GPCRs, Class A Rhodopsin-like (Homo sapiens)

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Curation Tags

Description

This pathway was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.

Ontology Tags

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
74414view10:58, 18 April 2014EgonwAdded two interactions.
74413view10:55, 18 April 2014EgonwConverted two labels into metabolite DataNodes with an identifier.
71256view21:09, 16 October 2013MaintBotAutomated update of data sources
63203view20:55, 8 May 2013MaintBotUpdating gpml version
62691view21:33, 1 May 2013MaintBotupdated uniprot data source
45338view20:22, 7 October 2011AlexanderPicoOntology Term : 'G protein mediated signaling pathway' added !
41121view23:37, 1 March 2011MaintBotRemoved redundant pathway information and comments
38917view20:53, 24 September 2010Khanspers
34571view22:02, 21 December 2009KhanspersModified description
34540view19:20, 21 December 2009KhanspersModified description
34539view19:19, 21 December 2009Khansperslayout
34538view19:18, 21 December 2009KhanspersLayout
34537view19:13, 21 December 2009KhanspersPeriodical save, work in progress
34536view19:02, 21 December 2009KhanspersModified description
34474view18:35, 10 December 2009MaintBotAutomatic update of empty xrefs
32436view17:15, 15 August 2009MaintBotFixed text labels
32106view13:47, 14 August 2009MaintBotFixed group labels
21638view11:32, 14 November 2008MaintBot[[Pathway:Homo sapiens:GPCRDB Class A Rhodopsin-like]] moved to [[Pathway:WP455]]: Moved to stable identifier
14501view00:54, 23 May 2008AlexanderPicoConnected ligands
14196view01:00, 22 May 2008AlexanderPicoFixed labels
14194view00:48, 22 May 2008AlexanderPicoPeriodical save, work in progress
14191view00:43, 22 May 2008AlexanderPicogrouped by class
13077view11:13, 17 May 2008MaintBotautomated metabolite conversion
12975view10:58, 17 May 2008MaintBotSticky edges patch by Sjoerd
8102view13:46, 7 January 2008MaintBot[[Pathway:Human:GPCRDB Class A Rhodopsin-like]] moved to [[Pathway:Homo sapiens:GPCRDB Class A Rhodopsin-like]]: Renaming species
7673view16:08, 18 December 2007MaintBotfixed category names
7416view12:42, 4 November 2007MaintBotAdded categories to GPML
19485view22:17, 22 May 2007BruceConklingpml file for [[Human:GPCRDB_Class_A_Rhodopsin-like]]
6321view22:17, 22 May 2007Nsalomonisgpml file for [[Human:GPCRDB_Class_A_Rhodopsin-like]]

