Metabolism overview (WP3602)
Homo sapiens
High level overview of human metabolism, including fatty acid biosynthesis, beta-oxidation, ketone metabolism, citric acid cycle, urea cycle, transamination, and glycogen metabolism.
Authors
Claire Lemmens , Egon Willighagen , Jonathan Mélius , Denise Slenter , Friederike Ehrhart , and Eric WeitzCited In
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Organism
Homo sapiensCommunities
Annotations
Pathway Ontology: classic metabolic pathway
Participants
| Label | Type | Compact Identifier | Comment |
|---|---|---|---|
| Oxaloacetic acid | Metabolite | kegg.compound:C00036 | |
| Pyruvic acid | Metabolite | kegg.compound:C00022 | |
| Fructose-1,6-biphosphate | Metabolite | kegg.compound:C05345 | |
| UDP-glucose | Metabolite | kegg.compound:C00029 | |
| Carbonyl phosphate | Metabolite | kegg.compound:C00169 | |
| 2-Phosphoglycerate | Metabolite | kegg.compound:C00631 | |
| Glyceraldehyde3-phosphate | Metabolite | kegg.compound:C05345 | |
| Oxaloacetic acid | Metabolite | kegg.compound:C00036 | |
| 2-trans-hexadecenoyl-ACP | Metabolite | kegg.compound:C05763 | |
| Malonyl-CoA | Metabolite | kegg.compound:C00083 | |
| Glutamine | Metabolite | kegg.compound:C00064 | |
| Glutamic acid | Metabolite | kegg.compound:C00025 | |
| Malic acid | Metabolite | kegg.compound:C00149 | |
| Alanine | Metabolite | kegg.compound:C00133 | |
| Sedoheptulose7-phosphate | Metabolite | kegg.compound:C05382 | |
| Palmitoyl carnitine | Metabolite | kegg.compound:C02990 | |
| α-Amino acid | Metabolite | kegg.compound:C00151 | |
| Glycerol | Metabolite | kegg.compound:C00116 | |
| Argininosuccinic | Metabolite | chebi:15682 | |
| Lysophosphatic acid | Metabolite | kegg.compound:C00681 | |
| 6-phosphonicacid | Metabolite | pubchem.compound:91493 | |
| Diacylglycerol | Metabolite | kegg.compound:C00641 | |
| glycerol-3-phosphate | Metabolite | kegg.compound:C00093 | |
| Fructase-6-phosphate | Metabolite | kegg.compound:C00085 | |
| 3-hydroxy-CoA hexadecanoyl | Metabolite | kegg.compound:C05258 | |
| 3-Oxo-hexadecanoyl-ACP | Metabolite | kegg.compound:C05762 | |
| 1,3-Biphosphoglyceric | Metabolite | kegg.compound:C00236 | |
| Fatty acid | Metabolite | kegg.compound:C00162 | |
| Xylulose5-phosphate | Metabolite | kegg.compound:C00231 | |
| Glutamic acid | Metabolite | kegg.compound:C00025 | |
| 3-phosphoglycerate | Metabolite | kegg.compound:C00197 | |
| Citrulline | Metabolite | kegg.compound:C00327 | |
| Fructose-2,6-biphosphate | Metabolite | pubchem.compound:105021 | |
| Succinic Acid | Metabolite | kegg.compound:C00042 | |
| 3-Hydroxy-hexadecanoyl-ACP | Metabolite | kegg.compound:C04633 | |
| Aspartic acid | Metabolite | kegg.compound:C00049 | |
| Citric acid | Metabolite | kegg.compound:C00158 | |
| Oxaloacetic acid | Metabolite | kegg.compound:C00036 | |
| Octanoyl-ACP | Metabolite | kegg.compound:C05752 | |
| 3-oxo-palmitoyl-CoA | Metabolite | kegg.compound:C05259 | |
| Malonyl ACP | Metabolite | kegg.compound:C01209 | |
| MonoacylglycerolMAG | Metabolite | kegg.compound:C01885 | |
| Pyruvic acid | Metabolite | kegg.compound:C00022 | |
| Glyceraldehyde-3-phosphate | Metabolite | kegg.compound:C00118 | |
| 6-Phospho-gluconelactone | Metabolite | pubchem.compound:439452 | |
| Urea | Metabolite | kegg.compound:C00086 | |
| 2-Oxo acid | Metabolite | kegg.compound:C00161 | |
| Erythrose4-phosphate | Metabolite | kegg.compound:C05382 | |
| NH3 | Metabolite | kegg.compound:C00014 | |
