G13 signaling pathway (WP298)
Mus musculus
The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: [[wikipedia:G12/G13_alpha_subunits|Wikipedia]]
Authors
Anita Chow , Thomas Kelder , Christine Chichester , Kristina Hanspers , Egon Willighagen , and Eric WeitzCited In
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Organism
Mus musculusCommunities
Annotations
Pathway Ontology: G protein mediated signaling pathway via Galpha12/Galpha13 family
Participants
| Label | Type | Compact Identifier | Comment |
|---|---|---|---|
| Limk1 | GeneProduct | ncbigene:16885 | |
| Gna13 | GeneProduct | ncbigene:14674 | |
| Arhgef1 | GeneProduct | ncbigene:16801 | |
| Rhoa | GeneProduct | ncbigene:11848 | |
| Pik3r2 | GeneProduct | ncbigene:18709 | |
| Diap1 | GeneProduct | ncbigene:13367 | |
| Pfn1 | GeneProduct | ncbigene:18643 | |
| Pip4k2a | GeneProduct | ncbigene:18718 | |
| Mapk10 | GeneProduct | ncbigene:26414 | |
| Pkn1 | GeneProduct | ncbigene:320795 | |
| Mybph | GeneProduct | ncbigene:53311 | |
| Ppp1cb | GeneProduct | ncbigene:19046 | |
| Arhgdib | GeneProduct | ncbigene:11857 | |
| Rac1 | GeneProduct | ncbigene:19353 | |
| Map3k4 | GeneProduct | ncbigene:26407 | |
| Pak3 | GeneProduct | ncbigene:18481 | |
| Myl1 | GeneProduct | ncbigene:17901 | |
| Cit | GeneProduct | ncbigene:12704 | |
| Iqgap1 | GeneProduct | ncbigene:29875 | |
| Iqgap2 | GeneProduct | ncbigene:544963 | |
| Rps6kb1 | GeneProduct | ncbigene:72508 | A41687 |
| Rock1 | GeneProduct | ncbigene:19877 | S69211 |
| Rock2 | GeneProduct | ncbigene:19878 | BAA31594 |
| Sh3rf1 | GeneProduct | ncbigene:59009 | Posh |
| Pik3ca | GeneProduct | ncbigene:18706 | |
| Pik3cb | GeneProduct | ncbigene:74769 | |
| Pik3cd | GeneProduct | ncbigene:18707 | P42338 |
| Cfl2 | GeneProduct | ncbigene:12632 | |
| Cfl1 | GeneProduct | ncbigene:12631 | |
| Rtkn | GeneProduct | ncbigene:20166 | |
| Rhpn2 | GeneProduct | ncbigene:52428 | |
| Arhgdig | GeneProduct | ncbigene:14570 | |
| Calm1 | GeneProduct | ncbigene:12313 | |
| Tnk2 | GeneProduct | ncbigene:51789 | S33596 |
| Cdc42 | GeneProduct | ncbigene:12540 | |
| Wasl | GeneProduct | ncbigene:73178 | |
| Was | GeneProduct | ncbigene:22376 | |
| Sra1 | GeneProduct | ncbigene:24068 |
References
- Neves SR, Ram PT, Iyengar R. G protein pathways. Science. 2002 May 31;296(5573):1636–9. PubMed Europe PMC Scholia