External references

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NameTypeDatabase referenceComment
GPR34GeneProduct2857 (Entrez Gene)
SomatostatinMetaboliteCHEBI:64628 (ChEBI)
MTNR1AGeneProduct4543 (Entrez Gene)
CHRM1GeneProduct1128 (Entrez Gene)
OR2D2GeneProduct120776 (Entrez Gene)
CHRM2GeneProduct1129 (Entrez Gene)
SUCNR1GeneProduct56670 (Entrez Gene)
CHRM3GeneProduct1131 (Entrez Gene)
OR7C2GeneProduct26658 (Entrez Gene)
CHRM4GeneProduct1132 (Entrez Gene)
OR10H3GeneProduct26532 (Entrez Gene)
CHRM5GeneProduct1133 (Entrez Gene)
GPR4GeneProduct2828 (Entrez Gene)
ADRA1BGeneProduct147 (Entrez Gene)
GPR19GeneProduct2842 (Entrez Gene)
ADRA1AGeneProduct148 (Entrez Gene)
OpioidMetaboliteCHEBI:60598 (ChEBI)
ADRA1DGeneProduct146 (Entrez Gene)
OR2S2GeneProduct56656 (Entrez Gene)
ADRA2CGeneProduct152 (Entrez Gene)
OR8B8GeneProduct26493 (Entrez Gene)
ADRA2BGeneProduct151 (Entrez Gene)
PTGER3GeneProduct5733 (Entrez Gene)
ADRA2AGeneProduct150 (Entrez Gene)
GPR173GeneProduct54328 (Entrez Gene)
ADRB1GeneProduct153 (Entrez Gene)
LTB4RGeneProduct1241 (Entrez Gene)
ADRB2GeneProduct154 (Entrez Gene)
GPR10GeneProduct2834 (Entrez Gene)
ADRB3GeneProduct155 (Entrez Gene)
CYSLTR1GeneProduct10800 (Entrez Gene)
DRD1GeneProduct1812 (Entrez Gene)
GPR39GeneProduct2863 (Entrez Gene)
DRD5GeneProduct1816 (Entrez Gene)
OR1A1GeneProduct8383 (Entrez Gene)
DRD2GeneProduct1813 (Entrez Gene)
OR10A4GeneProduct283297 (Entrez Gene)
DRD3GeneProduct1814 (Entrez Gene)
OR2J2GeneProduct26707 (Entrez Gene)
DRD4GeneProduct1815 (Entrez Gene)
OR2A4GeneProduct79541 (Entrez Gene)
HRH1GeneProduct3269 (Entrez Gene)
OR6B1GeneProduct135946 (Entrez Gene)
HRH2GeneProduct3274 (Entrez Gene)
OR5U1GeneProduct442191 (Entrez Gene)
HRH3GeneProduct11255 (Entrez Gene)
TBXA2RGeneProduct6915 (Entrez Gene)
HTR1EGeneProduct3354 (Entrez Gene)
P2RY12GeneProduct64805 (Entrez Gene)
HTR1FGeneProduct3355 (Entrez Gene)
GPR31GeneProduct2853 (Entrez Gene)
HTR1DGeneProduct3352 (Entrez Gene)
P2RY2GeneProduct5029 (Entrez Gene)
HTR1BGeneProduct3351 (Entrez Gene)
GPR23GeneProduct2846 (Entrez Gene)
HTR1AGeneProduct3350 (Entrez Gene)
TRHRGeneProduct7201 (Entrez Gene)
HTR2BGeneProduct3357 (Entrez Gene)
GPR3GeneProduct2827 (Entrez Gene)
HTR2CGeneProduct3358 (Entrez Gene)
OR12D3GeneProduct81797 (Entrez Gene)
HTR2AGeneProduct3356 (Entrez Gene)
GPR40GeneProduct2864 (Entrez Gene)
HTR4GeneProduct3360 (Entrez Gene)
GPR65GeneProduct8477 (Entrez Gene)
HTR5AGeneProduct3361 (Entrez Gene)
BradykininMetabolite58-82-2 (CAS)
HTR6GeneProduct3362 (Entrez Gene)
OR1E1GeneProduct8387 (Entrez Gene)
HTR7GeneProduct3363 (Entrez Gene)
OR1C1GeneProduct26188 (Entrez Gene)
AGTR1GeneProduct185 (Entrez Gene)
OR2J1GeneProduct442185 (Entrez Gene)
AGTR2GeneProduct186 (Entrez Gene)
OR5V1GeneProduct81696 (Entrez Gene)
NMBRGeneProduct4829 (Entrez Gene)
OR2B3GeneProduct442184 (Entrez Gene)
BRS3GeneProduct680 (Entrez Gene)
OR2B6GeneProduct26212 (Entrez Gene)
GRPRGeneProduct2925 (Entrez Gene)
OR2F2GeneProduct135948 (Entrez Gene)
BDKRB2GeneProduct624 (Entrez Gene)
OR3A3GeneProduct8392 (Entrez Gene)
BDKRB1GeneProduct623 (Entrez Gene)
OR5F1GeneProduct338674 (Entrez Gene)
C3AR1GeneProduct719 (Entrez Gene)
OR6A2GeneProduct8590 (Entrez Gene)
GPR77GeneProduct27202 (Entrez Gene)
OR10J1GeneProduct26476 (Entrez Gene)
