene)
HCKGeneProduct485828 (Entrez Gene)
HCLS1GeneProduct
HRASGeneProduct
HRASGeneProduct403735 (Entrez Gene)
ICAM1GeneProduct403975 (Entrez Gene)
ICAM3GeneProduct
IL2RBGeneProduct403439 (Entrez Gene)
IL5GeneProduct403790 (Entrez Gene)
IL5RAGeneProduct476553 (Entrez Gene)
ITGAMGeneProduct489928 (Entrez Gene)
ITGB2GeneProduct403770 (Entrez Gene)
JAK1GeneProduct442952 (Entrez Gene)
JAK2GeneProduct484185 (Entrez Gene)
JUNGeneProduct609429 (Entrez Gene)
LYNGeneProduct477886 (Entrez Gene)
MAP2K2GeneProduct611939 (Entrez Gene)
MAPK14GeneProduct403856 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
MAPK9GeneProduct474652 (Entrez Gene)
NFKB1GeneProduct442859 (Entrez Gene)
NFKBIAGeneProduct480291 (Entrez Gene)
PIK3CGGeneProduct483266 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PIK3R2GeneProduct609956 (Entrez Gene)
PIM1GeneProduct481772 (Entrez Gene)
PLA2G4AGeneProduct480048 (Entrez Gene)
PRKCBGeneProduct489968 (Entrez Gene)
PRKCDGeneProduct494005 (Entrez Gene)
PTK2BGeneProduct486102 (Entrez Gene)
PTPN11GeneProduct477488 (Entrez Gene)
PTPN6GeneProduct486717 (Entrez Gene)
RAC1GeneProduct403955 (Entrez Gene)
RAF1GeneProduct484648 (Entrez Gene)
RAP1GAPGeneProduct
RAPGEF1GeneProduct491286 (Entrez Gene)
RPS6KA1GeneProduct487353 (Entrez Gene)
SDCBPGeneProduct482977 (Entrez Gene)
SH2B2GeneProduct489820 (Entrez Gene)
SHC1GeneProduct490439 (Entrez Gene)
SHC2GeneProduct611955 (Entrez Gene)
SOCS1GeneProduct490006 (Entrez Gene)
SOX4GeneProduct
STAT1GeneProduct488449 (Entrez Gene)
STAT3GeneProduct490967 (Entrez Gene)
STAT5AGeneProduct490968 (Entrez Gene)
STAT5BGeneProduct490969 (Entrez Gene)
SYKGeneProduct484196 (Entrez Gene)
UNC119GeneProduct491169 (Entrez Gene)
VAV1GeneProduct485016 (Entrez Gene)
YWHAZGeneProduct475864 (Entrez Gene)

Annotated Interactions

No annotated interactions
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