DNA replication (WP192)
Caenorhabditis elegans
DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "replication" in that each strand of the original double-stranded DNA molecule serves as template for the reproduction of the complementary strand. Hence, following DNA replication, two identical DNA molecules have been produced from a single double-stranded DNA molecule. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication. Source: [[wikipedia:DNA_replication|Wikipedia]]
Authors
Kdahlquist , David Koren , Thomas Kelder , Egon Willighagen , Christine Chichester , Eric Weitz , Ulas Babayigit , Denise Slenter , and Lars WillighagenCited In
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Organism
Caenorhabditis elegansCommunities
Annotations
Pathway Ontology: DNA replication pathway
Participants
Label | Type | Compact Identifier | Comment |
---|---|---|---|
dATP | Metabolite | chebi:16284 | |
ADP | Metabolite | chebi:16761 | |
dCTP | Metabolite | chebi:16311 | |
ATP | Metabolite | chebi:15422 | |
CTP | Metabolite | chebi:17677 | |
UTP | Metabolite | chebi:15713 | |
ATP | Metabolite | chebi:15422 | |
ATP | Metabolite | chebi:15422 | |
dGTP | Metabolite | chebi:16497 | |
ADP | Metabolite | chebi:16761 | |
dUTP | Metabolite | chebi:17625 | |
ATP | Metabolite | chebi:15422 | |
GTP | Metabolite | chebi:15996 | |
mcm-7 | GeneProduct | ncbigene:178831 | |
rfc-1 | GeneProduct | ncbigene:179967 | |
F10C2.4 | GeneProduct | ncbigene:179652 | |
F33H2.5 | GeneProduct | ncbigene:173368 | |
pri-1 | GeneProduct | ncbigene:176358 | |
F34D10.2 | GeneProduct | ncbigene:175481 | |
orc-2 | GeneProduct | ncbigene:174676 | |
Y47D3A.28 | GeneProduct | ncbigene:176562 | |
div-1 | GeneProduct | ncbigene:176439 | |
pri-2 | GeneProduct | ncbigene:173122 | |
mcm-2 | GeneProduct | ncbigene:174841 | |
mcm-6 | GeneProduct | ncbigene:176385 | |
rfc-3 | GeneProduct | ncbigene:178259 | |
cdc-6 | GeneProduct | ncbigene:172029 | |
Y39A1A.12 | GeneProduct | ncbigene:176486 | |
Y47D3A.29 | GeneProduct | ncbigene:176544 | |
ubq-1 | GeneProduct | ncbigene:175840 | |
mcm-3 | GeneProduct | ncbigene:180010 | |
F08B4.5 | GeneProduct | ncbigene:177673 | |
ARPA | GeneProduct | ncbigene:176131 | |
ubq-2 | GeneProduct | ncbigene:176718 | |
CDC46 | GeneProduct | ncbigene:175552 | |
rfc-2 | GeneProduct | ncbigene:176946 | |
mcm-4 | GeneProduct | ncbigene:171793 |
References
- Rose A. Replication and repair. WormBook [Internet]. 2014 Dec 4;1–16. Available from: http://dx.doi.org/10.1895/wormbook.1.54.2 DOI
- Differential activation of the DNA replication checkpoint contributes to asynchrony of cell division in C. elegans embryos. Brauchle M, Baumer K, Gönczy P. Curr Biol. 2003 May 13;13(10):819–27. PubMed Europe PMC Scholia