G protein signaling pathways (WP813)
Gallus gallus
G proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades. G proteins are so called because they function as "molecular switches". They alternate from 'inactive' guanosine diphosphate (GDP) to 'active' guanosine triphosphate (GTP), which is a binding state, and which proceeds to regulate downstream cell processes. Source: [[wikipedia:G_protein|Wikipedia]]
Authors
Thomas Kelder , Christine Chichester , Lauren J. Dupuis , and Eric WeitzCited In
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Organism
Gallus gallusCommunities
Annotations
Pathway Ontology: G protein mediated signaling pathway
Participants
Label | Type | Compact Identifier | Comment |
---|---|---|---|
IP3 | Metabolite | hmdb:HMDB0001143 | |
Ca2+ | Metabolite | hmdb:HMDB0000464 | |
DAG | Metabolite | kegg.compound:C00165 | |
cAMP | Metabolite | hmdb:HMDB0000058 | |
PRKAR2B | GeneProduct | ncbigene:769420 | |
GNG10 | GeneProduct | ncbigene:769603 | |
PDE7B | GeneProduct | ncbigene:421692 | |
ADCY3 | GeneProduct | ncbigene:422013 | |
ADCY5 | GeneProduct | ncbigene:395340 | |
GNG12 | GeneProduct | ncbigene:772239 | |
GNG11 | GeneProduct | ncbigene:771999 | |
AKAP8 | GeneProduct | ncbigene:426167 | |
AKAP1 | GeneProduct | ncbigene:417668 | |
PRKAR1B | GeneProduct | ncbigene:416446 | |
GNAS | GeneProduct | ncbigene:419313 | |
PRKCD | GeneProduct | ncbigene:415905 | |
GNB3 | GeneProduct | ncbigene:427945 | |
RCJMB04_23b22 | GeneProduct | ncbigene:427262 | |
GNAO1 | GeneProduct | ncbigene:415698 | |
PRKCB | GeneProduct | ncbigene:416567 | |
GNA14 | GeneProduct | ncbigene:431611 | |
AKAP5 | GeneProduct | ncbigene:428917 | |
GNAZ | GeneProduct | ncbigene:770226 | |
PDE8B | GeneProduct | ncbigene:427645 | |
NRAS | GeneProduct | ncbigene:419885 | |
GNG13 | GeneProduct | ncbigene:771014 | |
PRKAR1A | GeneProduct | ncbigene:417438 | |
GNA11 | GeneProduct | ncbigene:374077 | |
PRKCH | GeneProduct | ncbigene:423518 | |
PPP3CA | GeneProduct | ncbigene:395113 | |
GNAI1 | GeneProduct | ncbigene:396368 | |
CALM1 | GeneProduct | ncbigene:396523 | |
PRKACB | GeneProduct | ncbigene:424542 | |
PRKAR2A | GeneProduct | ncbigene:416062 | |
GNB5 | GeneProduct | ncbigene:415417 | |
KCNJ3 | GeneProduct | ncbigene:396369 | |
AKAP7 | GeneProduct | ncbigene:426926 | |
GNA13 | GeneProduct | ncbigene:417434 | |
PDE1A | GeneProduct | ncbigene:424116 | |
PDE1C | GeneProduct | ncbigene:420752 | |
ADCY2 | GeneProduct | ncbigene:420935 | |
GNAO1 | GeneProduct | ncbigene:415698 | |
GNAL | GeneProduct | ncbigene:474379 | |
RCJMB04_12k21 | GeneProduct | ncbigene:423302 | |
PRKD3 | GeneProduct | ncbigene:421478 | |
ADCY9 | GeneProduct | ncbigene:395339 | |
AKAP6 | GeneProduct | ncbigene:423314 | |
ADCY1 | GeneProduct | ncbigene:420788 | |
AKAP13 | GeneProduct | ncbigene:415502 | |
PDE8A | GeneProduct | ncbigene:415455 | |
AKAP12 | GeneProduct | ncbigene:421634 | |
RHOA | GeneProduct | ncbigene:395442 | |
GNAI3 | GeneProduct | ncbigene:374097 | |
AKAP11 | GeneProduct | ncbigene:418835 | |
PRKCE | GeneProduct | ncbigene:421409 | |
RCJMB04_6n13 | GeneProduct | ncbigene:419402 | |
RCJMB04_5a10 | GeneProduct | ncbigene:417430 | |
RCJMB04_16p24 | GeneProduct | ncbigene:424991 | |
GNG5 | GeneProduct | ncbigene:424538 | |
HRAS | GeneProduct | ncbigene:396229 | |
PRKCZ | GeneProduct | ncbigene:419399 | |
AKAP10 | GeneProduct | ncbigene:417612 | |
GNAI1 | GeneProduct | ncbigene:396368 | |
ADCY8 | GeneProduct | ncbigene:420328 | |
ADCY7 | GeneProduct | ncbigene:415732 | |
PDE4B | GeneProduct | ncbigene:424700 | |
KRAS | GeneProduct | ncbigene:418207 | |
PDE7A | GeneProduct | ncbigene:425199 | |
AKAP9 | GeneProduct | ncbigene:395695 | |
GNG4 | GeneProduct | ncbigene:771582 | |
GNA12 | GeneProduct | ncbigene:769924 | |
ITPR1 | GeneProduct | ncbigene:395412 | |
SLC9A1 | GeneProduct | ncbigene:419580 | |
GNAI2 | GeneProduct | ncbigene:396367 |
References
- G proteins: a family of signal transducers. Stryer L, Bourne HR. Annu Rev Cell Biol. 1986;2:391–419. PubMed Europe PMC Scholia
- G protein pathways. Neves SR, Ram PT, Iyengar R. Science. 2002 May 31;296(5573):1636–9. PubMed Europe PMC Scholia