Overview of purine metabolism; metabolic markers are highlighted in red, with graphical arrows indicating if a marker is present in higher or lower concentrations compared to normal (healthy) levels. This pathway was inspired by Chapter 13, edition 5 of the book of Blau (in press). The full version of this PW including disorders, based on ed. 4, can be found [https://www.wikipathways.org/index.php/Pathway:WP4224 here]. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP4792 CPTAC Assay Portal]

Authors

Denise Slenter , Martina Summer-Kutmon , Lauren J. Dupuis , Finterly Hu , and Egon Willighagen

Cited In

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Organism

Homo sapiens

Communities

Inherited Metabolic Disorders (IMD) Pathways Rare Diseases

Annotations

Pathway Ontology: purine metabolic pathway

Participants

References

1. Su HC, Lenardo MJ. Combined Immune Deficiencies. In: Stiehm’s Immune Deficiencies [Internet]. Elsevier; 2014. p. 143–69. Available from: http://dx.doi.org/10.1016/B978-0-12-405546-9.00005-4 DOI
2. Blau N, Duran M, Gibson KM, Vici CD. Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases [Internet]. Springer; 2014. 867 p. Available from: https://play.google.com/store/books/details?id=t9i6BQAAQBAJ OpenLibrary Worldcat