Oxidation by Cytochrome P450 (Homo sapiens)

From WikiPathways

Jump to: navigation, search


Curation Tags

Description

Oxidation of a substrate by Cytochrome P450. Adapted from Niesink et al., Chapter 3, p. 47-48.

Ontology Tags

 

Bibliography

  1. Niesink, R.J.M, Vries, de, J., Hollinger, M.A.; ''Toxicology; Principles and Applications''; , 1996

History

View all...
CompareRevisionActionTimeUserComment
73490view23:02, 29 January 2014KhanspersModified title
73489view23:01, 29 January 2014KhanspersModified title
70584view13:57, 15 August 2013EgonwWell, Substrate-OH is not necessarily an alcohol, so marked it as a WP "Product (biology)".
70583view13:54, 15 August 2013EgonwAdded Wikpedia's "Enzyme substrate" entry as identifier for "Substrate".
70582view13:49, 15 August 2013EgonwLinked CYP to the matching Wikipedia page.
67127view10:10, 26 June 2013Christine ChichesterOntology Term : 'phase I biotransformation pathway via cytochrome P450' added !
64829view21:29, 3 June 2013MaintBotModified title
63172view20:28, 8 May 2013MaintBotUpdating gpml version
59223view20:14, 22 February 2013MaintBotUpdated Ensembl and UniProt data source
48222view05:29, 17 May 2012MaintBotAutomatic update of PubChem xrefs
44998view14:44, 6 October 2011MartijnVanIerselReverted to version '20:11, 4 June 2011' by MartijnVanIersel
43619view09:34, 10 July 2011MohhafezPeriodical save, work in progress
43178view20:11, 4 June 2011EveloOntology Term : 'xenobiotics biodegradation pathway' added !
43177view20:10, 4 June 2011EveloOntology Term : 'hepatocyte' added !
41235view23:46, 1 March 2011MaintBotRemoved redundant pathway information and comments
34480view18:38, 10 December 2009MaintBotAutomatic update of empty xrefs
32093view13:43, 14 August 2009MaintBotFixed group labels
29608view11:45, 23 May 2009MartijnVanIerselConverted to new Ensembl references
20767view11:29, 14 November 2008MaintBot[[Pathway:Homo sapiens:cytochrome P450]] moved to [[Pathway:WP43]]: Moved to stable identifier
14331view13:22, 22 May 2008SusanGrouping and connecting
11032view10:15, 4 March 2008EveloChanged name
11029view10:06, 4 March 2008Evelo[[Pathway:Homo sapiens:cytochrome 450]] moved to [[Pathway:Homo sapiens:cytochrome P450]]
11010view11:48, 3 March 2008ThomasModified categories
11009view11:47, 3 March 2008ThomasModified description
11008view11:44, 3 March 2008Thomasadded bibliography
11006view10:59, 3 March 2008Thomasadded more detailled reactions
11005view09:37, 3 March 2008Thomasadded CYP isoforms
10992view20:06, 2 March 2008MartijnVanIerseltranslated labels to english
10975view11:31, 28 February 2008Arikcytochrome P450 pathway

