Ketone bodies synthesis and degradation (WP311)
Ketone bodies are three water-soluble compounds (acetoacetate, beta-hydroxybutyrate, and the spontaneous breakdown product of acetoacetate, acetone) that are produced as by-products when fatty acids are broken down for energy in the liver and kidney. They are used as a source of energy in the heart and brain. In the brain, they are a vital source of energy during fasting. Source: [[wikipedia:Ketone_bodies|Wikipedia]]
AuthorsNiradiz Reyes , Thomas Kelder , Kristina Hanspers , Adrien Defay , Daniela Digles , Chris Evelo , Egon Willighagen , and Eric Weitz
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- Identification of high‐dimensional omics‐derived predictors for tumor growth dynamics using machine learning and pharmacometric modeling (2021).
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Pathway Ontologyketone bodies biosynthetic pathway ketone bodies degradation pathway ketone bodies metabolic pathway
- Pathways and control of ketone body metabolism: on the fringe of lipid biochemistry. Fukao T, Lopaschuk GD, Mitchell GA. Prostaglandins Leukot Essent Fatty Acids. 2004 Mar;70(3):243–51. PubMed Europe PMC Scholia