AMPK signaling (Homo sapiens)

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Bibliography

View all 16 references
  1. Lee WJ, Kim M, Park HS, Kim HS, Jeon MJ, Oh KS, Koh EH, Won JC, Kim MS, Oh GT, Yoon M, Lee KU, Park JY; ''AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1.; ''Biochem Biophys Res Commun, 2006 - PubMed
  2. Murgia M, Jensen TE, Cusinato M, Garcia M, Richter EA, Schiaffino S; ''Multiple signalling pathways redundantly control glucose transporter GLUT4 gene transcription in skeletal muscle.; ''J Physiol, 2009 - PubMed
  3. Findlay GM, Harrington LS, Lamb RF; ''TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation?; ''Curr Opin Genet Dev, 2005 - PubMed
  4. Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N; ''4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway.; ''Genes Dev, 1998 - PubMed
  5. Cheng A, Saltiel AR; ''More TORC for the gluconeogenic engine.; ''Bioessays, 2006 - PubMed
  6. Halse R, Fryer LG, McCormack JG, Carling D, Yeaman SJ; ''Regulation of glycogen synthase by glucose and glycogen: a possible role for AMP-activated protein kinase.; ''Diabetes, 2003 - PubMed
  7. Hue L, Beauloye C, Marsin AS, Bertrand L, Horman S, Rider MH; ''Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways.; ''J Mol Cell Cardiol, 2002 - PubMed
  8. Hahn-Windgassen A, Nogueira V, Chen CC, Skeen JE, Sonenberg N, Hay N; ''Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity.; ''J Biol Chem, 2005 - PubMed
  9. Marsin AS, Bertrand L, Rider MH, Deprez J, Beauloye C, Vincent MF, Van den Berghe G, Carling D, Hue L; ''Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia.; ''Curr Biol, 2000 - PubMed
  10. Carling D, Hardie DG; ''The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase.; ''Biochim Biophys Acta, 1989 - PubMed
  11. Hong YH, Varanasi US, Yang W, Leff T; ''AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability.; ''J Biol Chem, 2003 - PubMed
  12. Inoki K, Zhu T, Guan KL; ''TSC2 mediates cellular energy response to control cell growth and survival.; ''Cell, 2003 - PubMed
  13. Fu A, Screaton RA; ''Using kinomics to delineate signaling pathways: control of CRTC2/TORC2 by the AMPK family.; ''Cell Cycle, 2008 - PubMed
  14. Shaw RJ; ''LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.; ''Acta Physiol (Oxf), 2009 - PubMed
  15. Holmes BF, Sparling DP, Olson AL, Winder WW, Dohm GL; ''Regulation of muscle GLUT4 enhancer factor and myocyte enhancer factor 2 by AMP-activated protein kinase.; ''Am J Physiol Endocrinol Metab, 2005 - PubMed
  16. Viana R, Aguado C, Esteban I, Moreno D, Viollet B, Knecht E, Sanz P; ''Role of AMP-activated protein kinase in autophagy and proteasome function.; ''Biochem Biophys Res Commun, 2008 - PubMed

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33370view14:34, 30 November 2009MaintBotRemoved group label
33329view12:12, 24 November 2009AndraRemoved reference
33328view11:55, 24 November 2009AndraAdd reference
33179view17:41, 5 November 2009KhanspersModified categories
32864view13:52, 16 September 2009SusanModified description
32862view13:24, 16 September 2009SusanAdding literature
32861view12:52, 16 September 2009SusanSpecify description
32860view11:52, 16 September 2009SusanAdding genes
32859view08:48, 16 September 2009SusanSpecify description
32858view08:17, 16 September 2009SusanAdding genes and references
32853view12:17, 15 September 2009SusanAdding PI3 kinase
32852view11:54, 15 September 2009SusanPeriodical save, work in progress
32851view10:02, 15 September 2009SusanSpecify description
32850view09:56, 15 September 2009SusanAdding genes
32849view09:40, 15 September 2009SusanAdding genes
32848view09:33, 15 September 2009SusanPeriodical save, work in progress
32847view09:22, 15 September 2009SusanPeriodical save, work in progress
32846view09:11, 15 September 2009SusanAdding genes
32845view09:09, 15 September 2009SusanPeriodical save, work in progress
32834view11:24, 14 September 2009SusanNew pathway

Pathway Info

DataNodes

View all 47 DataNodes

Name Type Backpage Header Database reference
eEF2GeneProduct1938 (Entrez Gene)
GlucoseMetaboliteHMDB00122 (HMDB)
GLUT4GeneProduct6517 (Entrez Gene)
INSRGeneProductENSG00000171105 (Ensembl Human)
CalciumMetaboliteHMDB00464 (HMDB)
INSMetabolite (Ensembl Human)
PGC-1GeneProductENSG00000155846 (Ensembl Human)
AdiponectinMetabolite9370 (Entrez Gene)
AMPKb2GeneProduct5565 (Entrez Gene)
LeptinMetabolite
MO25GeneProduct51719 (Entrez Gene)
AMPKa1GeneProduct5562 (Entrez Gene)
HNF4AGeneProductENSG00000101076 (Ensembl Human)
AMPKb1GeneProduct5564 (Entrez Gene)
mTORGeneProduct2475 (Entrez Gene)
AMPKy1GeneProduct5571 (Entrez Gene)
AMPKa2GeneProduct5563 (Entrez Gene)
CPT1A (liver)GeneProduct1374 (Entrez Gene)
ACC1GeneProduct31 (Entrez Gene)
GEFGeneProductENSG00000125520 (Ensembl Human)
CPT1B (muscle)GeneProduct1375 (Entrez Gene)
MEF2BGeneProductENSG00000064489 (Ensembl Human)
AMPMetaboliteHMDB03540 (HMDB)
GYS1(muscle)GeneProductENSG00000104812 (Ensembl Human)
AKT1GeneProductENSG00000142208 (Ensembl Human)
GYS2 (liver)GeneProductENSG00000111713 (Ensembl Human)
Torc2GeneProduct200186 (Entrez Gene)
PFK2GeneProduct5209 (Entrez Gene)
RaptorGeneProduct57521 (Entrez Gene)
CAMKK1GeneProductENSG00000004660 (Ensembl Human)
eEF2KGeneProductENSG00000103319 (Ensembl Human)
CAMKK2GeneProductENSG00000110931 (Ensembl Human)
GeneProductGeneProduct
PLCB1GeneProductENSG00000182621 (Ensembl Human)
AMPKy2GeneProduct51422 (Entrez Gene)
STRADAGeneProductENSG00000125695 (Ensembl Human)
AMPKy3GeneProduct53632 (Entrez Gene)
STRADBGeneProductENSG00000082146 (Ensembl Human)
ACC2GeneProduct32 (Entrez Gene)
LKB1GeneProductENSG00000118046 (Ensembl Human)
Malonyl-CoAMetaboliteHMDB01175 (HMDB)
PRKACBGeneProduct5567 (Entrez Gene)
CPT1C (brain)GeneProduct126129 (Entrez Gene)
PRKACGGeneProduct5568 (Entrez Gene)
cAMPMetaboliteHMDB00058 (HMDB)
PIK3CBGeneProduct5291 (Entrez Gene)
ATPMetaboliteHMDB01532 (HMDB)
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