G13 signaling pathway (WP1063)
Bos taurus
The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: [[wikipedia:G12/G13_alpha_subunits|Wikipedia]]
Authors
Thomas Kelder , Christine Chichester , Martina Summer-Kutmon , and Eric WeitzCited In
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Organism
Bos taurusCommunities
Annotations
Pathway Ontology: G protein mediated signaling pathway via Galpha12/Galpha13 family G protein mediated signaling pathway
Participants
| Label | Type | Compact Identifier | Comment |
|---|---|---|---|
| RTKN | GeneProduct | ensembl:ENSBTAG00000000490 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:6242 |
| PKN1 | GeneProduct | ensembl:ENSBTAG00000017037 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5585 |
| CFL2 | GeneProduct | ensembl:ENSBTAG00000015053 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:1073 |
| RHPN2 | GeneProduct | ensembl:ENSBTAG00000003089 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:85415 |
| RHOA | GeneProduct | ensembl:ENSBTAG00000004279 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:387 |
| PFN1 | GeneProduct | ensembl:ENSBTAG00000018312 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5216 |
| ARHGEF1 | GeneProduct | ensembl:ENSBTAG00000018912 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:9138 |
| CYFIP1 | GeneProduct | ensembl:ENSBTAG00000016894 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:23191 |
| GNA13 | GeneProduct | ensembl:ENSBTAG00000046174 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:10672 |
| IQGAP2 | GeneProduct | ensembl:ENSBTAG00000000897 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:10788 |
| IQGAP1 | GeneProduct | ensembl:ENSBTAG00000013060 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:8826 |
| PIK3CD | GeneProduct | ensembl:ENSBTAG00000018984 | P42338Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5293 |
| ARHGDIB | GeneProduct | ensembl:ENSBTAG00000006039 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:397 |
| PIK3CB | GeneProduct | ensembl:ENSBTAG00000006909 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5291 |
| SH3RF1 | GeneProduct | ensembl:ENSBTAG00000001508 | PoshHomology Mapping from Homo sapiens to Bos taurus: Original ID = L:57630 |
| LIMK1 | GeneProduct | ensembl:ENSBTAG00000044083 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:3984 |
| MYBPH | GeneProduct | ensembl:ENSBTAG00000011465 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:4608 |
| RAC1 | GeneProduct | ensembl:ENSBTAG00000009233 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5879 |
| TNK2 | GeneProduct | ensembl:ENSBTAG00000021364 | S33596Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:10188 |
| PAK3 | GeneProduct | ensembl:ENSBTAG00000015670 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5063 |
| PIP4K2A | GeneProduct | ensembl:ENSBTAG00000018033 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5305 |
| MAPK10 | GeneProduct | ensembl:ENSBTAG00000020048 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5602 |
| WASL | GeneProduct | ensembl:ENSBTAG00000004643 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:8976 |
| PIK3R2 | GeneProduct | ensembl:ENSBTAG00000002350 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5296 |
| PPP1CB | GeneProduct | ensembl:ENSBTAG00000012447 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5500 |
| WAS | GeneProduct | ensembl:ENSBTAG00000046555 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:7454 |
| MAP3K4 | GeneProduct | ensembl:ENSBTAG00000020079 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:4216 |
| MYL1 | GeneProduct | ensembl:ENSBTAG00000009707 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:4632 |
| CIT | GeneProduct | ensembl:ENSBTAG00000008963 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:11113 |
| ARHGDIG | GeneProduct | ensembl:ENSBTAG00000027854 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:398 |
| ROCK1 | GeneProduct | ensembl:ENSBTAG00000008403 | S69211Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:6093 |
| FCHSD1 | GeneProduct | ensembl:ENSBTAG00000030499 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:1729 |
| PIK3CA | GeneProduct | ensembl:ENSBTAG00000009232 | Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5290 |
| RPS6KB1 | GeneProduct | ensembl:ENSBTAG00000016851 | A41687Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:6198 |
| ROCK2 | GeneProduct | ensembl:ENSBTAG00000005847 | BAA31594Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:9475 |
References
- G protein pathways. Neves SR, Ram PT, Iyengar R. Science. 2002 May 31;296(5573):1636–9. PubMed Europe PMC Scholia