The [[wikipedia:citric_acid_cycle|citric acid cycle]], also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle, (or rarely, the Szent-Gyorgyi-Krebs cycle) is a series of enzyme-catalysed chemical reactions of central importance in all living cells that use oxygen as part of cellular respiration. In eukaryotes, the citric acid cycle occurs in the matrix of the mitochondrion. The components and reactions of the citric acid cycle were established by seminal work from both [[wikipedia:Albert_Szent-Gyorgyi|Albert Szent-Gyorgyi]] and [[wikipedia:Hans_Krebs|Hans Krebs]]. Source: Wikipedia ([[wikipedia:citric_acid_cycle]]) Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP78 CPTAC Assay Portal].

Authors

Kdahlquist , Martijn Van Iersel , Alex Pico , Thomas Kelder , Nick Fidelman , Kristina Hanspers , Ray Andrews II , Harm Nijveen , Miranda Stobbe , Sander Houten , Daniela Digles , Egon Willighagen , Denise Slenter , Finterly Hu , and Eric Weitz

Cited In

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Organism

Homo sapiens

Communities

Annotations

Pathway Ontology: citric acid cycle pathway classic metabolic pathway citric acid cycle pathway

Participants

References

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