Effects of nitric oxide (WP1995)
NO (Nitric oxide) is an important signalling molecule with vasodilatory and anti-inflammatory effects, indicating a postive role in reducing hypertension and cardiovascular disease. At the same time, NO is also associated with health risks such as increased risk in carcinogenesis, and hypoxia in infants. It has been suggested that NO can also increase mitochondrial efficiency. NO can be formed from L-Arginine through the classic Arginine-NO-Synthase pathway, or it can be formed directly from dietary nitrite by deoxiginated globins.
AuthorsMartijn Van Iersel , Alex Pico , Martina Summer-Kutmon , and Eric Weitz
Discuss this pathway
- GediNET for discovering gene associations across diseases using knowledge based machine learning approach (2022).
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OrganismsHomo sapiens Micronutrients
Pathway Ontologycardiovascular system homeostasis pathway
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