Blood clotting cascade (WP887)

Pan troglodytes

Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: [[wikipedia:Coagulation|Wikipedia]]
last edited


Thomas Kelder , Christine Chichester , and Eric Weitz

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Pathway Ontology: coagulation cascade pathway


Label Type Compact Identifier Comment
F12 GeneProduct ncbigene:462304
F11 GeneProduct ncbigene:461643
F9 GeneProduct ncbigene:465887
F10 GeneProduct ncbigene:452679
F10 GeneProduct ncbigene:452679
VWF GeneProduct ncbigene:451773
F5 GeneProduct ncbigene:457500
F7 GeneProduct ncbigene:744785
F2 GeneProduct ncbigene:451158
F13B GeneProduct ncbigene:735857
PLAU GeneProduct ncbigene:738078
PLAT GeneProduct ncbigene:472748
SERPINB2 GeneProduct ncbigene:739078
SERPINE1 GeneProduct ncbigene:472467
PLG GeneProduct ncbigene:463117
FGB GeneProduct ncbigene:461558
FGA GeneProduct ncbigene:461559
FGG GeneProduct ncbigene:461560
F8 GeneProduct ncbigene:473838


  1. The current status of coagulation. Luchtman-Jones L, Broze GJ Jr. Ann Med. 1995 Feb;27(1):47–52. PubMed Europe PMC Scholia