Adipogenesis (WP1331)

Danio rerio

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.
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last edited

Authors

Martijn Van Iersel , Kristina Hanspers , Martina Summer-Kutmon , and Egon Willighagen

Cited In

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Organism

Danio rerio

Communities

Annotations

Pathway Ontology: signaling pathway pertinent to development

Participants

Label Type Compact Identifier Comment
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rbl1 GeneProduct ncbigene:795522
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pparg GeneProduct ncbigene:557037
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MEF2B GeneProduct ncbigene:558180
mef2cb GeneProduct ncbigene:798771
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mif GeneProduct ncbigene:751093
TGFB1 GeneProduct ncbigene:359834
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zgc:109940 GeneProduct ncbigene:553553
gtf3aa GeneProduct ncbigene:445389
rb1 GeneProduct ncbigene:777733
LOC557385 GeneProduct ncbigene:557385
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adfp GeneProduct ncbigene:794841
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CDKN1A GeneProduct ncbigene:100151416
LOC567485 GeneProduct ncbigene:567485
sp1 GeneProduct ncbigene:324109
LOC100001938 GeneProduct ncbigene:100001938
GADD45A GeneProduct ncbigene:431763
GADD45B GeneProduct ncbigene:406304
cebpd GeneProduct ncbigene:140817
bmp1a GeneProduct ensembl:ENSDARG00000028071
bmp2b GeneProduct ncbigene:30632
zgc:153939 GeneProduct ncbigene:777717
bmp4 GeneProduct ncbigene:30612
FOXO1A GeneProduct ncbigene:768121
LOC100006043 GeneProduct ncbigene:100006043
ppargc1al GeneProduct ncbigene:553418
ncoa1 GeneProduct ncbigene:563288
ncoa2 GeneProduct ncbigene:81884
pparab GeneProduct ncbigene:557714
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LOC566983 GeneProduct ncbigene:566983
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mbnl1 GeneProduct ncbigene:767696
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wnt5b GeneProduct ncbigene:30105
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smad3b GeneProduct ncbigene:326283
FZD1 GeneProduct ncbigene:30365
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hnf1a GeneProduct ncbigene:266961
frzb GeneProduct ncbigene:30119
ins GeneProduct ncbigene:30262
LOC797300 GeneProduct ncbigene:797300
zgc:76966 GeneProduct ncbigene:405805
gata4 GeneProduct ncbigene:30483
nr2f1a GeneProduct ncbigene:30418
roraa GeneProduct ncbigene:564951
cugbp1 GeneProduct ncbigene:58137
hif1ab GeneProduct ncbigene:393202
copeb GeneProduct ncbigene:280650
KLF7 GeneProduct ncbigene:553670
ncor1 GeneProduct ncbigene:393246
ncor2 GeneProduct ncbigene:561503
zgc:111859 GeneProduct ncbigene:335901
egr2b GeneProduct ncbigene:30190
LOC565310 GeneProduct ncbigene:565310
epas1 GeneProduct ncbigene:555192
ahr1b GeneProduct ncbigene:554265
wwtr1 GeneProduct ncbigene:568008
si:ch211-134j6.3 GeneProduct ncbigene:563003
LOC559281 GeneProduct ncbigene:559281
zgc:123260 GeneProduct ncbigene:567403
lmna GeneProduct ncbigene:195815
AGPAT2 GeneProduct ncbigene:777624
zmpste24 GeneProduct ncbigene:334380
lpin1 GeneProduct ncbigene:799099
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pck1 GeneProduct ncbigene:378727
zgc:77867 GeneProduct ncbigene:406473
cebpa GeneProduct ncbigene:140815
e2f4 GeneProduct ncbigene:406741
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References

  1. Rosen ED, Spiegelman BM. Molecular regulation of adipogenesis. Annu Rev Cell Dev Biol. 2000;16:145–71. PubMed Europe PMC Scholia