Synaptic Vesicle Pathway (Homo sapiens)

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Curation Tags

Description

Pathway depicting synaptic transmission of neurotransmitters from the presynaptic nerve terminal to the synaptic cleft upon depolarization. Synaptotagmin mediated transport along the nerve cell cytoskeleton indicates the initial step of this process. Originally created by Joanna S. Fong and Nathan Salomonis in the Bruce Conklin laboratory 5/12/2000 for use in GenMAPP. Genes associated with neurotransmitter reuptake from the synaptic left were obtained from the Gene Ontology term GO:0001504. For additional information see: http://en.wikipedia.org/wiki/Synaptic_vesicle

Ontology Tags

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
68907view17:30, 8 July 2013MaintBotUpdated to 2013 gpml schema
61690view22:19, 16 April 2013MaintBotremoved data source without identifer
59106view22:20, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
56444view21:42, 7 January 2013EgonwAdded a missing HMDB data source value.
53133view01:53, 30 October 2012MaintBotModified categories
50424view20:45, 15 August 2012NsalomonisSpecify description
50423view20:42, 15 August 2012NsalomonisSpecify description
50422view20:37, 15 August 2012NsalomonisModified description
50421view20:34, 15 August 2012NsalomonisSpecify description
50420view20:31, 15 August 2012NsalomonisSpecify description
50419view20:28, 15 August 2012NsalomonisPeriodical save, work in progress
50418view20:18, 15 August 2012NsalomonisPeriodical save, work in progress
50411view18:56, 15 August 2012NsalomonisSpecify description
50339view21:12, 12 August 2012NsalomonisOntology Term : 'synaptic vesicle cycle pathway' added !
50338view21:11, 12 August 2012NsalomonisModified description
50337view21:10, 12 August 2012NsalomonisModified description
50336view20:55, 12 August 2012NsalomonisSpecify description
50335view20:53, 12 August 2012NsalomonisPeriodical save, work in progress
50334view20:43, 12 August 2012NsalomonisPeriodical save, work in progress
50333view20:36, 12 August 2012NsalomonisSpecify description
50332view20:33, 12 August 2012NsalomonisPeriodical save, work in progress
50331view20:22, 12 August 2012NsalomonisPeriodical save, work in progress
50330view20:19, 12 August 2012NsalomonisSpecify description
50329view20:16, 12 August 2012NsalomonisSpecify description
50328view20:12, 12 August 2012NsalomonisPeriodical save, work in progress
50327view20:11, 12 August 2012NsalomonisSpecify description
50324view20:02, 12 August 2012NsalomonisPeriodical save, work in progress
50321view19:59, 12 August 2012NsalomonisSpecify description
50320view19:52, 12 August 2012NsalomonisPeriodical save, work in progress
50319view19:47, 12 August 2012NsalomonisSpecify description
50318view19:42, 12 August 2012NsalomonisPeriodical save, work in progress
50317view19:32, 12 August 2012NsalomonisPeriodical save, work in progress
50316view19:21, 12 August 2012NsalomonisSpecify description
50313view19:02, 12 August 2012NsalomonisPeriodical save, work in progress
50312view18:52, 12 August 2012NsalomonisPeriodical save, work in progress
50311view18:42, 12 August 2012NsalomonisPeriodical save, work in progress
50310view18:31, 12 August 2012NsalomonisNew pathway

External references

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NameTypeDatabase referenceComment
DNM3GeneProductENSG00000197959 (Ensembl)
RAB3AGeneProductENSG00000105649 (Ensembl)
SLC22A3GeneProductENSG00000146477 (Ensembl)
ATPMetabolite
AP2M1GeneProductENSG00000161203 (Ensembl)
DopamineMetaboliteHMDB00073 (HMDB)
GlutamateMetabolite
L-GlutamineMetaboliteHMDB00641 (HMDB)
AP2S1GeneProductENSG00000042753 (Ensembl)
SYN2GeneProductENSG00000157152 (Ensembl)
SLC17A6GeneProductENSG00000091664 (Ensembl)
SYN3GeneProductENSG00000185666 (Ensembl)
CLN8GeneProductENSG00000182372 (Ensembl)
SYT1GeneProductENSG00000067715 (Ensembl)
DNM1LGeneProductENSG00000087470 (Ensembl)
VAMP2GeneProductENSG00000220205 (Ensembl)
CLTCGeneProductENSG00000141367 (Ensembl)
STX1BGeneProductENSG00000099365 (Ensembl)
AP2A2GeneProductENSG00000183020 (Ensembl)
STX2GeneProductENSG00000111450 (Ensembl)
SLC17A8GeneProductENSG00000179520 (Ensembl)
STX1AGeneProductENSG00000106089 (Ensembl)
SLC18A2GeneProductENSG00000165646 (Ensembl)
STX3GeneProductENSG00000166900 (Ensembl)
PARK7GeneProductENSG00000116288 (Ensembl)
SNAP25GeneProductENSG00000132639 (Ensembl)
SLC6A4GeneProductENSG00000108576 (Ensembl)
RIMS1GeneProductENSG00000079841 (Ensembl)
SYN1GeneProductENSG00000008056 (Ensembl)
STXBP1GeneProductENSG00000136854 (Ensembl)
DNM2GeneProductENSG00000079805 (Ensembl)
UNC13CGeneProductENSG00000137766 (Ensembl)
CLTAGeneProductENSG00000122705 (Ensembl)
UNC13BGeneProductENSG00000198722 (Ensembl)
CLTCL1GeneProductENSG00000070371 (Ensembl)
UNC13AGeneProductENSG00000130477 (Ensembl)
AP2A1GeneProductENSG00000196961 (Ensembl)
CPLX3GeneProductENSG00000213578 (Ensembl)
AP2B1GeneProductENSG00000006125 (Ensembl)
CPLX2GeneProductENSG00000145920 (Ensembl)
SLC32A1GeneProductENSG00000101438 (Ensembl)
CPLX1GeneProductENSG00000168993 (Ensembl)
SLC17A7GeneProductENSG00000104888 (Ensembl)
NAPAGeneProductENSG00000105402 (Ensembl)
SLC18A1GeneProductENSG00000036565 (Ensembl)
NSFGeneProductENSG00000073969 (Ensembl)
SLC18A3GeneProductENSG00000187714 (Ensembl)
CACNA1AGeneProductENSG00000141837 (Ensembl)
SLC38A1GeneProductENSG00000111371 (Ensembl)
CACNA1BGeneProductENSG00000148408 (Ensembl)
SLC1A3GeneProductENSG00000079215 (Ensembl)
ADPMetabolite
SerotoninMetaboliteHMDB00259 (HMDB)
SYPGeneProductENSG00000102003 (Ensembl)
SLC25A4GeneProductENSG00000151729 (Ensembl)
DNM1GeneProductENSG00000106976 (Ensembl)
ATP1A2GeneProductENSG00000018625 (Ensembl)
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