Synthesis and Degradation of Ketone Bodies (Drosophila melanogaster)

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1Fatty acid beta-oxidationAcetoacetateFatty acid metabolismAcetoacetyl-CoAHOMOLOGY MAPPGlycolysis3-Hydroxy-butyrate(HMG-CoA cycle)Acetyl-CoA* pathway-regulated enzymes: HMG-CoA synthase, mtSterol biosynthesisAcetyl-CoAPyruvate metabolism3-Hydroxy-3-methylglutaryl-CoACG10399HMGCS2CG10932CG1140BDH


Ketone bodies are three water-soluble compounds that are produced as by-products when fatty acids are broken down for energy in the liver and kidney. They are used as a source of energy in the heart and brain. In the brain, they are a vital source of energy during fasting. Source: Wikipedia


GenMAPP notes 
Ketogenesis (Human)
GenMAPP remarks 
Adapted from KEGG

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Ontology Terms



  1. Fukao T, Lopaschuk GD, Mitchell GA; ''Pathways and control of ketone body metabolism: on the fringe of lipid biochemistry.''; Prostaglandins Leukot Essent Fatty Acids, 2004 PubMed Europe PMC


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79360view19:16, 21 March 2015Khanspersupdate
79359view19:15, 21 March 2015KhanspersReverted to version '11:47, 26 June 2013' by Khanspers
71525view19:22, 17 October 2013MaintBotAutomated update of data sources
68729view22:04, 6 July 2013MaintBotUpdated to 2013 gpml schema
67671view11:47, 26 June 2013DdiglesOntology Term : 'ketone bodies metabolic pathway' added !
40905view22:35, 1 March 2011MaintBotRemoved redundant pathway information and comments
35380view09:19, 12 February 2010Thomasadded literature
35369view09:15, 12 February 2010ThomasModified description
20895view11:30, 14 November 2008MaintBot[[Pathway:Drosophila melanogaster:Synthesis and Degradation of Ketone Bodies KEGG]] moved to [[Pathway:WP101]]: Moved to stable identifier
8627view14:05, 7 January 2008MaintBotAdded to category $category
8625view14:05, 7 January 2008N.ReyesUploaded new pathway

External references


NameTypeDatabase referenceComment
BDHGeneProduct (Entrez Gene)
CG10399GeneProduct33978 (Entrez Gene)
CG10932GeneProduct31695 (Entrez Gene)
CG1140GeneProduct38261 (Entrez Gene)
HMGCS2GeneProduct (Entrez Gene)

Annotated Interactions

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