DNA replication (WP565)
Drosophila melanogaster
DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "replication" in that each strand of the original double-stranded DNA molecule serves as template for the reproduction of the complementary strand. Hence, following DNA replication, two identical DNA molecules have been produced from a single double-stranded DNA molecule. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication. Source: [[wikipedia:DNA_replication|Wikipedia]]
Authors
Kdahlquist , David Koren , Thomas Kelder , Egon Willighagen , Christine Chichester , and Eric WeitzCited In
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Organism
Drosophila melanogasterCommunities
Annotations
Pathway Ontology: DNA replication pathway
Participants
Label | Type | Compact Identifier | Comment |
---|---|---|---|
CG9273 | GeneProduct | ncbigene:35364 | |
DNApol-alpha180 | GeneProduct | ncbigene:42553 | |
DNApol-alpha50 | GeneProduct | ncbigene:38942 | |
DNAprim | GeneProduct | ncbigene:44915 | |
Pole2 | GeneProduct | ncbigene:38661 | |
DNApol-epsilon | GeneProduct | ncbigene:42758 | |
lat | GeneProduct | ncbigene:36454 | |
Orc2 | GeneProduct | ncbigene:41703 | |
Orc5 | GeneProduct | ncbigene:34794 | |
Orc4 | GeneProduct | ncbigene:37970 | |
Orc1 | GeneProduct | ncbigene:35686 | |
Orc6 | GeneProduct | ncbigene:36017 | |
dup | GeneProduct | ncbigene:47121 | |
RpL40 | GeneProduct | ncbigene:33629 | |
Mcm6 | GeneProduct | ncbigene:31603 | |
Mcm5 | GeneProduct | ncbigene:41296 | |
dpa | GeneProduct | ncbigene:35679 | |
Mcm3 | GeneProduct | ncbigene:31449 | |
Mcm2 | GeneProduct | ncbigene:40973 | |
Mcm7 | GeneProduct | ncbigene:39014 | |
Mcm10 | GeneProduct | ncbigene:35390 | |
DNApol-alpha73 | GeneProduct | ncbigene:43278 | |
RfC3 | GeneProduct | ncbigene:34423 | |
CG8142 | GeneProduct | ncbigene:32763 | |
RfC38 | GeneProduct | ncbigene:34550 | |
RfC40 | GeneProduct | ncbigene:38492 | |
Gnf1 | GeneProduct | ncbigene:40607 | |
mus209 | GeneProduct | ncbigene:37290 | |
l(1)G0148 | GeneProduct | ncbigene:31598 | |
RpA-70 | GeneProduct | ncbigene:40972 | |
CDC45L | GeneProduct | ncbigene:31052 | |
CG12018 | GeneProduct | ncbigene:38228 | |
DNApol-delta | GeneProduct | ncbigene:39746 | |
CG5971 | GeneProduct | ncbigene:38989 | |
Ubi-p63E | GeneProduct | ncbigene:38456 |
References
- Regulation of chromosome replication. Kelly TJ, Brown GW. Annu Rev Biochem. 2000;69:829–80. PubMed Europe PMC Scholia
- DNA replication in eukaryotic cells. Bell SP, Dutta A. Annu Rev Biochem. 2002;71:333–74. PubMed Europe PMC Scholia