Biogenic amine synthesis (WP550)
Homo sapiens
Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source: http://www.whatislife.com/reader2/Metabolism/pathway/Neurotransmitter.html Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP550 CPTAC Assay Portal]
Authors
Alex Pico , Kristina Hanspers , Thomas Kelder , Martijn Van Iersel , Christine Chichester , Egon Willighagen , Chris Evelo , AAR&Co , Martina Summer-Kutmon , Eric Weitz , and Finterly HuCited In
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Organism
Homo sapiensCommunities
Annotations
Pathway Ontology: biogenic amine biosynthetic pathway amine neurotransmitter metabolic pathway
Participants
Label | Type | Compact Identifier | Comment |
---|---|---|---|
Choline | Metabolite | cas:62-49-7 | |
Epinephrine | Metabolite | hmdb:HMDB0000068 | |
5-hydroxy-tryptophan | Metabolite | cas:4350-09-8 | |
Acetylserotonin | Metabolite | cas:1210-83-9 | |
GABA | Metabolite | hmdb:HMDB0000112 | |
L-DOPA | Metabolite | cas:59-92-7 | |
Histidine | Metabolite | cas:71-00-1 | |
Dopamine | Metabolite | cas:62-31-7 | |
Acetylcholine | Metabolite | cas:51-84-3 | |
Tyrosine | Metabolite | cas:60-18-4 | |
Serotonin | Metabolite | cas:50-67-9 | |
Phenylalanine | Metabolite | cas:63-91-2 | |
Melatonin | Metabolite | hmdb:HMDB0001389 | |
Glutamate | Metabolite | cas:56-86-0 | |
Tryptophan | Metabolite | cas:73-22-3 | |
Norepinephrine | Metabolite | cas:51-41-2 | |
Histamine | Metabolite | cas:51-45-6 | |
GAD2 | GeneProduct | ncbigene:2572 | |
DDC | GeneProduct | ncbigene:1644 | |
TPH1 | GeneProduct | ncbigene:7166 | |
HDC | GeneProduct | ncbigene:3067 | |
DBH | GeneProduct | ncbigene:1621 | |
DDC | GeneProduct | ncbigene:1644 | |
TH | GeneProduct | ncbigene:7054 | |
PNMT | GeneProduct | ncbigene:5409 | |
ACHE | GeneProduct | ncbigene:43 | |
COMT | GeneProduct | ncbigene:1312 | |
PAH | GeneProduct | ncbigene:5053 | |
CHAT | GeneProduct | ncbigene:1103 | |
AANAT | GeneProduct | ncbigene:15 | |
GAD1 | GeneProduct | ncbigene:2571 | |
MAOA | GeneProduct | ncbigene:4128 | |
ASMT | GeneProduct | ncbigene:438 | |
MAOA | GeneProduct | ncbigene:4128 | |
DDC | GeneProduct | ncbigene:1644 |
References
- Purves D. Neuroscience [Internet]. Sinauer Associates Incorporated; 2001. 709 p. Available from: https://books.google.com/books/about/Neuroscience.html?hl=&id=t9iGQgAACAAJ OpenLibrary Worldcat