Alanine and aspartate metabolism (Homo sapiens)

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1, 2L-Alanyl-tRNACitrate cycle (TCA cycle)ProteinFatty acid metabolismSelenoamino acid metabolismbeta-Alanine metabolismUrea cycel and metabolism of amino groupsAdenylosuccinateMalate6.3.4.41.4.3.15N-Carbamoyl-L-aspartate5.1.1.1D-Ala metabolismtRNA (Asn)PC1.4.3.2GAD1tRNA(Asp)6.3.5.4Histidine metabolism3.5.1.72.6.1.14tRNA (Asn)6.3.5.6Glycine, serine and threonine metabolism3.5.1.1ASL1.2.1.18FumarateNicotinate and nicotinamide metabolism1.4.3.16Nicotinate and nicotinamide metabolismMalonate semialdehydeASPA6.1.1.22GOT1D-AlanineDARSCyanoamino acid metabolismL-ArgininosuccinateGPT3.5.1.33.5.1.38D-aspartate2.1.3.2OxaloacetateCarnosineASS2-Oxoglutarate6.1.1.7Citric acid6.3.2.11SuccinateL-AlanineGOT2Arginine and Proline metabolismL-Asparagine acidLysine biosynthesis6.3.1.14.3.1.11.4.3.1Glycolysis & gluconeogenesisL-aspartateDARSL-Asparagine acidAcetyl-CoAN-Acetyl-L-aspartateO-Acetylcarnitine2.6.1.12Pyruvate2.6.1.184.1.1.12Reductive carboxylate cycle (CO2 fixation)b-AlanineGAD2Reductive carboxylate cycle (CO2 fixation)3.4.13.35.1.1.13Pantothenate and CoA biosynthesis2-Oxosuccinamate2.3.1.7ABATPyrimidine metabolismL-Asparagine4.3.2.2AGXTL-Aspartic acid4.1.1.11


Description

Converted from rat to human using ortholog information. Link to original KEGG map: http://www.genome.ad.jp/dbget-bin/show pathway?rno00252. Edited by Sebastien Burel.

Quality Tags

Ontology Terms

 

Bibliography

  1. Wu G; ''Intestinal mucosal amino acid catabolism.''; J Nutr, 1998 PubMed
  2. Curien G, Bastien O, Robert-Genthon M, Cornish-Bowden A, Cárdenas ML, Dumas R; ''Understanding the regulation of aspartate metabolism using a model based on measured kinetic parameters.''; Mol Syst Biol, 2009 PubMed