| Fatty acyl CoA | Metabolite | kegg.compound:C00040 | |
| 2-Oxoglutaric | Metabolite | kegg.compound:C00026 | |
| Palmitoyl-CoA | Metabolite | kegg.compound:C00154 | |
| TriacylglycerolTAG | Metabolite | kegg.compound:C00422 | |
| Glucose | Metabolite | kegg.compound:C00031 | |
| Ribulose5-phosphate | Metabolite | kegg.compound:C00199 | |
| Acetyl Coenzyme A | Metabolite | kegg.compound:C00024 | |
| Palmitic acid | Metabolite | wikidata:Q209727 | |
| Phosphatidic acid | Metabolite | kegg.compound:C00416 | |
| Palmitoyl-ACP | Metabolite | kegg.compound:C05764 | |
| 2-oxo acid | Metabolite | kegg.compound:C00611 | |
| Acetyl-ACP | Metabolite | kegg.compound:C03939 | |
| Oxaoacetic acid | Metabolite | kegg.compound:C00036 | |
| Glucose-6-phosphatase | Metabolite | kegg.compound:C00668 | |
| 2-trans-hexadecenoyl-CoA | Metabolite | kegg.compound:C05272 | |
| Glycogen | Metabolite | kegg.compound:C00182 | |
| Glyceraldehyde-3-phosphate | Metabolite | kegg.compound:C00118 | |
| Aspartic acid | Metabolite | kegg.compound:C00036 | |
| Phosphoenolpyruvaat | Metabolite | kegg.compound:C00074 | |
| Malic acid | Metabolite | kegg.compound:C00149 | |
| Dihydroxy acetonephosphate | Metabolite | kegg.compound:C00111 | |
| Acetyl Coenzyme A | Metabolite | kegg.compound:C00024 | |
| Ribose-5-phosphate | Metabolite | kegg.compound:C00117 | |
| Acetoacetyl-CoA | Metabolite | kegg.compound:C00332 | |
| Arginine | Metabolite | kegg.compound:C00062 | |
| Citric acid | Metabolite | kegg.compound:C00158 | |
| Glucose-1-phosphate | Metabolite | kegg.compound:C00103 | |
| Diacylglycerol | Metabolite | kegg.compound:C00641 | |
| Pyruvic acid | Metabolite | kegg.compound:C00022 | |
| Aspartic acid | Metabolite | kegg.compound:C00036 | |
| α-amino acid | Metabolite | kegg.compound:C00151 | |
| Malic acid | Metabolite | kegg.compound:C00149 | |
| glycerol-3-phosphate | Metabolite | kegg.compound:C00093 | |
| Dihydroxy acetonephosphate | Metabolite | kegg.compound:C00111 | |
| Fructase-6-phosphate | Metabolite | kegg.compound:C00085 | |
| Tetradecanoyl-ACP | Metabolite | kegg.compound:C05761 | |
| 2-trans-tetradecanoyl-ACP | Metabolite | kegg.compound:C05761 | |
| 3-hydroxy-tetradecanoyl-ACP | Metabolite | kegg.compound:C04688 | |
| 3-oxo-tetradecanoyl-ACP | Metabolite | kegg.compound:C05759 | |
| Dodecanoyl-ACP | Metabolite | kegg.compound:C05223 | |
| 2-trans-dodecanoyl-ACP | Metabolite | kegg.compound:C05758 | |
| 3-hydroxy-dodecanoyl-ACP | Metabolite | kegg.compound:C05757 | |
| 3-oxo-dodecanoyl-ACP | Metabolite | kegg.compound:C05756 | |
| Decanoyl-ACP | Metabolite | kegg.compound:C05755 | |
| 2-trans-decanoyl-ACP | Metabolite | kegg.compound:C05754 | |
| 3-hydroxy-decanoyl-ACP | Metabolite | kegg.compound:C04619 | |
| 3-oxo-decanoyl-ACP | Metabolite | kegg.compound:C05753 | |
| 2-trans-octenoyl-ACP | Metabolite | kegg.compound:C05751 | |
| 3-Hydroxy-octenoyl-ACP | Metabolite | kegg.compound:C04620 | |
| 3-oxo-octanoyl-ACP | Metabolite | kegg.compound:C05750 | |
| Hexanoyl-ACP | Metabolite | kegg.compound:C05749 | |
| 2-trans-hexanoyl-ACP | Metabolite | kegg.compound:C05748 | |
| 3-Hydroxy hexanoyl-ACP | Metabolite | kegg.compound:C05747 | |
| 3-oxo-hexanoyl-ACP | Metabolite | kegg.compound:C05746 | |
| Butyryl-ACP | Metabolite | kegg.compound:C05745 | |
| 2-trans-butenoyl-ACP | Metabolite | kegg.compound:C04618 | |
| 2-hydroxy-butyryl-ACP | Metabolite | kegg.compound:C04618 | |
