Sucrose is synthesized from the precursors UDP-glucose and fructose 6-phosphate, which are converted into sucrose 6-phosphate by the enzyme sucrose-6-phosphate synthase. Sucrose 6-phosphate is then dephosphorylated by sucrose phosphatase, resulting in the formation of sucrose, which can be exported to other tissues. Although the reaction catalyzed by sucrose 6-phosphate synthase is energetically unfavorable, the hydrolysis of sucrose 6-phosphate to sucrose is highly exergonic, driving the overall synthesis of sucrose in an essentially irreversible manner.

Authors

Meredith Braymer , Alex Pico , Thomas Kelder , Egon Willighagen , Daniela Digles , Denise Slenter , and Eric Weitz

Cited In

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Organism

Saccharomyces cerevisiae

Communities

Annotations

Pathway Ontology: sucrose biosynthetic pathway

Participants

References