Retinol metabolism (BiGCaT, NuGO) (Homo sapiens)

From WikiPathways

Jump to: navigation, search

Contents


Curation Tags

Description

This pathway is about carotenoid metabolism. It is mainly created by the NuGO focusteam on Carotenoid metabolism. Finally it was subject to a text mining workflow which added some additional entities.


Bibliography

View all 17 references
  1. Micozzi MS, Brown ED, Edwards BK, Bieri JG, Taylor PR, Khachik F, Beecher GR, Smith JC Jr; ''Plasma carotenoid response to chronic intake of selected foods and beta-carotene supplements in men.; ''Am J Clin Nutr, 1992 - PubMed
  2. Handelman GJ, Dratz EA, Reay CC, van Kuijk JG; ''Carotenoids in the human macula and whole retina.; ''Invest Ophthalmol Vis Sci, 1988 - PubMed
  3. Khachik F, Beecher GR, Goli MB, Lusby WR, Smith JC Jr; ''Separation and identification of carotenoids and their oxidation products in the extracts of human plasma.; ''Anal Chem, 1992 - PubMed
  4. Huet F, Semama D, Maingueneau C, Charavel A, Nivelon JL; ''Vitamin A deficiency and nocturnal vision in teenagers with cystic fibrosis.; ''Eur J Pediatr, 1997 - PubMed
  5. Johansson S, Melhus H; ''Vitamin A antagonizes calcium response to vitamin D in man.; ''J Bone Miner Res, 2001 - PubMed
  6. Amir H, Karas M, Giat J, Danilenko M, Levy R, Yermiahu T, Levy J, Sharoni Y; ''Lycopene and 1,25-dihydroxyvitamin D3 cooperate in the inhibition of cell cycle progression and induction of differentiation in HL-60 leukemic cells.; ''Nutr Cancer, 1999 - PubMed
  7. Sies H, Stahl W, Sundquist AR; ''Antioxidant functions of vitamins. Vitamins E and C, beta-carotene, and other carotenoids.; ''Ann N Y Acad Sci, 1992 - PubMed
  8. Balmer JE, Blomhoff R; ''Gene expression regulation by retinoic acid.; ''J Lipid Res, 2002 - PubMed
  9. VandenLangenberg GM, Brady WE, Nebeling LC, Block G, Forman M, Bowen PE, Stacewicz-Sapuntzakis M, Mares-Perlman JA; ''Influence of using different sources of carotenoid data in epidemiologic studies.; ''J Am Diet Assoc, 1996 - PubMed
  10. Waagmeester A, Pezik P, Coort S, Tourniaire F, Evelo C, Rebholz-Schuhmann D; ''Pathway enrichment based on text mining and its validation on carotenoid and vitamin A metabolism.; ''OMICS, 2009 - PubMed
  11. Boosalis MG, Snowdon DA, Tully CL, Gross MD; ''Acute phase response and plasma carotenoid concentrations in older women: findings from the nun study.; ''Nutrition, 1996 - PubMed
  12. Ruhl CE, Everhart JE; ''Relation of elevated serum alanine aminotransferase activity with iron and antioxidant levels in the United States.; ''Gastroenterology, 2003 - PubMed
  13. Czeczuga-Semeniuk E, Wolczynski S, Markiewicz W; ''Preliminary identification of carotenoids in malignant and benign neoplasms of the breast and surrounding fatty tissue.; ''Neoplasma, 2003 - PubMed
  14. Bendich A, Olson JA; ''Biological actions of carotenoids.; ''FASEB J, 1989 - PubMed
  15. Torma H, Rollman O, Binderup L, Michaelsson G; ''Vitamin D analogs affect the uptake and metabolism of retinol by human epidermal keratinocytes in culture.; ''J Investig Dermatol Symp Proc, 1996 - PubMed
  16. Olmedilla B, Granado F, Blanco I, Rojas-Hidalgo E; ''Seasonal and sex-related variations in six serum carotenoids, retinol, and alpha-tocopherol.; ''Am J Clin Nutr, 1994 - PubMed
  17. Hidiroglou M, Williams CJ; ''Interrelationships among liposoluble vitamins in ruminants.; ''Am J Vet Res, 1986 - PubMed

Categories

History

View all
CompareRevisionActionTimeUserComment
33029view16:32, 5 October 2009AndraCorrection in the references
33028view16:28, 5 October 2009AndraNew reference
32745view23:22, 3 September 2009MaintBotModified categories
30274view20:33, 25 July 2009AlexanderPicofixed unsupported characters in Bibliography
30052view22:56, 29 June 2009AndraModified description
30049view22:33, 29 June 2009AndraAdded references
30048view22:22, 29 June 2009AndraPeriodical save, work in progress
30047view22:12, 29 June 2009AndraPeriodical save, work in progress
30046view22:07, 29 June 2009AndraAdded after text mining
30022view12:31, 26 June 2009Andraminor change
29897view11:25, 9 June 2009PaoloRomanolinked some nodes
29841view15:25, 4 June 2009AndraAdded references
29840view15:16, 4 June 2009AndraNew pathway