FPRL2GeneProduct2359 (Entrez Gene)
PTGER2GeneProduct5732 (Entrez Gene)
FPR1GeneProduct2357 (Entrez Gene)
PTGFRGeneProduct5737 (Entrez Gene)
FPRL1GeneProduct2358 (Entrez Gene)
MLNRGeneProduct2862 (Entrez Gene)
AGTRL1GeneProduct187 (Entrez Gene)
P2RY13GeneProduct53829 (Entrez Gene)
IL8RAGeneProduct3577 (Entrez Gene)
GPR27GeneProduct2850 (Entrez Gene)
IL8RBGeneProduct3579 (Entrez Gene)
CMKOR1GeneProduct57007 (Entrez Gene)
CCR1GeneProduct1230 (Entrez Gene)
GPR25GeneProduct2848 (Entrez Gene)
CCR2GeneProduct1231 (Entrez Gene)
ADORA2BGeneProduct136 (Entrez Gene)
CCR3GeneProduct1232 (Entrez Gene)
P2RY6GeneProduct5031 (Entrez Gene)
CCR4GeneProduct1233 (Entrez Gene)
P2RY11GeneProduct5032 (Entrez Gene)
CCR5GeneProduct1234 (Entrez Gene)
P2RY10GeneProduct27334 (Entrez Gene)
CCR6GeneProduct1235 (Entrez Gene)
CNR1GeneProduct1268 (Entrez Gene)
CCR8GeneProduct1237 (Entrez Gene)
GPR22GeneProduct2845 (Entrez Gene)
CCR9GeneProduct10803 (Entrez Gene)
GPR7GeneProduct2831 (Entrez Gene)
CCBP2GeneProduct1238 (Entrez Gene)
GPR17GeneProduct2840 (Entrez Gene)
CCRL2GeneProduct9034 (Entrez Gene)
GPR63GeneProduct81491 (Entrez Gene)
CXCR3GeneProduct2833 (Entrez Gene)
OR3A2GeneProduct4995 (Entrez Gene)
CXCR4GeneProduct7852 (Entrez Gene)
GPR43GeneProduct2867 (Entrez Gene)
BLR1GeneProduct643 (Entrez Gene)
GPR18GeneProduct2841 (Entrez Gene)
CX3CR1GeneProduct1524 (Entrez Gene)
GPR109BGeneProduct8843 (Entrez Gene)
CCKARGeneProduct886 (Entrez Gene)
GPR75GeneProduct10936 (Entrez Gene)
CCKBRGeneProduct887 (Entrez Gene)
HistamineMetabolite51-45-6 (CAS)
CCR10GeneProduct2826 (Entrez Gene)
Angiotensin IIMetaboliteHMDB01035 (HMDB)
CCRL1GeneProduct51554 (Entrez Gene)
OR1E2GeneProduct8388 (Entrez Gene)
CCR7GeneProduct1236 (Entrez Gene)
OR1D4GeneProduct8385 (Entrez Gene)
XCR1GeneProduct2829 (Entrez Gene)
OR1D2GeneProduct4991 (Entrez Gene)
EDNRAGeneProduct1909 (Entrez Gene)
OR1A2GeneProduct26189 (Entrez Gene)
EDNRBGeneProduct1910 (Entrez Gene)
OR1G1GeneProduct8390 (Entrez Gene)
MC1RGeneProduct4157 (Entrez Gene)
OR10A5GeneProduct144124 (Entrez Gene)
MC2RGeneProduct4158 (Entrez Gene)
OR2N1PGeneProduct26701 (Entrez Gene)
MC4RGeneProduct4160 (Entrez Gene)
OR2W1GeneProduct26692 (Entrez Gene)
MC5RGeneProduct4161 (Entrez Gene)
OR2H2GeneProduct7932 (Entrez Gene)
MC3RGeneProduct4159 (Entrez Gene)
OR2J3GeneProduct442186 (Entrez Gene)
NPY1RGeneProduct4886 (Entrez Gene)
OR2B2GeneProduct81697 (Entrez Gene)
NPY2RGeneProduct4887 (Entrez Gene)
OR2C1GeneProduct4993 (Entrez Gene)
PPYR1GeneProduct5540 (Entrez Gene)
OR2F1GeneProduct26211 (Entrez Gene)
NPY5RGeneProduct4889 (Entrez Gene)
OR2H1GeneProduct26716 (Entrez Gene)
NPY6RGeneProduct4888 (Entrez Gene)
OR3A1GeneProduct4994 (Entrez Gene)
GPR83GeneProduct10888 (Entrez Gene)
OR3A4GeneProduct390756 (Entrez Gene)
NTSR2GeneProduct23620 (Entrez Gene)
OR8D2GeneProduct283160 (Entrez Gene)
NTSR1GeneProduct4923 (Entrez Gene)
OR5I1GeneProduct10798 (Entrez Gene)
OPRD1GeneProduct4985 (Entrez Gene)
OR11A1GeneProduct26531 (Entrez Gene)
OPRK1GeneProduct4986 (Entrez Gene)
OR10H2GeneProduct26538 (Entrez Gene)
OPRM1GeneProduct4988 (Entrez Gene)
OR10H1GeneProduct26539 (Entrez Gene)
OPRL1GeneProduct4987 (Entrez Gene)
OR2T1GeneProduct26696 (Entrez Gene)
SSTR1GeneProduct6751 (Entrez Gene)
PTGER1GeneProduct5731 (Entrez Gene)
