Nanoparticle triggered regulated necrosis (Homo sapiens)

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Revision as of 19:13, 17 October 2013 by MaintBot (Talk | contribs)
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Description

No description

Quality Tags

Ontology Terms

 

Bibliography

  1. Andón FT, Fadeel B; ''Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials.''; Acc Chem Res, 2012 PubMed
  2. Ma YH, Huang CP, Tsai JS, Shen MY, Li YK, Lin LY; ''Water-soluble germanium nanoparticles cause necrotic cell death and the damage can be attenuated by blocking the transduction of necrotic signaling pathway.''; Toxicol Lett, 2011 PubMed

History

View all...
CompareRevisionActionTimeUserComment
92316view08:50, 20 May 2017EgonwOntology Term : 'nanomaterial response pathway' added !
86006view00:51, 24 June 2016Khansperschanged look of pathway nodes
86000view00:30, 24 June 2016KhanspersConnected interactions, updated xrefs, assigned node types
85999view00:22, 24 June 2016Khanspersconnected lines, changed gene nodes to pathway nodes where appropriate
85026view14:21, 6 April 2016Mkutmonremove special characters and add graphical annotations instead
81068view18:23, 19 July 2015EgonwTyped ceramide as metabolite.
81067view18:22, 19 July 2015EgonwUse a ChEBI identifier instead of a Wikipedia one.
77901view14:47, 28 October 2014Bart SmeetsModified description
77900view14:47, 28 October 2014Bart SmeetsModified description
77667view12:01, 5 October 2014EgonwReplaced 'Uniprot-SwissProt' by 'Uniprot-TrEMBL'.
74182view09:32, 3 April 2014Bart SmeetsAdded wiki entries
74143view10:31, 1 April 2014Bart SmeetsExpanded description of nanoparticles in pathway, added corresponding literature references.
73826view15:05, 25 February 2014Bart SmeetsFixed some wikipedia entries
73825view15:01, 25 February 2014Bart SmeetsAdded a few GeneIDs
71447view19:13, 17 October 2013MaintBotUpdated data sources
70991view20:50, 21 September 2013EgonwAdded a few identifiers.
68057view13:10, 29 June 2013EgonwCompleted the pathway as given in the figure.
68054view13:04, 29 June 2013EgonwPeriodical save, work in progress
66148view08:19, 15 June 2013EgonwAdded the literature ref again.
65706view12:26, 11 June 2013EgonwAdded the caspase 8 identifier, and widened the Necroptosis box.
65603view16:18, 10 June 2013EgonwMore content of the pathway.
65457view10:27, 8 June 2013EgonwOntology Term : 'necrosis pathway' added !
65447view08:02, 8 June 2013EgonwNew pathway

External references

Datanodes

View all...
NameTypeDatabase referenceComment
ATPMetabolite
Arachidonic acidMetaboliteHMDB01043 (HMDB)
CASP8GeneProductENSG00000064012 (Ensembl)
CalciumMetaboliteHMDB00464 (HMDB)
Calpains
Ceramide
FADDGeneProductENSG00000168040 (Ensembl)
Ferritin
Glutaminolysis
Glycogenolysis
Glycolysis
IronMetaboliteHMDB00692 (HMDB)
JNK
Labile iron pool
Nanoparticle
Nec-1Metabolite2828334 (PubChem-compound)
NecroptosisPathway
PAMPs
PARP1GeneProductENSG00000143799 (Ensembl)
RIPK1GeneProductENSG00000137275 (Ensembl)
RIPK3GeneProductENSG00000129465 (Ensembl)
ROSMetaboliteCHEBI:26523 (ChEBI)
SMasesProtein
TNFR1GeneProduct
TNFProteinTNF (Uniprot-TrEMBL)
TRADDGeneProductENSG00000102871 (Ensembl)
TRIFGeneProduct
cPLA₂
lipoxygenase
pH ↓

Annotated Interactions

No annotated interactions

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