Pathway Info

DataNodes

View all 53 DataNodes

Name Type Backpage Header Database reference
Rbp4GeneProductRetinol binding protein 4, plasma5950 (Entrez Gene)
Rdh8UnknownRetinol dehydrogenase 850700 (Entrez Gene)
beta-cryptoxanthinMetabolitebeta-cryptoxanthinHMDB02268 (hmdbid)
RARgUnknownRARg5916 (Entrez Gene)
Sult2b1UnknownSult2b16820 (Entrez Gene)
Aldh1a2GeneProductAldehyde dehydrogenase family 1, subfamily A28854 (Entrez Gene)
RARaUnknownRARa5914 (Entrez Gene)
Npc1l1UnknownNpc1l129881 (Entrez Gene)
Rlbp1Unknown6017 (Entrez Gene)
RXRaUnknownRXRa6256 (Entrez Gene)
astaxanthinMetaboliteastaxanthinHMDB02204 (hmdbid)
Rbp7GeneProductRetinol binding protein 7, cellular116362 (Entrez Gene)
lycopeneMetabolitelycopeneHMDB03000 (hmdbid)
Abcg5UnknownAbcg564240 (Entrez Gene)
Rbp1GeneProductRetinol binding protein 1, cellular5947 (Entrez Gene)
Cd36UnknownCd36948 (Entrez Gene)
Bcmo1UnknownBcmo153630 (Entrez Gene)
Rdh10UnknownRetinol dehydrogenase 10157506 (Entrez Gene)
Rpe65Unknown6121 (RefSeq)
Rbp2GeneProductRetinol binding protein 2, cellular5948 (Entrez Gene)
RetsatGeneProductAll-trans-retinol 13,14-reductase 54884 (Entrez Gene)
Aldh1a1GeneProductAldehyde dehydrogenase family 1, subfamily A1216 (Entrez Gene)
zeaxanthinMetabolitezeaxanthinHMDB02789 (hmdbid)
Adh4GeneProductAlcohol dehydrogenase 4 (class II), pi polypeptide127 (Entrez Gene)
luteinMetaboliteluteinHMDB03233 (hmdbid)
Rdh12Unknown145226 (Entrez Gene)
Scarb1UnknownSRB1949 (Entrez Gene)
RXRgUnknownRXRg6258 (Entrez Gene)
Scarb1UnknownSRB1NP_058021 (RefSeq)
LplUnknownLpl4023 (Entrez Gene)
Cyp26b1UnknownCyp26b156603 (Entrez Gene)
Abcg8UnknownAbcg864241 (Entrez Gene)
Cyp26a1UnknownCytochrome P450 26A1 1592 (Entrez Gene)
Bcdo2GeneProductBeta-carotene 9', 10'-dioxygenase 2NP_573480 (RefSeq)
Rdh5GeneProductRetinol dehydrogenase 55959 (Entrez Gene)
RXRbUnknownRXRb6257 (Entrez Gene)
ARATGeneProduct (Entrez Gene)
Adh1GeneProductAlcohol dehydrogenase 1 (class I)124 (Entrez Gene)
RARbUnknownRARb5915 (Entrez Gene)
Crabp1GeneProductCellular retinoic acid binding protein I1381 (Entrez Gene)
Bcmo1GeneProductBeta-carotene 15,15'-monooxygenaseNP_067461 (RefSeq)
LratGeneProductLecithin-retinol acyltransferase9227 (Entrez Gene)
alpha-caroteneMetabolitealpha-caroteneHMDB03993 (hmdbid)
Aldh1a3Unknown220 (Entrez Gene)
violaxanthinMetaboliteviolaxanthinHMDB03101 (hmdbid)
Sult1a1UnknownSult1a16817 (Entrez Gene)
cryptoxanthinMetabolitecryptoxanthinHMDB02268 (hmdbid)
Crabp2GeneProductCellular retinoic acid binding protein II1382 (Entrez Gene)
canthaxanthinMetabolitecanthaxanthinHMDB03154 (hmdbid)
Cyp2e1UnknownCyp2e11571 (Entrez Gene)
Vitamin D3MetaboliteVitamin D3HMDB00876 (hmdbid)
Dhrs3GeneProductDehydrogenase/reductase (SDR family) member 39249 (Entrez Gene)
MAPKGeneProductMAPK2.7.11.24 (enzyme)
Personal tools
Navigation