HIF1A and PPARG regulation of glycolysis (WP2456)
Homo sapiens
Hypoxia-inducible factor 1A and peroxisome proliferator activated receptor gamma play a role in regulating glycolysis. This pathway is part the [https://assays.cancer.gov/available_assays?wp_id=WP2456 CPTAC Assay Portal].
Authors
M Aguirre , Jonathan Mélius , Chris Evelo , Kristina Hanspers , Friederike Ehrhart , Alex Pico , and Finterly HuCited In
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Organism
Homo sapiensCommunities
Annotations
Pathway Ontology: regulatory pathway glycolysis/gluconeogenesis pathway
Participants
| Label | Type | Compact Identifier | Comment |
|---|---|---|---|
| Glyceraldehyde-3-phosphate | Metabolite | kegg.compound:C00118 | |
| Pyruvate | Metabolite | kegg.compound:C00022 | |
| Fructose-1,6-biphosphate | Metabolite | kegg.compound:C05378 | |
| Dihydroxyacetonephosphate | Metabolite | kegg.compound:C00111 | |
| Lactate | Metabolite | kegg.compound:C00186 | |
| Glycerol-3-phosphate | Metabolite | kegg.compound:C00093 | |
| Lysophosphatidate | Metabolite | kegg.compound:C00681 | |
| Triacylglycerol | Metabolite | kegg.compound:C00422 | |
| Diacylglycerol | Metabolite | kegg.compound:C00165 | |
| Glucose | Metabolite | kegg.compound:C00031 | |
| GAPDH | GeneProduct | ensembl:ENSG00000111640 | |
| LDHA | GeneProduct | ensembl:ENSG00000134333 | |
| TPI1 | GeneProduct | ensembl:ENSG00000111669 | |
| GPD1 | GeneProduct | ensembl:ENSG00000167588 | |
| GPAT3 | GeneProduct | ensembl:ENSG00000138678 | |
| SLC2A1 | GeneProduct | ensembl:ENSG00000117394 | |
| PPARG | GeneProduct | ensembl:ENSG00000132170 | |
| HIF1A | GeneProduct | ensembl:ENSG00000100644 | |
| HIF1A | GeneProduct | ensembl:ENSG00000100644 |