Portal:ExRNA/FeaturedPathways

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T-Cell Receptor and Co-stimulatory Signaling

Takahashi et al. Long non-coding RNA in liver diseases

IL1 and megakaryotyces in obesity

Beaulieu et al. Interleukin 1 receptor 1 and interleukin 1beta regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans

RNA interference

Ozpolat et al. Liposomal siRNA nanocarriers for cancer therapy Thomas et al. Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways

Extracellular vesicle-mediated signaling in recipient cells

Gangoda et al. Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?

TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer

Yang et al. Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer

mir34a and TGIF2 in osteoclastogenesis

Krzeszinski et al. miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2

mir219 in Oligodendrocyte Differentiation and Myelination

Pusic et al. Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination

Apoptosis-related network due to altered Notch3 in ovarian cancer

Hu et al. Notch3 pathway alterations in ovarian cancer

miR-222 in Exercise-Induced Cardiac Growth

Liu et al. miR-222 Is Necessary for Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

Hypoxia-mediated EMT and Stemness

van den Beucken et al. Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

DDX1 as a regulatory component of the Drosha microprocessor

Han et al. The RNA-binding protein DDX1 promotes primary microRNA maturation and inhibits ovarian tumor progression

EV release from cardiac cells and their functional effects

Danielson and Das, Extracellular Vesicles in Heart Disease: Excitement for the Future?

Rac1/Pak1/p38/MMP-2 pathway

Gonzalez-Villasana et al. Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer

eIF5A regulation in response to inhibition of the nuclear export system

Miyake et al. XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A

MFAP5-mediated ovarian cancer cell motility and invasiveness

Leung et al. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential

LncRNA-mediated mechanisms of therapeutic resistance

Parasramka et al. Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma

ApoE and miR-146 in inflammation and atherosclerosis

Li et al. Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-κB-driven inflammation and atherosclerosis

miR-148a/miR-31/FIH1/HIF1α-Notch signaling in glioblastoma

Wong et al. The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma

mir-124 predicted interactions with cell cycle and differentiation

Shields et al. A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression

miR-517 relationship with ARCN1 and USP1

Shields et al. A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression

miR-509-3p alteration of YAP1/ECM axis

Pan et al. miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

H19 action Rb-E2F1 signaling and CDK-β-catenin activity

Ohtsuka et al. H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer

mir-193a and MVP in colon cancer metastasis

Teng et al. H19 MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression

Signaling Pathways in Glioblastoma
miRs in Muscle Cell Differentiation
REBF and miR33 in cholesterol and lipid homeostasis
SRF and miRs in Smooth Muscle Differentiation and Proliferation
Mecp2 and Associated Rett Syndrome
Cell Differentiation
Endoderm Differentiation
Ectoderm Differentiation
Mesodermal Commitment Pathway
ErbB Signaling Pathway
Mir302-367 Promoting Cardiomyocyte Proliferation
Alzheimers Disease
Parkinsons Disease
MicroRNAs in cardiomyocyte hypertrophy
Integrated Lung Cancer Pathway
miRNA Biogenesis
miRNA targets in ECM and membrane receptors
Fluoropyrimidine Activity
miRNAs involved in DNA damage response
Metastatic Brain Tumor
Regulatory RNA pathways
Spinal Cord Injury
miRNA Regulation of DNA Damage Response
Parkinsons Disease Pathway (Mus musculus)
Hepatitis C and Hepatocellular Carcinoma
Metastatic brain tumor
Role of Osx and miRNAs in tooth development
miR-targeted genes in epithelium - TarBase

TarBase

miR-targeted genes in adipocytes - TarBase

TarBase

miR-targeted genes in lymphocytes - TarBase

TarBase

miR-targeted genes in muscle cell - TarBase

TarBase

miR-targeted genes in leukocytes - TarBase

TarBase

miR-targeted genes in squamous cell - TarBase

TarBase

TarBasePathway

TarBase

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