Acetylcholine is an important neurotransmitter. It can be rapidly released in the synaptic cleft upon activation of the neuron. In the synaptic cleft the compound is degraded rapidly into choline and acetate, this is essential for proper neuronal functioning. Choline and Acetate are taken up into the cytosol and recycled for the next activation.

Authors

Andrew Kwa , Thomas Kelder , Christine Chichester , Martina Summer-Kutmon , Egon Willighagen , Friederike Ehrhart , Lauren J. Dupuis , and Eric Weitz

Cited In

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Organism

Danio rerio

Communities

Annotations

Pathway Ontology: acetylcholine metabolic pathway

Participants

References

1. Choline and cholinergic neurons. Blusztajn JK, Wurtman RJ. Science. 1983 Aug 12;221(4611):614–20. PubMed Europe PMC Scholia