SSTR2GeneProduct6752 (Entrez Gene)
PTGDRGeneProduct5729 (Entrez Gene)
SSTR3GeneProduct6753 (Entrez Gene)
PTGER4GeneProduct5734 (Entrez Gene)
SSTR4GeneProduct6754 (Entrez Gene)
PTGIRGeneProduct5739 (Entrez Gene)
SSTR5GeneProduct6755 (Entrez Gene)
ADORA1GeneProduct134 (Entrez Gene)
F2RGeneProduct2149 (Entrez Gene)
GPR50GeneProduct9248 (Entrez Gene)
AVPR2GeneProduct554 (Entrez Gene)
MTNR1BGeneProduct4544 (Entrez Gene)
AVPR1AGeneProduct552 (Entrez Gene)
GPR87GeneProduct53836 (Entrez Gene)
AVPR1BGeneProduct553 (Entrez Gene)
P2RY14GeneProduct9934 (Entrez Gene)
OXTRGeneProduct5021 (Entrez Gene)
GPR85GeneProduct54329 (Entrez Gene)
GALR1GeneProduct2587 (Entrez Gene)
MAS1GeneProduct4142 (Entrez Gene)
GALR3GeneProduct8484 (Entrez Gene)
GPR1GeneProduct2825 (Entrez Gene)
GALR2GeneProduct8811 (Entrez Gene)
GPR24GeneProduct2847 (Entrez Gene)
F2RL1GeneProduct2150 (Entrez Gene)
GPR12GeneProduct2835 (Entrez Gene)
F2RL2GeneProduct2151 (Entrez Gene)
ADORA2AGeneProduct135 (Entrez Gene)
F2RL3GeneProduct9002 (Entrez Gene)
ADORA3GeneProduct140 (Entrez Gene)
HCRTR2GeneProduct3062 (Entrez Gene)
P2RY1GeneProduct5028 (Entrez Gene)
HCRTR1GeneProduct3061 (Entrez Gene)
P2RY4GeneProduct5030 (Entrez Gene)
GPR74GeneProduct10886 (Entrez Gene)
GPR92GeneProduct57121 (Entrez Gene)
GPR147GeneProduct64106 (Entrez Gene)
GPR174GeneProduct84636 (Entrez Gene)
GPR37GeneProduct2861 (Entrez Gene)
P2RY5GeneProduct10161 (Entrez Gene)
GPR37L1GeneProduct9283 (Entrez Gene)
GPR35GeneProduct2859 (Entrez Gene)
GPR32GeneProduct2854 (Entrez Gene)
CNR2GeneProduct1269 (Entrez Gene)
CMKLR1GeneProduct1240 (Entrez Gene)
PTAFRGeneProduct5724 (Entrez Gene)
GPR44GeneProduct11251 (Entrez Gene)
GHSRGeneProduct2693 (Entrez Gene)
GPR30GeneProduct2852 (Entrez Gene)
GPR15GeneProduct2838 (Entrez Gene)
NMUR2GeneProduct56923 (Entrez Gene)
GPR8GeneProduct2832 (Entrez Gene)
NMUR1GeneProduct10316 (Entrez Gene)
GPR6GeneProduct2830 (Entrez Gene)
FSHRGeneProduct2492 (Entrez Gene)
GPR52GeneProduct9293 (Entrez Gene)
LHCGRGeneProduct3973 (Entrez Gene)
GPR21GeneProduct2844 (Entrez Gene)
RHOGeneProduct6010 (Entrez Gene)
GPR20GeneProduct2843 (Entrez Gene)
OPN1MWGeneProduct2652 (Entrez Gene)
OR2AG1GeneProduct144125 (Entrez Gene)
OPN1LWGeneProduct5956 (Entrez Gene)
OR1D5GeneProduct8386 (Entrez Gene)
OPN1SWGeneProduct611 (Entrez Gene)
GPR45GeneProduct11250 (Entrez Gene)
OPN3GeneProduct23596 (Entrez Gene)
CYSLTR2GeneProduct57105 (Entrez Gene)
OPN4GeneProduct94233 (Entrez Gene)
GPR42GeneProduct2866 (Entrez Gene)
RRHGeneProduct10692 (Entrez Gene)
GPR41GeneProduct2865 (Entrez Gene)
RgrGeneProduct266747 (Entrez Gene)
GPR68GeneProduct8111 (Entrez Gene)
OR7A17GeneProduct26333 (Entrez Gene)
GPR171GeneProduct29909 (Entrez Gene)
Q9UDD9GeneProductQ9UDD9 (Uniprot-TrEMBL)
MAS1LGeneProduct116511 (Entrez Gene)
OR7C1GeneProduct26664 (Entrez Gene)
GPR161GeneProduct23432 (Entrez Gene)
OR7A10GeneProduct390892 (Entrez Gene)
GPR81GeneProduct27198 (Entrez Gene)
OR7A5GeneProduct26659 (Entrez Gene)
DopamineMetabolite62-31-7 (CAS)
OR1Q1GeneProduct158131 (Entrez Gene)
SerotoninMetabolite50-67-9 (CAS)
OR1I1GeneProduct126370 (Entrez Gene)
ProstaglandinMetabolite745-65-3 (CAS)
OR1F1GeneProduct4992 (Entrez Gene)
MelatoninHMDB01389 (HMDB)
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