History

View all...
CompareRevisionActionTimeUserComment
94196view14:39, 25 August 2017Mkutmonadded missing metabolite identifier
92993view18:20, 21 July 2017Khanspersfixed unconnected
92992view18:17, 21 July 2017KhanspersModified description
92991view18:17, 21 July 2017Khanspersremoved GenMAPP notes
92892view18:57, 14 July 2017EgonwAdded a missing metabolite ID.
92891view18:51, 14 July 2017EgonwReplace a CAS number for a totally different compound with the ChEBI ID for L-alanine.
92890view18:51, 14 July 2017EgonwAdded a missing metabolite ID.
91240view20:15, 21 January 2017AlexanderPicoQuick edit to datanode annotation or property
89638view06:26, 22 September 2016EgonwConnected a line (the 2nd was too hard).
74147view11:26, 1 April 2014EgonwReplaced an InChI with a more traditional identifier.
71277view22:57, 16 October 2013MaintBotUpdated UniProt/TrEMBL data source
67036view09:57, 26 June 2013Christine ChichesterOntology Term : 'alanine, aspartate and glutamate metabolic pathway' added !
63140view19:17, 8 May 2013MaintBotUpdating GPML version
54702view13:23, 7 December 2012AndraRDF Tidy
53476view23:01, 7 November 2012Andra
45055view19:43, 6 October 2011AlexanderPicoadded db refs for metabolites
45039view18:57, 6 October 2011AlexanderPicoadded EC number refs
44946view12:32, 6 October 2011MartijnVanIerselOntology Term : 'amino acid metabolic pathway' added !
41117view23:37, 1 March 2011MaintBotRemoved redundant pathway information and comments
38938view22:12, 24 September 2010Khanspersoverhaul of metabolites, pathway links and connectors
38933view21:50, 24 September 2010KhanspersPeriodical save, work in progress
38931view21:40, 24 September 2010KhanspersPeriodical save, work in progress
38925view21:30, 24 September 2010KhanspersPeriodical save, work in progress
38922view21:19, 24 September 2010KhanspersPeriodical save, work in progress
38921view21:09, 24 September 2010Khanspers
38826view10:24, 24 September 2010MartijnVanIersellinked pathway
38640view11:36, 23 September 2010MartijnVanIerselpathway link
35516view13:51, 12 February 2010MichielAdded ref
35424view10:53, 12 February 2010AndraAdded reference
34472view18:34, 10 December 2009MaintBotAutomatic update of empty xrefs
32205view12:40, 15 August 2009MaintBotFixed text labels
31692view11:47, 14 August 2009MaintBotFixed group labels
20905view11:30, 14 November 2008MaintBot[[Pathway:Homo sapiens:Alanine and aspartate metabolism KEGG]] moved to [[Pathway:WP106]]: Moved to stable identifier
14689view19:24, 23 May 2008KhanspersPeriodical save, work in progress
14686view19:14, 23 May 2008KhanspersPeriodical save, work in progress
14684view19:02, 23 May 2008Khanspersconnectors
14682view18:57, 23 May 2008Khanspersconnectors
14679view18:47, 23 May 2008KhanspersPeriodical save, work in progress
14677view18:37, 23 May 2008Khanspersconnectors
14675view18:27, 23 May 2008KhanspersConnectors
14672view18:17, 23 May 2008KhanspersPeriodical save, work in progress
14670view18:07, 23 May 2008Khansperstest
14668view17:59, 23 May 2008KhanspersAdded connectors
14665view17:30, 23 May 2008KhanspersAdded connectors
13037view11:10, 17 May 2008MaintBotautomated metabolite conversion
7890view13:46, 7 January 2008MaintBot[[Pathway:Human:Alanine and aspartate metabolism KEGG]] moved to [[Pathway:Homo sapiens:Alanine and aspartate metabolism KEGG]]: Renaming species
7570view16:00, 18 December 2007MaintBotfixed category names
7328view12:42, 4 November 2007MaintBotAdded categories to GPML
6292view22:17, 22 May 2007L.M.FerranteUploaded from wpi.php

