Ketone bodies synthesis and degradation (WP427)
Caenorhabditis elegans
Ketone bodies are three water-soluble compounds that are produced as by-products when fatty acids are broken down for energy in the liver and kidney. They are used as a source of energy in the heart and brain. In the brain, they are a vital source of energy during fasting. Source: [[wikipedia:Ketone_bodies|Wikipedia]]
Authors
Niradiz Reyes , Thomas Kelder , Daniela Digles , Egon Willighagen , Kristina Hanspers , and Eric WeitzCited In
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Organism
Caenorhabditis elegansCommunities
Annotations
Pathway Ontology: ketone bodies metabolic pathway
Participants
Label | Type | Compact Identifier | Comment |
---|---|---|---|
3-Hydroxy-butyrate | Metabolite | chebi:37054 | |
Acetoacetate | Metabolite | chebi:13705 | |
3-Hydroxy-3-methylglutaryl-CoA | Metabolite | chebi:11814 | |
Acetyl-CoA | Metabolite | chebi:15351 | |
Acetyl-CoA | Metabolite | chebi:15351 | |
Acetoacetyl-CoA | Metabolite | chebi:15345 | |
kat-1 | GeneProduct | ncbigene:174161 | |
HMGCS2 | GeneProduct | ncbigene: | |
Y71G12B.10 | GeneProduct | ncbigene:171738 | |
C05C10.3 | GeneProduct | ncbigene:174548 | |
BDH | GeneProduct | ncbigene: |
References
- Pathways and control of ketone body metabolism: on the fringe of lipid biochemistry. Fukao T, Lopaschuk GD, Mitchell GA. Prostaglandins Leukot Essent Fatty Acids. 2004 Mar;70(3):243–51. PubMed Europe PMC Scholia