G proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades. G proteins are so called because they function as "molecular switches". They alternate from 'inactive' guanosine diphosphate (GDP) to 'active' guanosine triphosphate (GTP), which is a binding state, and which proceeds to regulate downstream cell processes. Source: [[wikipedia:G_protein|Wikipedia]]

Authors

Nathan Salomonis , Bruce Conklin , Charles Redfern , Thomas Kelder , Christine Chichester , Lauren J. Dupuis , and Eric Weitz

Cited In

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Organism

Rattus norvegicus

Communities

Annotations

Pathway Ontology: G protein mediated signaling pathway

Participants

References

1. Stryer L, Bourne HR. G proteins: a family of signal transducers. Annu Rev Cell Biol. 1986;2:391–419. PubMed Europe PMC Scholia
2. Neves SR, Ram PT, Iyengar R. G protein pathways. Science. 2002 May 31;296(5573):1636–9. PubMed Europe PMC Scholia