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1.2.1.18GeneProduct1.2.1.18 (Enzyme Nomenclature)
1.4.3.1GeneProduct1.4.3.1 (Enzyme Nomenclature)
1.4.3.15GeneProduct1.4.3.15 (Enzyme Nomenclature)
1.4.3.16GeneProduct1.4.3.16 (Enzyme Nomenclature)
1.4.3.2GeneProduct1.4.3.2 (Enzyme Nomenclature)
2-OxoglutarateMetaboliteC00026 (KEGG Compound)
2-OxosuccinamateMetaboliteCHEBI:57735 (ChEBI)
2.1.3.2GeneProduct2.1.3.2 (Enzyme Nomenclature)
2.3.1.7GeneProduct2.3.1.7 (Enzyme Nomenclature)
2.6.1.12GeneProduct2.6.1.12 (Enzyme Nomenclature)
2.6.1.14GeneProduct2.6.1.14 (Enzyme Nomenclature)
2.6.1.18GeneProduct2.6.1.18 (Enzyme Nomenclature)
3.4.13.3GeneProduct3.4.13.3 (Enzyme Nomenclature)
3.5.1.1GeneProduct3.5.1.1 (Enzyme Nomenclature)
3.5.1.3GeneProduct3.5.1.3 (Enzyme Nomenclature)
3.5.1.38GeneProduct3.5.1.38 (Enzyme Nomenclature)
3.5.1.7GeneProduct3.5.1.7 (Enzyme Nomenclature)
4.1.1.11GeneProduct4.1.1.11 (Enzyme Nomenclature)
4.1.1.12GeneProduct4.1.1.12 (Enzyme Nomenclature)
4.3.1.1GeneProduct4.3.1.1 (Enzyme Nomenclature)
4.3.2.2GeneProduct4.3.2.2 (Enzyme Nomenclature)
5.1.1.13GeneProduct5.1.1.13 (Enzyme Nomenclature)
5.1.1.1GeneProduct5.1.1.1 (Enzyme Nomenclature)
6.1.1.22GeneProduct6.1.1.22 (Enzyme Nomenclature)
6.1.1.7GeneProduct6.1.1.7 (Enzyme Nomenclature)
6.3.1.1GeneProduct6.3.1.1 (Enzyme Nomenclature)
6.3.2.11GeneProduct6.3.2.11 (Enzyme Nomenclature)
6.3.4.4GeneProduct6.3.4.4 (Enzyme Nomenclature)
6.3.5.4GeneProduct6.3.5.4 (Enzyme Nomenclature)
6.3.5.6GeneProduct6.3.5.6 (Enzyme Nomenclature)
ABATGeneProduct18 (Entrez Gene)
AGXTGeneProduct189 (Entrez Gene)
ASLGeneProduct435 (Entrez Gene)
ASPAGeneProduct443 (Entrez Gene)
ASSGeneProduct445 (Entrez Gene)
Acetyl-CoAMetabolite72-89-9 (CAS) Acetyl-CoA
AdenylosuccinateMetaboliteCHEBI:15919 (ChEBI)
Arginine and Proline metabolismPathway
CarnosineMetabolite305-84-0 (CAS) Carnosine
Citric acidMetaboliteHMDB00094 (HMDB)
Cyanoamino acid metabolismPathway
D-Ala metabolismPathway
D-AlanineMetabolite338-69-2 (CAS) D-Alanine
D-aspartateMetaboliteC00402 (KEGG Compound)
DARSGeneProduct1615 (Entrez Gene)
Fatty acid metabolismPathwayWP143 (WikiPathways)
FumarateMetaboliteC00122 (KEGG Compound)
GAD1GeneProduct2571 (Entrez Gene)
GAD2GeneProduct2572 (Entrez Gene)
GOT1GeneProduct2805 (Entrez Gene)
GOT2GeneProduct2806 (Entrez Gene)
GPTGeneProduct2875 (Entrez Gene)
Glycine, serine and threonine metabolismPathway
Glycolysis & gluconeogenesisPathwayWP534 (WikiPathways)
Histidine metabolismPathway
L-AlanineMetaboliteCHEBI:16977 (ChEBI)
L-ArgininosuccinateMetaboliteCHEBI:15682 (ChEBI)
L-Asparagine acidMetabolite70-47-3 (CAS)
L-AsparagineMetabolite70-47-3 (CAS) L-Asparagine
L-Aspartic acidMetaboliteC00049 (KEGG Compound)
L-aspartateMetaboliteC00049 (KEGG Compound)
Lysine biosynthesisPathway
MalateMetabolite617-48-1 (CAS) (S)-Malate
Malonate semialdehydeMetabolite33190 (ChEBI)
N-Acetyl-L-aspartateMetaboliteQ28000013 (Wikidata)
N-Carbamoyl-L-aspartateMetabolite15859 (ChEBI)
Nicotinate and nicotinamide metabolismPathway
O-AcetylcarnitineMetabolite3040-38-8 (CAS)
OxaloacetateMetaboliteC00036 (KEGG Compound)
PCGeneProduct5091 (Entrez Gene)
Pantothenate and CoA biosynthesisPathway
Pyrimidine metabolismPathway
PyruvateMetabolite32816 (ChEBI)
Reductive carboxylate cycle (CO2 fixation)Pathway
Selenoamino acid metabolismPathway
SuccinateMetaboliteC00042 (KEGG Compound)
Urea cycel and metabolism of amino groupsPathwayWP497 (WikiPathways)
b-AlanineMetabolite6912-68-1 (CAS) beta-alanine
beta-Alanine metabolismPathway
tRNA (Asn)GeneProduct
tRNA(Asp)GeneProduct

Annotated Interactions

No annotated interactions

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