Blood clotting cascade (WP887)
Pan troglodytes
Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: [[wikipedia:Coagulation|Wikipedia]]
Authors
Thomas Kelder , Christine Chichester , and Eric WeitzCited In
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Organism
Communities
Annotations
Pathway Ontology: coagulation cascade pathway
Participants
Label | Type | Compact Identifier | Comment |
---|---|---|---|
F12 | GeneProduct | ncbigene:462304 | |
F11 | GeneProduct | ncbigene:461643 | |
F9 | GeneProduct | ncbigene:465887 | |
F10 | GeneProduct | ncbigene:452679 | |
F10 | GeneProduct | ncbigene:452679 | |
VWF | GeneProduct | ncbigene:451773 | |
F5 | GeneProduct | ncbigene:457500 | |
F7 | GeneProduct | ncbigene:744785 | |
F2 | GeneProduct | ncbigene:451158 | |
F13B | GeneProduct | ncbigene:735857 | |
PLAU | GeneProduct | ncbigene:738078 | |
PLAT | GeneProduct | ncbigene:472748 | |
SERPINB2 | GeneProduct | ncbigene:739078 | |
SERPINE1 | GeneProduct | ncbigene:472467 | |
PLG | GeneProduct | ncbigene:463117 | |
FGB | GeneProduct | ncbigene:461558 | |
FGA | GeneProduct | ncbigene:461559 | |
FGG | GeneProduct | ncbigene:461560 | |
F8 | GeneProduct | ncbigene:473838 |
References
- The current status of coagulation. Luchtman-Jones L, Broze GJ Jr. Ann Med. 1995 Feb;27(1):47–52. PubMed Europe PMC Scholia