Blood clotting cascade (WP775)

Gallus gallus

Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: [[wikipedia:Coagulation|Wikipedia]]
last edited


Thomas Kelder , Christine Chichester , and Eric Weitz

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Gallus gallus



Pathway Ontology: coagulation cascade pathway


Label Type Compact Identifier Comment
F11 GeneProduct ncbigene:422723
F9 GeneProduct ncbigene:374258
F10 GeneProduct ncbigene:395876
F10 GeneProduct ncbigene:395876
VWF GeneProduct ncbigene:419031
F5 GeneProduct ncbigene:374052
F7 GeneProduct ncbigene:395086
F2 GeneProduct ncbigene:395306
F13B GeneProduct ncbigene:424355
SERPINF2 GeneProduct ncbigene:417561
PLAU GeneProduct ncbigene:396424
PLAT GeneProduct ncbigene:426791
SERPINB2 GeneProduct ncbigene:420896
PLG GeneProduct ncbigene:421580
FGB GeneProduct ncbigene:373926
FGA GeneProduct ncbigene:396307
FGG GeneProduct ncbigene:395837
F8 GeneProduct ncbigene:422199


  1. The current status of coagulation. Luchtman-Jones L, Broze GJ Jr. Ann Med. 1995 Feb;27(1):47–52. PubMed Europe PMC Scholia