| Acetoacetyl-ACP | Metabolite | kegg.compound:C05744 | |
| Pyruvic acid | Metabolite | kegg.compound:C00022 | |
| Palmitoyl carnitine | Metabolite | kegg.compound:C02990 | |
| Palmitoyl-CoA | Metabolite | kegg.compound:C00154 | |
| Tetradecanoyl-CoA | Metabolite | kegg.compound:C02593 | |
| 2-trans-tetradecanoyl-CoA | Metabolite | kegg.compound:C05273 | |
| 3-hydroxy-tetradecanoyl-CoA | Metabolite | kegg.compound:C05260 | |
| 3-oxo-tetradecanoyl-CoA | Metabolite | kegg.compound:C05261 | |
| Dodecanoyl-CoA | Metabolite | kegg.compound:C01832 | |
| 2-trans-dodecanoyl-CoA | Metabolite | kegg.compound:C03221 | |
| 3-hydroxy-dodecanoyl-CoA | Metabolite | kegg.compound:C05262 | |
| 3-oxo-dodecanoyl-CoA | Metabolite | kegg.compound:C05261 | |
| Decanoyl-CoA | Metabolite | kegg.compound:C05274 | |
| 2-trans-decanoyl-CoA | Metabolite | kegg.compound:C05275 | |
| 3-hydroxy-decanoyl-CoA | Metabolite | kegg.compound:C05264 | |
| 3-oxo-decanoyl-CoA | Metabolite | kegg.compound:C05265 | |
| Octanoyl-CoA | Metabolite | kegg.compound:C01944 | |
| 2-trans-octenoyl-CoA | Metabolite | kegg.compound:C05276 | |
| 3-Hydroxy-octenoyl-CoA | Metabolite | kegg.compound:C05266 | |
| 3-oxo-octanoyl-CoA | Metabolite | kegg.compound:C05267 | |
| Hexanoyl-CA | Metabolite | kegg.compound:C05270 | |
| 2-trans-hexanoyl-CoA | Metabolite | kegg.compound:C05271 | |
| 3-Hydroxy hexanoyl-CoA | Metabolite | kegg.compound:C05268 | |
| 3-oxo-hexanoyl-CoA | Metabolite | kegg.compound:C05269 | |
| Butyryl-CoA | Metabolite | kegg.compound:C00136 | |
| 2-trans-butenoyl-CoA | Metabolite | kegg.compound:C00877 | |
| 2-hydroxy-butyryl-CoA | Metabolite | kegg.compound:C01144 | |
| Acetoacetyl-CoA | Metabolite | kegg.compound:C00332 | |
| Pyruvic acid | Metabolite | kegg.compound:C00022 | |
| Acetoacetic Acid | Metabolite | kegg.compound:C00164 | |
| Succinyl-CoA | Metabolite | kegg.compound:C00091 | |
| Acetoacetyl-CoA | Metabolite | kegg.compound:C00332 | |
| HMG-CoA | Metabolite | kegg.compound:C00356 | |
| Acetoacetic acid | Metabolite | kegg.compound:C00164 | |
| Acetone | Metabolite | kegg.compound:C00207 | |
| 3-hydroxybutyric acid | Metabolite | kegg.compound:C01089 | |
| Isocitric acid | Metabolite | kegg.compound:C00311 | |
| 2-Oxoglutaric acid | Metabolite | kegg.compound:C00026 | |
| Succinyl-CoA | Metabolite | kegg.compound:C00091 | |
| Succinic acid | Metabolite | kegg.compound:C00042 | |
| Fumaric acid | Metabolite | kegg.compound:C00122 | |
| Malic acid | Metabolite | kegg.compound:C00122 | |
| Oxaloacetic acid | Metabolite | kegg.compound:C00122 | |
| Glyoxylic acid | Metabolite | kegg.compound:C00048 | |
| Oxaloacetic acid | Metabolite | kegg.compound:C00036 | |
| α-Amino acid | Metabolite | kegg.compound:C00151 | |
| 2-Oxo acid | Metabolite | kegg.compound:C00161 | |
| α-Amino acid | Metabolite | kegg.compound:C00151 | |
| α-Amino acid | Metabolite | kegg.compound:C00151 | |
| 2-Oxo acid | Metabolite | kegg.compound:C00161 | |
| 2-Oxo acid | Metabolite | kegg.compound:C00161 | |
| α-Amino acid | Metabolite | kegg.compound:C00151 | |
| 2-Oxo acid | Metabolite | kegg.compound:C00161 | |
| Aspartic acid | Metabolite | kegg.compound:C00036 | |
| 2-Oxo acid | Metabolite | kegg.compound:C00161 | |
| α-Amino acid | Metabolite | kegg.compound:C00151 | |
| 2-Oxoglutaric acid | Metabolite | kegg.compound:C00026 | |
| Fumaric acid | Metabolite | kegg.compound:C00122 | |
| Ornithine | Metabolite | kegg.compound:C00077 |