DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "replication" in that each strand of the original double-stranded DNA molecule serves as template for the reproduction of the complementary strand. Hence, following DNA replication, two identical DNA molecules have been produced from a single double-stranded DNA molecule. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication. Source: [wikipedia:DNA_replication|Wikipedia] Based on www.genomeknowledge.org

Authors

Kdahlquist , David Koren , Thomas Kelder , Christine Chichester , Egon Willighagen , Kristina Hanspers , and Eric Weitz

Cited In

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Organism

Saccharomyces cerevisiae

Communities

Annotations

Pathway Ontology: DNA replication pathway

Participants

References

1. A yeast chromosomal origin of DNA replication defined by multiple functional elements. Marahrens Y, Stillman B. Science. 1992 Feb 14;255(5046):817–23. PubMed Europe PMC Scholia
2. Regulation of chromosome replication. Kelly TJ, Brown GW. Annu Rev Biochem. 2000;69:829–80. PubMed Europe PMC Scholia
3. DNA replication in eukaryotic cells. Bell SP, Dutta A. Annu Rev Biochem. 2002;71:333–74. PubMed Europe PMC Scholia