External references

View all...
NameTypeDatabase referenceComment
NADP+Metabolite18009 (ChEBI)
SubstrateEnzyme substrate (biology) (Wikipedia)
CYP20A1GeneProductENSG00000119004 (Ensembl)
CYP1A1GeneProductENSG00000140465 (Ensembl)
CYP7A1GeneProductENSG00000167910 (Ensembl)
CYP1A2GeneProductENSG00000140505 (Ensembl)
CYP27C1GeneProductENSG00000186684 (Ensembl)
CYP1B1GeneProductENSG00000138061 (Ensembl)
CYB5AGeneProductENSG00000166347 (Ensembl)
CYP2A6GeneProductENSG00000213052 (Ensembl)
CYP11B1GeneProductENSG00000160882 (Ensembl)
CYP2A7GeneProductENSG00000198077 (Ensembl)
CYP26B1GeneProductENSG00000003137 (Ensembl)
CYP2A13GeneProductENSG00000197838 (Ensembl)
activated O2Metabolite
CYP2B6GeneProductENSG00000197408 (Ensembl)
CYB5R3GeneProductENSG00000100243 (Ensembl)
CYP2C8GeneProductENSG00000138115 (Ensembl)
H2OMetaboliteHMDB02111 (HMDB)
CYP2C9GeneProductENSG00000138109 (Ensembl)
CYP8B1GeneProductENSG00000180432 (Ensembl)
CYP2C18GeneProductENSG00000108242 (Ensembl)
CYP17A1GeneProductENSG00000148795 (Ensembl)
CYP2D6GeneProductENSG00000100197 (Ensembl)
CYP24A1GeneProductENSG00000019186 (Ensembl)
CYP2E1GeneProductENSG00000130649 (Ensembl)
CYP27A1GeneProductENSG00000135929 (Ensembl)
CYP2F1GeneProductENSG00000197446 (Ensembl)
CYP46A1GeneProductENSG00000036530 (Ensembl)
CYP2G1PGeneProductENSG00000198461 (Ensembl)
PORGeneProductENSG00000127948 (Ensembl)
CYP2J2GeneProductENSG00000134716 (Ensembl)
CYB5R1GeneProductENSG00000159348 (Ensembl)
CYP2R1GeneProductENSG00000186104 (Ensembl)
NADHMetabolite16908 (ChEBI)
CYP2S1GeneProductENSG00000167600 (Ensembl)
Fe2+Metabolite29033 (ChEBI)
CYP2U1GeneProductENSG00000155016 (Ensembl)
CYP51A1GeneProductENSG00000001630 (Ensembl)
CYP2C19GeneProductENSG00000165841 (Ensembl)
CYP7B1GeneProductENSG00000172817 (Ensembl)
CYP3A4GeneProductENSG00000160868 (Ensembl)
CYP11A1GeneProductENSG00000140459 (Ensembl)
CYP2W1GeneProductENSG00000073067 (Ensembl)
CYP11B2GeneProductENSG00000179142 (Ensembl)
CYP4A11GeneProductENSG00000187048 (Ensembl)
CYP19A1GeneProductENSG00000137869 (Ensembl)
CYP3A43GeneProductENSG00000021461 (Ensembl)
CYP21A2GeneProductENSG00000198457 (Ensembl)
CYP3A7GeneProductENSG00000160870 (Ensembl)
CYP26A1GeneProductENSG00000095596 (Ensembl)
CYP3A5GeneProductENSG00000106258 (Ensembl)
CYP26C1GeneProductENSG00000187553 (Ensembl)
CYP4F3GeneProductENSG00000186529 (Ensembl)
CYP27B1GeneProductENSG00000111012 (Ensembl)
CYP4F2GeneProductENSG00000186115 (Ensembl)
CYP39A1GeneProductENSG00000146233 (Ensembl)
CYP4B1GeneProductENSG00000142973 (Ensembl)
CYPGeneProductCytochrome P450 (Wikipedia)
CYP4A22GeneProductENSG00000162365 (Ensembl)
Substrate-OHProduct (biology) (Wikipedia)
CYP4F22GeneProductENSG00000171954 (Ensembl)
NADPHMetabolite16474 (ChEBI)
CYP4F12GeneProductENSG00000186204 (Ensembl)
O2MetaboliteHMDB01377 (HMDB)
CYP4F11GeneProductENSG00000171903 (Ensembl)
CYB5R2GeneProductENSG00000166394 (Ensembl)
CYP4F8GeneProductENSG00000186526 (Ensembl)
CYB5R4GeneProductENSG00000065615 (Ensembl)
CYP4V2GeneProductENSG00000145476 (Ensembl)
NAD+Metabolite15846 (ChEBI)
CYP4X1GeneProductENSG00000186377 (Ensembl)
CYB5BGeneProductENSG00000103018 (Ensembl)
CYP4Z1GeneProductENSG00000186160 (Ensembl)
Fe3+Metabolite29034 (ChEBI)
Personal tools
Navigation