Leptin and adiponectin (WP683)
Mus musculus
Proposed mechanism by which leptin and adiponectin stimulate fatty acid oxidation. Adapted from fig 1 in [http://www.ncbi.nlm.nih.gov/pubmed/16497175 Dyck et al.].
Authors
Thomas Kelder and Egon WillighagenCited In
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Organism
Mus musculusCommunities
Annotations
Disease Ontology: glucose metabolism disease
Pathway Ontology: leptin system pathway adiponectin signaling pathway
Participants
Label | Type | Compact Identifier | Comment |
---|---|---|---|
Fatty acid | Metabolite | chebi:35366 | |
Fatty acid | Metabolite | chebi:35366 | |
Acetyl-CoA | Metabolite | chebi:15351 | |
Malonyl-CoA | Metabolite | chebi:15531 | |
Adipor1 | GeneProduct | ncbigene:72674 | |
Prkaa1 | GeneProduct | ncbigene:105787 | |
Prkab1 | GeneProduct | ncbigene:19079 | |
Leptin | GeneProduct | ncbigene:16846 | |
Adipor2 | GeneProduct | ncbigene:68465 | |
Acc1 | GeneProduct | ncbigene:107476 | |
Prkag1 | GeneProduct | ncbigene:19082 | |
Lepr | GeneProduct | ncbigene:16847 | |
Cpt1 | GeneProduct | ncbigene:12894 | |
Adiponectin | GeneProduct | ncbigene:11450 |
References
- Dyck DJ, Heigenhauser GJF, Bruce CR. The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity. Acta Physiol (Oxf). 2006 Jan;186(1):5–16. PubMed Europe PMC Scholia