Statin pathway (WP921)

Pan troglodytes

What are statins? See Wikipedia at: http://en.wikipedia.org/wiki/Statin More about this pathway and statins: https://www.pharmgkb.org/do/serve?objId=PA2031&objCls=Pathway
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Authors

Thomas Kelder , Daniela Digles , and Eric Weitz

Cited In

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Organism

Communities

Annotations

Pathway Ontology: statin drug pathway

Participants

Label Type Compact Identifier Comment
Phospholipid Metabolite kegg.compound:C00865
VLDL Metabolite kegg.compound:C01834
Cholesterol ester Metabolite kegg.compound:C02530
Acetyl-CoA Metabolite hmdb:HMDB0001206
IDL Metabolite kegg.compound:C01834
HDL Metabolite kegg.compound:C01834
Fatty acid Metabolite kegg.compound:C00162
LDL Metabolite kegg.compound:C01834
Triglyceride Metabolite kegg.compound:C00422
ABCA1 GeneProduct ncbigene:464630
APOA1 GeneProduct ncbigene:451564
APOA4 GeneProduct ncbigene:466792
APOC2 GeneProduct ncbigene:744578
APOC3 GeneProduct ncbigene:451563
APOC1 GeneProduct ncbigene:743864
CYP7A1 GeneProduct ncbigene:464191
SCARB1 GeneProduct ncbigene:452359
PLTP GeneProduct ncbigene:458291
LCAT GeneProduct ncbigene:743056
LDLR GeneProduct ncbigene:455722
DGAT1 GeneProduct ncbigene:464460
LPL GeneProduct ncbigene:464031
LIPC GeneProduct ncbigene:746925
SOAT1 GeneProduct ncbigene:457553
APOE GeneProduct ncbigene:449586
LRP1 GeneProduct ncbigene:452006
CETP GeneProduct ncbigene:467982
HMGCR GeneProduct ncbigene:471516
Download TSV Query Drugst.One

References

  1. Direct effects of statins on cells primarily involved in atherosclerosis. Chen H, Ikeda U, Shimpo M, Shimada K. Hypertens Res. 2000 Mar;23(2):187–92. PubMed Europe PMC Scholia