Portal:Reactome

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Reactome Pathways

Reactome logo

Welcome to the Reactome Portal

The Reactome Portal at WikiPathways maintains pathway content periodically synced with the Reactome collection.

Reactome is an open-source, open access, manually curated and peer-reviewed pathway database. Pathway annotations are authored by expert biologists, in collaboration with Reactome editorial staff. The rationale behind Reactome is to convey the rich information in the visual representations of biological pathways familiar from textbooks and articles in a detailed, computationally accessible format. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes and small molecules) participating in reactions form causal chain of events or pathways.

Learn more about the Reactome Website and Pathway Analysis tools

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Community Curation Initiative

In collaboration with WikiPathways, we have established a custom pathway data exchange pipeline. Reactome pathways are now incorporated into WikiPathways, an open, collaborative platform dedicated to the curation of biological pathways. We encourage you to edit, curate and create pathway content here. The Reactome team will periodically assess and selectively incorporate changes back into our centralized collection.

An open source format converter has been developed that converts Reactome pathways to the GPML format. The converter is available on GitHub.

Getting Started

Use in WikiPathways

Use in PathVisio

  • Introduction to PathVisio
  • How to started.
  • You can edit the pathways in PathVisio in the same way as in WikiPathways.
  • Download the entire collection of human Reactome pathways here and use them for pathway analysis in PathVisio.

Feel free to contact us directly with any questions.

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News and Notes

    • Nov, 2015 : Version 54 pathways now available!
    • Sep, 2015 : Version 53 pathways now available!
    • WikiPathways Curation Event on Jan 7, 2015 for curating the Reactome Collection!


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    All Pathways

    Erythrocytes take up carbon dioxide and release oxygen (Homo sapiens)

    Erythrocytes take up carbon dioxide and release oxygen
    Erythrocytes take up carbon dioxide and release oxygen

    View all Pathways for this Portal

    Download all Reactome pathways by species:


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