Estrogen receptor refers to a group of receptors which are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. The main function of the estrogen receptor is as a DNA binding transcription factor which regulates gene expression. However the estrogen receptor also has additional functions independent of DNA binding.

Authors

Alex Pico , Susan Coort , and Eric Weitz

Cited In

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Organism

Danio rerio

Communities

Annotations

Pathway Ontology: estrogen signaling pathway

Participants

References